46 Result(s)

Article

Establishment and characterization of a cisplatin-resistant cell line (IGSK-1) from a poorly differentiated gastric adenocarcinoma

We successfully established a spontaneously cisplatin-resistant tumor cell line (designated as IGSK-1) derived from original gastric carcinoma. The patient was a 75-year-old Japanese woman. The histopathologic...

Satoshi Ohi, Naoto Takahashi, Kouzou Ninomiya, Masako Nakajima… in Human Cell (2007)

Article

Establishment and characterization of a cell line (NABCA) derived from metastatic lymph nodes of breast scirrhous carcinoma

We successfully established a breast scirrhous carcinoma cell line (designated as NABCA) derived from metastatic tumors of the lymph node. The cells grew as multi-layered cultures without contact inhibition. T...

Satoshi Ohi, Shigeya Kyoda, Isao Tabei, Kouzou Ninomiya, Kayoko Sugiyama… in Human Cell (2006)

Article

Sizzled controls dorso-ventral polarity by repressing cleavage of the Chordin protein

The Bone morphogenetic protein (Bmp) signalling gradient has a major function in the formation of the dorso-ventral axis. The zebrafish ventralized mutant, ogon, encodes Secreted Frizzled (Sizzled). sizzled is ve...

Osamu Muraoka, Takashi Shimizu, Taijiro Yabe, Hideaki Nojima… in Nature Cell Biology (2006)

Article

cDNA cloning of Japanese oyster stress protein homologous to the mammalian 78-kDa glucose regulated protein and its induction by heatshock

The 78-kDa glucose regulated protein (GRP78), a member of stress proteins, was cloned from a cDNA library of Japanese oyster Crassostrea gigas. The analysis on Japanese oyster GRP78 clone of approximately 2.6 kb ...

Yoshihiro Yokoyama, Hisashi Hashimoto, Satoshi Kubota, Akira Kuriyama… in Fisheries Science (2006)

Article

Proliferation and tube formation of periodontal endothelial cells

Angiogenesis is indispensable to guide a regeneration of good periodontal tissue in the wound healing after periodontal surgery. Hepatocyte growth factor is well known for a strong angiogenic factor and it may...

Etsuko Sato, Hisashi Hashimoto, Hisahiro Kamoi, Toshiaki Tachibana… in Human Cell (2005)

Article

Abstract of Poster Presentation

Hiroshi Uchida, Tetsuo Maruyama, Jkuko Sugiura, Takashi Kajitani, Touru Arase… in Human Cell (2005)

Article

Establishment and characterization of a human malignant choroids plexus papilloma cell line (HIBCPP)

A cell line designated “HIBSPP” was established from a human malignant choroids plexus papilloma of 29-year-old Japanese woman. This line grew well without interruption for 3 years and was subcultivated over 7...

Isamu Ishiwata, Chieko Ishiwata, Emiko Ishiwata, Yoshiro Sato… in Human Cell (2005)

Article

Expression of HSP70 in response to heat-shock and its cDNA cloning from Mediterranean blue mussel

Expression of HSP70 in response to heat-shock was investigated at the protein and mRNA levels in Mediterranean blue mussel. Western and Northern blot analyses revealed that HSP70 was expressed following heat-s...

Haruhiko Toyohara, Masatomi Hosoi, Isao Hayashi, Satoshi Kubota… in Fisheries Science (2005)

Article

Establishment and characterization of EB virus-free normal B-lymphocyte and interleukin-6-producing poorly differentiated adenocarcinoma cell lines derived from gastric tumor tissue

We successfully established two cell lines, an adenocarcinoma cell line (designated as HIGS) and Epstein-Barr virus-free normal B-lymphocyte cell line (designated as HIGS-BL), derived from a moderately to poor...

Satoshi Ohi, Hisashi Hashimoto, Toshiaki Tachibana, Isao Tabei… in Human Cell (2005)

Article

Establishment and characterization of a human ovarian small cell carcinoma, hypercalcemic type, cell line (OS-1) secreting PTH, PTHrP and ACTH-special reference to the susceptibility of anti-cancer drugs-

We successfully established a novel cell line (OS-1) derived from human ovarian small cell carcinoma, hypercalcemic type secreted PTH, PTH-rP and ACTH. The OS-1 cell line was established from metastatic focus ...

Satoshi Ohi, Shigeki Niimi, Naoya Okada, Kyosuke Yamada, Toshiaki Tachibana… in Human Cell (2004)

Article

Abstracts of Poster Presentations

Megumi Iguchi, Isamu Ishiwata, Tomoharu Tamagawa, Chieko Ishiwata… in Human Cell (2004)

Article

Establishment and characterization of a nerve cell line (NC-HIMT) from HIMT cells derived from a human ovarian immature teratoma with special reference to the induction of neuron differentiation by retinoic acid

A nerve cell line designated NC-HIMT was established from a HIMT cell line derived from a benign ovarian, three germ layer immature teratoma removed from a 21-year-old Japanese female. The HIMT cells were elon...

Takashi Yokose, Hisashi Hashimoto, Toshiaki Tachibana, Satoshi Ohi… in Human Cell (2004)

Article

Establishment and characterization of a human gestational choriocarcinoma cell line (HOCC)

Human gestational choriocarcinoma cell line (HOCC) was established from the mouse graft of choriocarcinorna. The HOCC cells were spindle or polygonal in shape and multi-nucleated giant cells, showing neoplasti...

Isamu Ishiwata, Chieko Ishiwata, Akira Tsuiki, Kazushige Kiguchi… in Human Cell (2004)

Article

New method for forming large embryoid bodies using the wall of the culture dish along with an analysis of their structural characteristics

Early embryonic stem (EES) cells, which were established from 2 cell stage embryos obtained from ddY mice, had similar characteristics as embryonic stem (ES) cells. These cells were maintained in an undifferen...

Motoyoshi Yamamoto, Hisashi Hashimoto, Toshiaki Tachibana, Satoshi Ohi… in Human Cell (2004)

Article

The differentiation of early embryonic stem cells into adipocytes-like cells

An early embryonic stem cell line, EES-6 cells, was established fiom 2-cell stage embryos of ddY mice. The cells were maintained in an undifferentiated state with D-MEM/FlZ medium supplemented with 10% fetal b...

Motoyoshi Yamamoto, Toshiaki Tachibana, Hisashi Hashimoto, Isamu Ishiwata… in Human Cell (2003)

Article

New approach for the establishment of an hepatocyte cell line derived from rat early embryonic stem cells

A cell line with the characteristics of hepatocytes was established from rat early embryonic stem cells (REES). This cell line was established using a new novel method of Ishiwata et al. from two cell embryos ...

Isao Tabei, Hisashi Hashimoto, Isamu Ishiwata, Yuko Tokieda… in Human Cell (2003)

Article

Zinc finger protein too few controls the development of monoaminergic neurons

The mechanism controlling the development of dopaminergic (DA) and serotonergic (5HT) neurons in vertebrates is not well understood. Here we characterized a zebrafish mutant—too few (tof)—that develops hindbrain ...

Gil Levkowitz, Jörg Zeller, Howard I. Sirotkin, Dorothy French… in Nature Neuroscience (2003)

Article

Establishment and characterization of two squamous cell carcinoma cell lines (HYVC and HMVC) derived from vulva

Two cell lines, HYVC and HMVC, were established from cultures of the squamous cell carcinoma removed from the vulva of females of 37 and 46 years old, respectively. These cell lines were very similar in their ...

Kazushige Kiguchi, Isamu Ishiwata, Chieko Ishiwata, Masanori Iwata… in Human Cell (2002)

Article

Establishment and characterization of a lymphoepithelial-like carcinoma cell line (HUUCLEC) derived from the human uterine cervix

A cell line designated HUUCLEC was established from a human uterine cervical lymphoepithelial carcinoma obtained from a 61-year-old Japanese woman. The cell line has grown slowly without interruption and seria...

Kazushige Kiguchi, Isamu Ishwata, Yuko Tokieda, Megumi Iguchi… in Human Cell (2002)