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Article
GPRC5A overexpression predicted advanced biological behaviors and poor prognosis in patients with gastric cancer
G protein-coupled receptor, family C, group 5, member A (GPRC5A) had received attentions for its role in carcinogenesis and prognostic values in several types of cancer. However, the functional roles of GPRC5A...
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Article
Metformin use improves the survival of diabetic combined small-cell lung cancer patients
Metformin has been reported having potential anticancer effect on kinds of solid tumors, but its role in combined small-cell lung cancer (C-SCLC) remains indistinct. This study aimed to explore whether metform...
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Article
Age-related alteration in cerebral blood flow and energy failure is correlated with cognitive impairment in the senescence-accelerated prone mouse strain 8 (SAMP8)
Cerebrovascular dysfunction is an early pathogenic event in Alzheimer’s disease (AD) and plays a key role in the disease process. Cerebral hypoperfusion, brain glucose hypometabolism and disrupted blood–brain ...
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Article
Hippocampal neuron loss is correlated with cognitive deficits in SAMP8 mice
The objective of this study is to examine whether neuron loss occurs in SAMP8 and whether neuron loss is correlated with cognitive deficits of these mice. Neuronal loss is considered as one of the most importa...
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Article
Effects of Acupuncture on Glycometabolic Enzymes in Multi-infarct Dementia Rats
Acupuncture has exhibited therapeutic effects on vascular dementia in our previous research. The mechanism of its anti-dementia effects involves energy metabolism. For brain cells, glucose metabolism is almost...
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Article
Biochemical analysis of argyrophilic nonhistone proteins in chromosomes of plantTriticum aestivum