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Article
Revealing diverse alternative splicing variants of the highly homologous SMN1 and SMN2 genes by targeted long-read sequencing
The survival of motor neuron (SMN) genes, SMN1 and SMN2, are two highly homologous genes related to spinal muscular atrophy (SMA). Different patterns of alternative splicing have been observed in the SMN genes. I...
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Article
Role of Hfq in glucose utilization, biofilm formation and quorum sensing system in Bacillus subtilis
Hfq is an RNA-binding protein, its main function is to participate in post-transcriptional regulation of bacteria and regulate small regulatory RNA (sRNA) and messenger RNA (mRNA) stability, but the Hfq functi...
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Article
Open AccesscircFAM120B functions as a tumor suppressor in esophageal squamous cell carcinoma via the miR-661/PPM1L axis and the PKR/p38 MAPK/EMT pathway
Extensive changes of circRNA expression underscore their essential contributions to multiple hallmarks of cancers; however, their functions and mechanisms of action in esophageal squamous cell carcinoma (ESCC)...
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Article
Polyurethane foam sampling for the determination of acetochlor in the air of workplace-gas chromatography
The studies of Acetochlor mainly focus on the detection of environmental residues and the assessment of behavioral patterns in the environment, but there is little information on the studies related to Acetoch...
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Article
Characterization of the microRNA transcriptomes and proteomics of cochlear tissue-derived small extracellular vesicles from mice of different ages after birth
The cochlea is an important sensory organ for both balance and sound perception, and the formation of the cochlea is a complex developmental process. The development of the mouse cochlea begins on embryonic da...
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Article
Transcriptome and DNA methylome analyses provide insight into the heterosis in flag leaf of inter-subspecific hybrid rice
Flag leaf heterosis of inter-subspecific hybrid rice is suggested to be related to leaf area, gene expression pattern and allele-specific expression, putatively related to DNA methylation differences between t...
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Article
Fabrication of carbon dots for sequential on–off-on determination of Fe3+ and S2− in solid-phase sensing and anti-counterfeit printing
Glutathione and 2-aminopyridine are used as carbon sources to prepare carbon dots (CDs) by a one-step hydrothermal reaction. The results show that the average particle diameter of CDs is 8.64 nm with uniform s...
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Article
Gastrointestinal Symptoms Onset in COVID-19 Patients in Wuhan, China
Early detection is critical in limiting the spread of 2019 novel coronavirus (COVID-19). Although previous data revealed characteristics of GI symptoms in COVID-19, for patients with only GI symptoms onset, th...
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Article
RNA-binding protein Hfq plays a vital role in cellulose decomposition throughout affecting cellulase gene expression
To study the function of the RNA-binding protein Hfq in Bacillus subtilis cellulose decomposition.
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Article
A kinetic study on the methanol conversion to dimethyl ether over H-ZSM-5 zeolite
The intrinsic kinetics of the methanol dehydration to dimethyl ether (DME) over commercial ZSM-5 zeolite is studied both theoretically and experimentally to establish the rate equation of the process. A set of...
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Article
Exogenous NO induces apoptosis of hepatocellular carcinoma cells via positive p38/JNK signaling pathway and negative ERK signaling pathways
JS-K as an exogenous NO donor could release NO after activation by glutathione S-transferases (GSTs). The present study explores the effects of JS-K on MAPK pathway in HepG2 and Bel-7402 cells. JS-K significan...
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Article
Lysobacter gilvus sp. nov., isolated from activated sludge
Strain HX-5-24T was isolated from the sludge collected from the outlet of the biochemical treatment facility of an agricultural chemical plant in Maanshan city, Anhui province, PR China (118° 28′ N, 31° 47′ E). C...
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Article
Broadband Microwave Absorber with a Double-Split Ring Structure
In this paper, we present a novel broadband microwave absorber. Each unit in the metamaterial consists of a layer of dielectric material sandwiched between two layers of metal patches. Due to metal-dielectric-...
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Article
3D graphene–carbon nanotubes-based solid-phase extraction technique combined with GC–MS for the determination of organophosphorus pesticides in water samples
Three-dimensional graphene–carbon nanotubes were prepared by the chemical reduction of a mixed aqueous solution of carboxylated multiwalled carbon nanotubes (C-MWCNTs) and graphene oxide, followed by freeze-dr...
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Article
Silanized carbon dot-based thermo-sensitive molecularly imprinted fluorescent sensor for bovine hemoglobin detection
Using the surface molecular imprinting technique, a thermo-sensitive molecularly imprinted fluorescent sensor was constructed for bovine hemoglobin (BHb) detection with the silanized carbon dots (CD@SiO2) as fluo...
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Article
Zinc Deficiency Promoted Fibrosis via ROS and TIMP/MMPs in the Myocardium of Mice
Zinc (Zn) is an important trace element in the body that has antioxidant effects. It has been proven that Zn deficiency can cause oxidative stress. The purpose of the present study was to clarify the effect an...
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Article
The bHLH gene family and its response to saline stress in Jilin ginseng, Panax ginseng C.A. Meyer
Basic helix–loop–helix (bHLH) gene family is a gene family of transcription factors that plays essential roles in plant growth and development, secondary metabolism and response to biotic and abiotic stresses. Th...
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Article
The Activation of Heat-Shock Protein After Copper(II) and/or Arsenic(III)-Induced Imbalance of Homeostasis, Inflammatory Response in Chicken Rectum
Arsenic and copper, two toxic pollutants, are powerful inducers of oxidative stress. Exposure to copper and arsenic can cause intestinal injury in cockerel. This study was carried out to investigate the effect...
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Article
Zinc Deficiency Promotes Testicular Cell Apoptosis in Mice
Zinc (Zn) plays an important role in spermatogenesis, and carbon tetrachloride (CCl4) induces testicular oxidative damage and cell death. The objective of the present study was to define the effects of Zn deficie...
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Article
Zinc Deficiency Induces Oxidative Damage and Causes Spleen Fibrosis
Zinc (Zn) is an essential trace element for animals. Zn controls the action of more than 300 enzymes and plays an important role in the regulation of gene expression. Evidence has shown that Zn has an antioxid...