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Article
Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas
The pharmacokinetics of high-dose fotemustine followed by autologous bone-marrow transplantation during a phase I–II clinical trial in 24 patients with glioblastoma or astrocytoma (grade III–IV) was investigat...
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Article
Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study
In the LMCE1 study using a single course of megatherapy most of the relapses occurred during the first 2 years after autologous bone marrow transplantation. A second pilot study (LMCE2) was therefore set up us...
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Chapter
Evaluation of Spruce Stand Transpiration By Sap Flow Measurements in the Vosges Mountains (Strengbach Catchment-France).
The Strengbach catchment is a multidisciplinary site for hydrological, geochemical and forest research in France. In order to record internal water transfers accurately, water balance measurements have been ca...
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Chapter
Influence of Various Stresses on Ca and Mg Nutrition of a Spruce Stand Developed on Acidic Soil.
In order to understand the relative influence of sylviculture and atmospheric deposition on spruce yellowing, an input/output budget has been developed in 3 adjacent stands of increasing ages. It appears that ...
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Article
Continuous vincristine infusion as part of a high dose chemoradiotherapy regimen: drug kinetics and toxicity
A 5-day continuous infusion of vincristine (VCR; total dose 4 mg/m2) has been given as part of a high-dose chemoradiotherapy regimen with bone marrow transplantation. Evidence of neurotoxicity, such as weakness, ...
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Article
Abdominal Burkitt-type lymphomas in Algeria
In a previous retrospective analysis from the principal paediatric centres of Algeria, Burkitt-type lymphomas (BL) were shown to account for around 46.5% of the total childhood non-Hodgkin's malignant lymphoma...
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Article
Properties of acebutolol in twenty patients with cardiac arrhythmias
Acebutolol (M & B 17,803 A), a new cardioselective beta-adrenergic blocking agent, was given intravenously to 20 selected patients with various cardiac arrhythmias. Cumulative doses ranging from 12.5 to 50 mg ...
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Article
Differential antianginal responsiveness to acebutolol
Six unselected males suffering from documented coronary insufficiency and grade II to III angina were submitted to graded multistage treadmill exercise test on 3 separate occasions, 3.5 hours after ingestion o...
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Article
Water intake: Influence on development of rat saline hypertension
Après 7 semaines de surcharge saline administrée par gavage, l'augmentation de tension artérielle systolique de 3 groupes de rats uninephrectomisés soumis à différents régimes d'hydratation s'avéra être en mei...
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Article
Pressor response to angiotensin I during cardio-pulmonary bypass
La réponse pressive systémique à des injections intra-artérielles d'angiotensine I et II a été étudiée chez deux chiens avant et après avoir totalement exclu les poumons de la circulation. La réactivité à l'an...
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Article
Effects of angiotensin on the superior cervical ganglion of the cat
En quantités inférieures à 10 picogrammes, l'angiotensine inhibe la transmission synaptique du ganglion cervical supérieur du chat, et cet effet est antagonise par la dihydroergotamine. En quantités supérieure...
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Article
Plasma Angiotensinase Activity in Human Hypertension
ANGIOTENSIN is the pressure-active component of the renal pressor system and is suspected of playing a part in cases of human hypertension accompanied by primary or secondary renal lesions. The angiotensin-lev...
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Article
Electrophoretic Behaviour of Serum Angiotensinase
WHEN angiotensin is introduced into the circulation, it quickly disappears as a result of degradation by serum angiotensinase, and uptake by the tissues and degradation by their respective angiotensinase activ...
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Chapter
Adrenocortical function in essential hypertension
For the last 12 years, our main research work has been devoted to the study of the possible relationship of adrenocortical hormones and arterial hypertension in humans. Much clinical and experimental evidence,...