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  1. No Access

    Article

    Phase I pharmacokinetics study of high-dose fotemustine and its metabolite 2-chloroethanol in patients with high-grade gliomas

    The pharmacokinetics of high-dose fotemustine followed by autologous bone-marrow transplantation during a phase I–II clinical trial in 24 patients with glioblastoma or astrocytoma (grade III–IV) was investigat...

    B. Tranchand, C. Lucas, P. Biron, B. Giroux in Cancer Chemotherapy and Pharmacology (1993)

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    Article

    Double megatherapy and autologous bone marrow transplantation for advanced neuroblastoma: the LMCE2 study

    In the LMCE1 study using a single course of megatherapy most of the relapses occurred during the first 2 years after autologous bone marrow transplantation. A second pilot study (LMCE2) was therefore set up us...

    T Philip, R Ladenstein, JM Zucker, R Pinkerton, E Bouffet in British Journal of Cancer (1993)

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    Chapter

    Evaluation of Spruce Stand Transpiration By Sap Flow Measurements in the Vosges Mountains (Strengbach Catchment-France).

    The Strengbach catchment is a multidisciplinary site for hydrological, geochemical and forest research in France. In order to record internal water transfers accurately, water balance measurements have been ca...

    P. Biron, A. Granier, P. Lu in Responses of Forest Ecosystems to Environmental Changes (1992)

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    Chapter

    Influence of Various Stresses on Ca and Mg Nutrition of a Spruce Stand Developed on Acidic Soil.

    In order to understand the relative influence of sylviculture and atmospheric deposition on spruce yellowing, an input/output budget has been developed in 3 adjacent stands of increasing ages. It appears that ...

    E. Dambrine, J. Ranger, B. Pollier in Responses of Forest Ecosystems to Environm… (1992)

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    Article

    Continuous vincristine infusion as part of a high dose chemoradiotherapy regimen: drug kinetics and toxicity

    A 5-day continuous infusion of vincristine (VCR; total dose 4 mg/m2) has been given as part of a high-dose chemoradiotherapy regimen with bone marrow transplantation. Evidence of neurotoxicity, such as weakness, ...

    C. R. Pinkerton, B. McDermott, T. Philip, P. Biron in Cancer Chemotherapy and Pharmacology (1988)

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    Article

    Abdominal Burkitt-type lymphomas in Algeria

    In a previous retrospective analysis from the principal paediatric centres of Algeria, Burkitt-type lymphomas (BL) were shown to account for around 46.5% of the total childhood non-Hodgkin's malignant lymphoma...

    Y Ladjadj, T Philip, G M Lenoir, F Z Tazerout, K Bendisari in British Journal of Cancer (1984)

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    Article

    Properties of acebutolol in twenty patients with cardiac arrhythmias

    Acebutolol (M & B 17,803 A), a new cardioselective beta-adrenergic blocking agent, was given intravenously to 20 selected patients with various cardiac arrhythmias. Cumulative doses ranging from 12.5 to 50 mg ...

    P. Biron, A. Proulx, L. Lapointe, R. Nadeau in European Journal of Clinical Pharmacology (1975)

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    Article

    Differential antianginal responsiveness to acebutolol

    Six unselected males suffering from documented coronary insufficiency and grade II to III angina were submitted to graded multistage treadmill exercise test on 3 separate occasions, 3.5 hours after ingestion o...

    P. Biron, G. Tremblay in European Journal of Clinical Pharmacology (1975)

  9. Article

    Water intake: Influence on development of rat saline hypertension

    Après 7 semaines de surcharge saline administrée par gavage, l'augmentation de tension artérielle systolique de 3 groupes de rats uninephrectomisés soumis à différents régimes d'hydratation s'avéra être en mei...

    Elizabeth Cousineau, P. Biron in Experientia (1972)

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    Article

    Pressor response to angiotensin I during cardio-pulmonary bypass

    La réponse pressive systémique à des injections intra-artérielles d'angiotensine I et II a été étudiée chez deux chiens avant et après avoir totalement exclu les poumons de la circulation. La réactivité à l'an...

    P. Stanley, P. Biron in Experientia (1969)

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    Article

    Effects of angiotensin on the superior cervical ganglion of the cat

    En quantités inférieures à 10 picogrammes, l'angiotensine inhibe la transmission synaptique du ganglion cervical supérieur du chat, et cet effet est antagonise par la dihydroergotamine. En quantités supérieure...

    J. -C. Panisset, P. Biron, A. Beaulnes in Experientia (1966)

  12. Article

    Plasma Angiotensinase Activity in Human Hypertension

    ANGIOTENSIN is the pressure-active component of the renal pressor system and is suspected of playing a part in cases of human hypertension accompanied by primary or secondary renal lesions. The angiotensin-lev...

    P. BIRON, R. LANDESMAN, J. C. HUNT in Nature (1964)

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    Article

    Electrophoretic Behaviour of Serum Angiotensinase

    WHEN angiotensin is introduced into the circulation, it quickly disappears as a result of degradation by serum angiotensinase, and uptake by the tissues and degradation by their respective angiotensinase activ...

    D. KLAUS, P. BIRON in Nature (1964)

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    Chapter

    Adrenocortical function in essential hypertension

    For the last 12 years, our main research work has been devoted to the study of the possible relationship of adrenocortical hormones and arterial hypertension in humans. Much clinical and experimental evidence,...

    J. Genest, W. Nowaczynski, E. Koiw, T. Sandor, P. Biron in Essential Hypertension (1960)

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