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  1. Article

    FTY720 inhibits tubulointerstitial inflammation in albumin overload-induced nephropathy of rats via the Sphk1 pathway

    FTY720, a new immunomodulatory drug with low cytotoxicity, is currently used to treat multiple sclerosis. In this study, we investigated the effects of FTY720 on inflammatory cell infiltration in albumin overl...

    Min Xu, Dan Liu, Li-hong Ding, Kun-ling Ma, Min Wu, Lin-li Lv… in Acta Pharmacologica Sinica (2014)

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  2. Article

    Enalapril inhibits tubulointerstitial inflammation and NLRP3 inflammasome expression in BSA-overload nephropathy of rats

    Proteinuria is not only a common marker of renal disease, but also involved in renal tubulointerstitial inflammation and fibrosis. The aim of this study was to investigate the mechanisms underlying the protect...

    Li-hong Ding, Dan Liu, Min Xu, Hong Liu, Min Wu, Ri-ning Tang… in Acta Pharmacologica Sinica (2014)

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  3. Article

    Open Access

    Activation of renin-angiotensin system is involved in dyslipidemia-mediated renal injuries in apolipoprotein E knockout mice and HK-2 cells

    Dyslipidemia and activation of renin-angiotensin system (RAS) contribute to the progression of chronic kidney disease (CKD). This study investigated possible synergistic effects of intrarenal RAS activation wi...

    Jie Ni, Kun-Ling Ma, Chang-**an Wang, **g Liu, Yang Zhang… in Lipids in Health and Disease (2013)

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