314 Result(s)
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Article
Early-onset and late-onset Parkinson’s disease exhibit a different profile of gait and posture features based on the Kinect
Gait and posture abnormalities are the common disabling motor symptoms in Parkinson's disease (PD). This study aims to investigate the differential characteristics of gait and posture in early-onset PD (EOPD) ...
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Open AccessAssociation between serum PCSK9 and coronary heart disease in patients with type 2 diabetes mellitus
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is considered a new biomarker for atherosclerosis, but its ability to predict cardiovascular outcomes has been controversial. This study aimed to address t...
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Clinical analysis of 2790 children with retinoblastoma: a single-center experience in China
In this study, we aimed to analyze the clinical characteristics and prognosis of children with retinoblastoma (RB) in a single center in China with a large sample collection spanning 17 years.
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Open AccessDiagnostic Value of MRI Features in Dual-phenotype Hepatocellular Carcinoma: A Preliminary Study
This study aimed to explore the magnetic resonance imaging (MRI) features of dual-phenotype hepatocellular carcinoma (DPHCC) and their diagnostic value.The data of 208 patients with primary liver cancer were r...
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Open AccessShort- and long-term outcomes of patients with minor stroke and nonvalvular atrial fibrillation
Nonvalvular atrial fibrillation (NVAF) is a risk factor for stroke. This study was undertaken to determine the influence of NVAF on the mortality and recurrent stroke after a minor stroke event.
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Open AccessPopulation impact of fine particulate matter on tuberculosis risk in China: a causal inference
Previous studies have suggested the potential association between air pollution and tuberculosis incidence, but this association remains inconclusive and evidence to assess causality is particularly lacking. W...
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Correction to: Impact of boost sequence in concurrent chemo-radiotherapy on newly diagnosed IDH-wildtype glioblastoma multiforme
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Impact of boost sequence in concurrent chemo-radiotherapy on newly diagnosed IDH-wildtype glioblastoma multiforme
The standard of care for glioblastoma multiforme (GBM) is maximal surgical resection followed by conventional fractionated concurrent chemoradiotherapy (CCRT) with a total dose of 60 Gy. However, there is curr...
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Open AccessDALK combined intralamellar tectonic patch graft: an alternative approach to treat frank corneal perforation
Deep anterior lamellar keratoplasty (DALK) has gained popularity in cases of corneal thinning and leaking descemetocele. In this study, we introduced an intralamellar tectonic patch graft in addition to conven...
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Open AccessEfficacy of mouthwash on reducing salivary SARS-CoV-2 viral load and clinical symptoms: a systematic review and meta-analysis
COVID-19 has been a public health emergency of international concern (PHEIC) for a lengthy period of time. The novel coronavirus is primarily spread via aerosols at a short distance, with infected individuals ...
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Open AccessDevelopment of a novel mesh model to define a new index “amount of stone” to evaluate calculus and predicting the lithotripsy time
Develop a mesh model to define a new “index amount of stone” to evaluate calculus and predict lithotripsy time.
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Open AccessIdentification of FAT4 as a positive prognostic biomarker in DLBCL by comprehensive genomic analysis
The molecular landscapes of diffuse large B-cell lymphoma (DLBCL) remained to be comprehensively investigated with an urgent need to identify novel prognostic biomarkers guiding prognostic stratification and d...
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Dynamic contrast-enhanced MRI radiomics model predicts epidermal growth factor receptor amplification in glioblastoma, IDH-wildtype
To develop and validate a dynamic contrast-enhanced (DCE) MRI-based radiomics model to predict epidermal growth factor receptor (EGFR) amplification in patients with glioblastoma, isocitrate dehydrogenase (IDH) w...
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Open AccessOutcomes of pregnancy in women with different types of pulmonary hypertension
Pulmonary hypertension (PH) is considered to increase maternal and fetal risk, and we attempt to explore pregnancy outcomes in women with different types of PH.
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Open AccessAssessment of rehabilitation following subarachnoid haemorrhage in China: findings from the Chinese Stroke Center Alliance
Rehabilitation improves functional recovery in subarachnoid hemorrhage (SAH) patients, and assessing patients for rehabilitation is the first step in this process. However, little is known about clinical pract...
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Self-assembled nanoparticles based on DNA origami and a nitrated T helper cell epitope as a platform for the development of personalized cancer vaccines
Neoantigen vaccines constitute an emerging and promising cancer immunotherapy. However, not all neoantigens have anti-tumor activity, as poor CD4+ epitope recognition can lead to the lack of greatly limit the per...
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Open AccessDifferential expression of diacylglycerol kinase ζ is involved in inferior parietal lobule-related dysfunction in schizophrenia with cognitive impairments
Cognitive impairment is the main factor in the poor prognosis of schizophrenia, but its mechanism remains unclear. The inferior parietal lobule (IPL) is related to various clinical symptoms and cognitive impai...
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Open AccessTranscriptional level of inflammation markers associates with short-term brain structural changes in first-episode schizophrenia
Inflammation has been implicated in the pathology of schizophrenia and may cause neuronal cell death and dendrite loss. Neuroimaging studies have highlighted longitudinal brain structural changes in patients w...
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Open AccessVisit-to-visit HbA1c variability is associated with aortic stiffness progression in participants with type 2 diabetes
Glycemic variability plays an important role in the development of cardiovascular disease (CVD). This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic sti...
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Open AccessFrequency of prothrombin time-international normalized ratio monitoring and the long-term prognosis in patients with mechanical valve replacement
The study aimed to assess the correlation between the monitoring frequency of PT-INR and the long-term prognosis in patients with mechanical heart valve (MHV) replacement after discharge.
