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Article
A role for Ni in the hormonal stimulation of adenylate cyclase
The best understood system for transduction of extracellular messages into intracellular signals is the hormone receptor-coupled adenylate cyclase. In such systems receptors are functionally coupled to the enz...
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Article
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
The β-adrenergic receptor binding subunits from frog erythrocytes, hamster lung and guinea pig lung have been purified to apparent homogeneity and in all cases reside on a single polypeptide. Insertion of the ...
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Article
Temperature immutability of adenyl cyclase-coupled β adrenergic recptors
OBSERVATIONS from several laboratories have suggested that the well established classification of adrenergic receptors into α and β subtypes is not immutable. Several groups have reported that in isolated perfuse...