2,065 Result(s)
within
Jun-**a **ao
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessMidbrain glutamatergic circuit mechanism of resilience to socially transferred allodynia in male mice
The potential brain mechanism underlying resilience to socially transferred allodynia remains unknown. Here, we utilize a well-established socially transferred allodynia paradigm to segregate male mice into pa...
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Article
Open AccessRevealing brain cell-stratified causality through dissecting causal variants according to their cell-type-specific effects on gene expression
The human brain has been implicated in the pathogenesis of several complex diseases. Taking advantage of single-cell techniques, genome-wide association studies (GWAS) have taken it a step further and revealed...
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Article
Pro-CRISPR PcrIIC1-associated Cas9 system for enhanced bacterial immunity
The CRISPR system is an adaptive immune system found in prokaryotes that defends host cells against the invasion of foreign DNA1. As part of the ongoing struggle between phages and the bacterial immune system, th...
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Article
Open AccessPhotocatalytic do** of organic semiconductors
Chemical do** is an important approach to manipulating charge-carrier concentration and transport in organic semiconductors (OSCs)1–3 and ultimately enhances device performance4–7. However, conventional do** ...
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Open AccessA dual spin-controlled chiral two-/three-dimensional perovskite artificial leaf for efficient overall photoelectrochemical water splitting
The oxygen evolution reaction, which involves high overpotential and slow charge-transport kinetics, plays a critical role in determining the efficiency of solar-driven water splitting. The chiral-induced spin...
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Open AccessCryo-EM structures of Thogoto virus polymerase reveal unique RNA transcription and replication mechanisms among orthomyxoviruses
Influenza viruses and thogotoviruses account for most recognized orthomyxoviruses. Thogotoviruses, exemplified by Thogoto virus (THOV), are capable of infecting humans using ticks as vectors. THOV transcribes ...
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Open AccessRobotic wireless capsule endoscopy: recent advances and upcoming technologies
Wireless capsule endoscopy (WCE) offers a non-invasive evaluation of the digestive system, eliminating the need for sedation and the risks associated with conventional endoscopic procedures. Its significance l...
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Article
Open AccessEthnic diversity and divergent perceptions of climate change: a case study in Southwest China
Understanding divergent perceptions of ethnic groups to climate change in mountainous regions home to multi-ethnic cultures and the factors influencing these perceptions is crucial for policymakers to predict ...
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Article
Open AccessMicrowave-transparent metallic metamaterials for autonomous driving safety
Maintaining the surface transparency of protective covers using transparent heaters in extreme weather is imperative for enhancing safety in autonomous driving. However, achieving both high transmittance and l...
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Open AccessVariability of relationship between inner-retinal structural changes and visual dysfunction in optic neuropathy
Optical coherence tomography (OCT) displays the retinal nerve fiber layer (RNFL) or macular ganglion cell and inner plexiform layer (GCIPL) thickness below 1st percentile in red color. This finding generally i...
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Article
Open AccessRemarkable flexibility in freestanding single-crystalline antiferroelectric PbZrO3 membranes
The ultrahigh flexibility and elasticity achieved in freestanding single-crystalline ferroelectric oxide membranes have attracted much attention recently. However, for antiferroelectric oxides, the flexibility...
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Open AccessAutomatic segmentation and classification of frontal sinuses for sex determination from CBCT scans using a two-stage anatomy-guided attention network
Sex determination is essential for identifying unidentified individuals, particularly in forensic contexts. Traditional methods for sex determination involve manual measurements of skeletal features on CBCT sc...
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Article
Open Access“Ion-imprinting” strategy towards metal sulfide scavenger enables the highly selective capture of radiocesium
Highly selective capture of radiocesium is an urgent need for environmental radioactive contamination remediation and spent fuel disposal. Herein, a strategy is proposed for construction of “inorganic ion-impr...
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Article
Open AccessTranscriptomic signature, bioactivity and safety of a non-hepatotoxic analgesic generating AM404 in the midbrain PAG region
Safe and effective pain management is a critical healthcare and societal need. The potential for acute liver injury from paracetamol (ApAP) overdose; nephrotoxicity and gastrointestinal damage from chronic non...
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Article
Open AccessAnti-inflammatory properties and characterization of water extracts obtained from Callicarpa kwangtungensis Chun using in vitro and in vivo rat models
Callicarpa kwangtungensis Chun (CK) is a common remedy exhibits anti-inflammatory properties and has been used in Chinese herbal formulations, such as KangGongYan tablets. It is the main component of KangGongYan ...
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Article
Open AccessInducible deletion of microRNA activity in kidney mesenchymal cells exacerbates renal fibrosis
MicroRNAs (miRNAs) are sequence-specific inhibitors of post-transcriptional gene expression. However, the physiological functions of these non-coding RNAs in renal interstitial mesenchymal cells remain unclear...
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Article
Open AccessAssociation between household size and risk of incident dementia in the UK Biobank study
Currently, the relationship between household size and incident dementia, along with the underlying neurobiological mechanisms, remains unclear. This prospective cohort study was based on UK Biobank participan...
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Open AccessDifferent association of atherogenic index of plasma with the risk of high platelet reactivity according to the presentation of acute myocardial infarction
This study evaluated the association of atherogenic index of plasma (AIP) with platelet reactivity and clinical outcomes according to acute myocardial infarction (AMI). The composite of 3-year adverse outcomes...
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Article
Open AccessAstroglial connexin 43 is a novel therapeutic target for chronic multiple sclerosis model
In chronic stages of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalitis (EAE), connexin (Cx)43 gap junction channel proteins are overexpressed because of astrogliosis. To elucid...
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Open AccessEffects of cooking with solid fuel on hearing loss in Chinese adults—Based on two cohort studies
The association between cooking fuel and hearing loss still needs more research to clarify, and two longitudinal cohort studies were explored to find if solid fuel use for cooking affected hearing in Chinese a...
