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Chapter
Application of the Factor Analysis to the Monitoring of the Changes in Protein Structure by Circular Dichroism
Circular dichroism (CD) spectroscopy is a useful tool for the detection of changes in both the secondary and tertiary structure of proteins induced by processes such as, protein folding. Despite the big amount...
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Chapter
A Chiral Co(II)-Thiolate Clusters Determination in Peptides by Circular Dichroism-Multicomponent Analysis
Metallothioneins (MT) are a class of proteins with a high content in cysteine, which provides them with an especial ability to bind metal ions which is the responsible of its physiological roles like the seque...
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Chapter and Conference Paper
In Vitro Modulation of Multidrug Resistance by BIBW22BS in Blasts of De Novo or Relapsed or Persistent AML
Drug resistance to chemotherapy is an important factor of treatment failure in acute myeloid leukemia (AML). One type of resistance, the multidrug resistance (MDR), can develop after exposure to certain natura...
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Article
Miscellaneous III
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Article
The complete DNA sequence of yeast chromosome III
The entire DNA sequence of chromosome III of the yeast Saccharomyces cerevisiae has been determined. This is the first complete sequence analysis of an entire chromosome from any organism. The 315-kilobase sequen...
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Article
Antiviral activity of a synthetic analog of prostaglandin A in mice infected with influenza A virus
We have previously shown that prostaglandins of the A series potently inhibit virus replication in several virus-host systems in vitro. In the present report we have studied the effect of a long-acting synthet...
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Article
Studies on the mechanism of entry of vaccinia virus in animal cells
In order to study the mechanism of entry of vaccinia virus into cells the fate of virion associated polypeptides was investigated during infection of african green monkey kidney (BSC-40) cells with 35 S-methio...
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Article
Interferon inhibits Viral Protein Synthesis in L Cells infected with Vaccinia Virus
Viral RNA can be detected in L cells pretreated with interferon and infected with vaccinia virus, but protein synthesis ceases as early as 20 min after infection. The effect of interferon must therefore be at ...