![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
245 Result(s)
-
Chapter and Conference Paper
Identification of Dynamic Characteristics of a Heritage Building - Yingxian Wooden Pagoda
The Yingxian Wooden Pagoda stands as China's oldest surviving wooden pagoda, boasting a substantial base diameter of 30.27 m and a towering height of 67.31 m. Over its extensive lifespan, both its local compon...
-
Chapter and Conference Paper
BCSNP-ML: A Novel Breast Cancer Prediction Model Base on LightGBM and Estrogen Metabolic Enzyme Genes
Estrogen-related metabolic enzyme gene polymorphisms have been demonstrated to be linked to breast cancer, and in this paper, a novel noninvasive breast cancer prediction model was developed utilizing machine ...
-
Article
Modeling and vibration feature analysis of a spur gear-bearing system with a misaligned shaft angle
A gear-bearing dynamic model is presented to investigate the vibration features of the system with a misaligned shaft angle. The time-varying mesh stiffness (TVMS), time-varying pressure angle and eccentricity...
-
Article
Open AccessPotential value of gastrointestinal myoelectrical activity in the diagnosis of anxiety-depression disorder: a population-based study
Depression and anxiety are frequently coexisted mental illness. The lack of solid objective diagnostic criteria has led to a high rate of suicide. The brain-gut axis bridges the gastrointestinal system with ne...
-
Article
Open AccessA cleavable chimeric peptide with targeting and killing domains enhances LPS neutralization and antibacterial properties against multi-drug resistant E. coli
Pathogenic Escherichia coli is one of the most common causes of diarrhea diseases and its characteristic component of the outer membrane-lipopolysaccharide (LPS) is a major inducer of sepsis. Few drugs have been ...
-
Article
Open AccessEfficient ilamycins production utilizing Enteromorpha prolifera by metabolically engineered Streptomyces atratus
With the invasion of green tides and the increase of urban green areas worldwide, multimillion tons of Enteromorpha need to be reutilized. In this study, Enteromorpha prolifera powder is considered a promising bi...
-
Article
Open AccessAdipose transplantation improves olfactory function and neurogenesis via PKCα-involved lipid metabolism in Seipin Knockout mice
Lipodystrophy-associated metabolic disorders caused by Seipin deficiency lead to not only severe lipodystrophy but also neurological disorders. However, the underlying mechanism of Seipin deficiency-induced ne...
-
Article
Open AccessToxoplasma gondii adhesion and apoptosis of chicken erythrocytes
Toxoplasma gondii is thought to infect all nucleated cells in warm-blooded animals, including poultry, mammals, and humans. However, it is unclear whether T. gondii can infect chicken erythrocytes due to the nucl...
-
Article
Quantitative study of aortic strain injuries originating from traffic accidents
Aortic injuries are the second leading cause of death after head injuries due to traffic accidents, and strain-induced injuries are becoming increasingly prominent. The quantitative study of aortic strain inju...
-
Article
Open AccessRutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase
Triple-negative breast cancer (TNBC) is one of the most aggressive human cancers and has poor prognosis. Approximately 80% of TNBC cases belong to the molecular basal-like subtype, which can be exploited thera...
-
Article
Open AccessShortening/re-lengthening and nailing versus bone transport for the treatment of segmental femoral bone defects
Segmental femoral bone defects are a severe challenge for orthopedic trauma surgeons. The objective of this study was to compare the efficacy of the shortening/re-lengthening and nailing (SRN) technique with t...
-
Article
Open AccessIncreased age, bilirubin, international normalized ratio, and creatinine score to triglyceride ratio are associated with alcohol-associated primary liver carcinoma: a single-centered retrospective study
This study analyzed the clinical features and biomarkers of alcohol-associated liver disease (ALD) to investigate the diagnostic value of age, bilirubin, international normalized ratio (INR), and creatinine (A...
-
Article
Sensitive and discriminative detection of cysteine by a Nile red-based NIR fluorescence probe
Cysteine (Cys) is a significant biological mercaptan that achieves key roles in several important physiological processes, such as reversible redox homeostasis in living organisms. Abnormal levels of Cys in th...
-
Article
Open AccessPharmacokinetics and Safety of iGlarLixi in Healthy Chinese Participants: Results of a Phase 1 Randomized Study
The Chinese Diabetes Society recommends basal insulin and glucagon-like peptide-1 receptor agonists as an add-on therapy to first-line oral antihyperglycemic drugs for people with type 2 diabetes (T2D). Fixed-...
-
Article
Static Magnetic Fields Promote Generation of Muscle Lineage Cells from Pluripotent Stem Cells and Myoblasts
Static magnetic fields (SMFs) exhibit numerous biological effects and regulate the proliferation and differentiation of several adult stem cells. However, the role of SMFs in the self-renewal maintenance and d...
-
Article
Lactoferrin, a Great Wall of host-defence?
-
Article
Effects of dietary supplementation of bovine lactoferrin on growth performance, immune function and intestinal health in weaning piglets
Weaning is a crucial period in the pig’s life cycle, which is frequently followed by gastrointestinal (GI) infections, diarrhea and even death. This study focused on the impact of bovine lactoferrin (bLF) supp...
-
Article
Open AccessLong non-coding RNA KCND1 protects hearts from hypertrophy by targeting YBX1
Cardiac hypertrophy is a common structural remodeling in many cardiovascular diseases. Recently, long non-coding RNAs (LncRNAs) were found to be involved in the physiological and pathological processes of card...
-
Article
Open AccessA Bioequivalence Study of Ezetimibe/Rosuvastatin Fixed Dose Combination (10 mg/10 mg) Versus the Individual Formulations Taken Concomitantly
This study evaluated the bioequivalence of ezetimibe/rosuvastatin fixed dose combination compared to the concomitant administration of individual formulations (ezetimibe and rosuvastatin) in Chinese healthy su...
-
Article
Open AccessIncreased TG to HDL-C ratio is associated with severity of drug-induced liver injury
We investigated the relationship between dyslipidemia and drug-induced liver injury (DILI), especially the level of triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) in severe DILI. In this...