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  1. Article

    Open Access

    Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis–associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects

    Nonalcoholic steatohepatitis (NASH) is a hepatic phenotype of the metabolic syndrome, and increases the risk of cirrhosis and hepatocellular carcinoma (HCC). Although increasing evidence points to the therapeu...

    Mitsuhiro Kawakubo, Miyako Tanaka, Kozue Ochi, Akiko Watanabe in Scientific Reports (2020)

  2. Article

    Open Access

    Effect of weight change and lifestyle modifications on the development or remission of nonalcoholic fatty liver disease: sex-specific analysis

    The effects of changes in various lifestyle habits on nonalcoholic fatty liver disease (NAFLD) have not been well elucidated. We aimed to clarify how weight change and lifestyle modifications were associated w...

    Naoki Yoshioka, Masatoshi Ishigami, Yasuko Watanabe, Hajime Sumi in Scientific Reports (2020)

  3. No Access

    Article

    The impact of the excimer laser on myocardial salvage in ST-elevation acute myocardial infarction via nuclear scintigraphy

    Data on the efficacy of excimer laser coronary atherectomy (ELCA) for patients with ST-elevation myocardial infarction (STEMI) are limited. Therefore, we sought to evaluate the impact of ELCA on myocardial sal...

    Naoki Shibata, Kensuke Takagi in The International Journal of Cardiovascula… (2020)

  4. No Access

    Article

    Rapid identification of Gloriosa superba and Colchicum autumnale by melting curve analysis: application to a suicide case involving massive ingestion of G. superba

    The plant species Gloriosa superba and Colchicum autumnale produce extremely poisonous colchicine as a major toxic metabolite. Almost all previous studies on colchicine poisoning have focused on drug analysis and...

    Makoto Sakurada, Naoki Yoshioka, Azumi Kuse in International Journal of Legal Medicine (2019)

  5. Article

    Open Access

    Macroscopic fundamental diagram in simple street networks

    Macroscopic fundamental diagrams (MFDs) on simple street networks are studied analytically and numerically. We consider nonlinear circuit model that consists of road elements with piecewise linear fundamental ...

    Naoki Yoshioka, Kenji Terada, Takashi Shimada in Journal of Computational Social Science (2019)

  6. No Access

    Article

    Neointimal hyperplasia covering the intraluminal neo-metal carina 12 years after the simultaneous kissing stenting technique was performed: insight from optical frequency domain imaging findings

    Naoki Yoshioka, Kensuke Takagi in Cardiovascular Intervention and Therapeuti… (2018)

  7. No Access

    Article

    Macroscopic fundamental diagram in simple model of urban traffic

    Macroscopic fundamental diagram (MFD) is a reproducible unimodal relation between average vehicle density and average flow rate in urban traffic. Although this idea is tested by a few observations and simulati...

    Naoki Yoshioka, Takashi Shimada, Nobuyasu Ito in Artificial Life and Robotics (2017)

  8. Article

    Open Access

    Promoting notification and linkage of HBs antigen and anti-HCV antibody-positive patients through hospital alert system

    In Japan, approximately 0.9% and 1% of the whole population are infected with HBV and HCV, respectively. Doctors from departments other than gastroenterology often order viral hepatitis tests before an invasiv...

    Naoki Yoshioka, Akihiko Okumura, Yukie Yamamoto in BMC Infectious Diseases (2017)

  9. No Access

    Chapter

    Crystal Engineering Approach Toward Molecule-Based Magnetic Materials

    The crystal engineering approach toward molecule-based magnetic materials by controlling the molecular arrangement of the stable radical based on the directionality of the hydrogen bonding is described in conn...

    Naoki Yoshioka in Advances in Organic Crystal Chemistry (2015)

  10. No Access

    Article

    A simple method for the simultaneous determination of mushroom toxins by liquid chromatography–time-of-flight mass spectrometry

    A simple and rapid method for the determination of nine mushroom toxins, ibotenic acid, propargylglycine, choline, muscimol, muscarine, α-amanitin, β-amanitin, phalloidin, and phallacidin, in mushroom samples ...

    Naoki Yoshioka, Shigeki Akamatsu, Takao Mitsuhashi, Chikage Todo in Forensic Toxicology (2014)

  11. Article

    Open Access

    Experimental system for measurement of radiologists’ performance by visual search task

    Detective performance of radiologists for “obvious” targets should be evaluated by visual search task instead of ROC analysis, but visual task have not been applied to radiology studies. The aim of this study ...

    Eriko Maeda, Takeharu Yoshikawa, Ryoichi Nakashima, Kazufumi Kobayashi in SpringerPlus (2013)

  12. No Access

    Article

    Creep rupture due to thermally induced cracking

    We study sub-critical fracture driven by thermally activated crack nucleation in the framework of a fiber bundle model. Based on analytic calculations and computer simulations we show that in the presence of s...

    Naoki Yoshioka, Ferenc Kun, Nobuyasu Ito in MRS Online Proceedings Library (2013)

  13. No Access

    Article

    Rapid and sensitive quantification of paraquat and diquat in human serum by liquid chromatography/time-of-flight mass spectrometry using atmospheric pressure photoionization

    We developed a rapid and sensitive liquid chromatography/time-of-flight mass spectrometry (LC/TOF–MS) method using atmospheric pressure photoionization (APPI) for the determination of paraquat and diquat in hu...

    Naoki Yoshioka, Migiwa Asano, Azumi Kuse, Tomofumi Matsuoka in Forensic Toxicology (2012)

  14. No Access

    Article

    Comparison of CT findings of biliary tract changes with autoimmune pancreatitis and extrahepatic bile duct cholangiocarcinoma

    To retrospectively evaluate criteria for differentiating biliary tract changes in autoimmune pancreatitis (AIP-BTC) from extrahepatic cholangiocarcinoma (ECCA) based on CT findings and to determine predictors ...

    Eriko Maeda, Masaaki Akahane, Naoki Yoshioka in Japanese Journal of Radiology (2012)

  15. No Access

    Article

    Precision of the measurement of CT numbers: comparison of dual-energy CT spectral imaging with fast kVp switching and conventional CT with phantoms

    To compare dual-energy computed tomography (CT) spectral imaging and conventional CT imaging in terms of precision of the measurement of CT numbers in phantoms.

    Izuru Matsuda, Masaaki Akahane, Jiro Sato, Masaki Katsura in Japanese Journal of Radiology (2012)

  16. No Access

    Article

    Radiology reading-caused fatigue and measurement of eye strain with critical flicker fusion frequency

    The aim of this study was to investigate eye fatigue that could impair diagnostic accuracy by measuring the critical flicker fusion frequency (CFFF) before and after reading.

    Eriko Maeda, Takeharu Yoshikawa, Naoto Hayashi in Japanese Journal of Radiology (2011)

  17. No Access

    Article

    Adaptive statistical iterative reconstruction for volume-rendered computed tomography portovenography: improvement of image quality

    Adaptive statistical iterative reconstruction (ASIR) is a reconstruction technique for computed tomography (CT) that reduces image noise. The purpose of our study was to investigate whether ASIR improves the q...

    Izuru Matsuda, Shohei Hanaoka, Masaaki Akahane, Jiro Sato in Japanese Journal of Radiology (2010)

  18. No Access

    Article

    Do radial arterial pressure curves have diagnostic validity for identify severe aortic stenosis?

    A pulsus parvus et tardus of the carotid artery, i.e., a small weak pulse with a delayed systolic peak, is a well-recognized clinical finding of aortic stenosis (AS). However, the diagnostic value of radial ar...

    Naoki Yoshioka, Yoshihisa Fujita, Takeshi Yasukawa, Itsuro Sano in Journal of Anesthesia (2010)

  19. No Access

    Chapter and Conference Paper

    Preliminary Study on Appearance-Based Detection of Anatomical Point Landmarks in Body Trunk CT Images

    Anatomical point landmarks as most primitive anatomical knowledge are useful for medical image understanding. In this study, we propose a detection method for anatomical point landmark based on appearance mode...

    Mitsutaka Nemoto, Yukihiro Nomura, Shohei Hanaoka in Machine Learning in Medical Imaging (2010)

  20. No Access

    Article

    Bezier surface reformation: an original visualization technique of cervical nerve roots on myelographic CT

    The aim of this study was to assess the feasibility of an original reformation method of cervical myelographic computed tomography (CT) using the Bezier surface technique.

    Naoki Yoshioka, Naoto Hayashi, Masaaki Akahane, Takeharu Yoshikawa in Radiation Medicine (2006)

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