1,342 Result(s)
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Guo-**n Jiang
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Article
Intermediate phase-assisted growth of CsPbBr3 for high performance of carbon-based perovskite solar cells
CsPbBr3 inorganic perovskites have been regarded as the promising materials in the field of photovoltaics because of the high tolerance against environment. The high energy barrier of phase transition from lead b...
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Article
Properties and microstructure of copper–titanium alloys with magnesium additions
The volume fractions and morphology of precipitates in precipitation-strengthened Cu-Ti alloys, which precipitate mainly as continuous and discontinuous precipitates, are important for the application of the a...
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Article
Open AccessDynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance
Although DHFR gene amplification has long been known as a major mechanism for methotrexate (MTX) resistance in cancer, the early changes and detailed development of the resistance are not yet fully understood.
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A New Perspective on the Semi-quantitative Meso-structural Failure Mechanism of Deep Weak Interlayer Zone Under Different Stress Paths
To essentially explore and quantitatively clarify the mesoscopic failure mechanism of deep weak interlayer zone (WIZ) induced by complex stress levels and stress paths (i.e., particle breakage and orientation,...
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Article
Ruthenium–dihydroartemisinin complex: a promising new compound for colon cancer prevention via G1 cell cycle arrest, apoptotic induction, and adaptive immune regulation
Artemisinin (ART) and its derivatives are important antimalaria agents and have received increased attention due to their broad biomedical effects, such as anticancer and anti-inflammation activities. Recently...
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Enhancing lithium-metal battery longevity through minimized coordinating diluent
Extending the lifespan of lithium (Li) batteries involves managing reactions at the Li anode and stabilizing the solid–electrolyte interphase (SEI) through strategic regulation of the electrolyte composition. ...
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Open Access50% efficacy dose of intravenous lidocaine in supressing sufentanil-induced cough in children: a randomised controlled trial
Opioids such as sufentanil are used as anaesthetics due to their rapid action and superior analgesic effect. However, sufentanil induces a huge cough in paediatric patients. In contrast, intravenous (IV) lidoc...
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Mechanical Modeling and Analysis of Stability Deterioration of Production Well During Marine Hydrate Depressurization Production
Different from oil and gas production, hydrate reservoirs are shallow and unconsolidated, whose mechanical properties deteriorate with hydrate decomposition. Therefore, the formations will undergo significant ...
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Article
Mechanisms of norcantharidin against renal tubulointerstitial fibrosis
Renal tubulointerstitial fibrosis (RTIF) is a common feature and inevitable consequence of all progressive chronic kidney diseases, leading to end-stage renal failure regardless of the initial cause. Although ...
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Article
Open AccessThe molecular characteristics could supplement the staging system of pT2/T3N0M0 esophageal squamous cell carcinoma: a translational study based on a cohort with over 20 years of follow-up
This study aimed to construct a model based on 23 enrolled molecules to evaluate prognoses of pT2/3N0M0 esophageal squamous cell carcinoma (ESCC) patients with up to 20 years of follow-up.
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Open AccessEffect of endoscopic therapy and drug therapy on prognosis and rebleeding in patients with esophagogastric variceal bleeding
Esophagogastric variceal bleeding (EVB) is one of the common digestive system emergencies with poor prognosis and high rate of rebleeding after treatment. To explore the effects of endoscopic therapy and drug ...
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Article
Open AccessExtracellular matrix protein 1 (ECM1) is a potential biomarker in B cell acute lymphoblastic leukemia
B cell acute lymphoblastic leukemia (ALL) is characterized by the highly heterogeneity of pathogenic genetic background, and there are still approximately 30–40% of patients without clear molecular markers. To...
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Open AccessBlood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer’s disease diagnosis and differential diagnosis
Accurate differential diagnosis among various dementias is crucial for effective treatment of Alzheimer’s disease (AD). The study began with searching for novel blood-based neuronal extracellular vesicles (EVs...
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Open AccessTBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro
There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet the urgent need for treatment.
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Article
Interfacial reaction between AZ91D magnesium alloy melt and mild steel under high temperature
The metallurgical quality control of magnesium (Mg) and Mg alloys in melting process is required to ensure a satisfied mechanical and corrosion performance, while the typical used steel crucible introduces imp...
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Article
Open AccessProteomic profiling of cerebrospinal fluid in pediatric myelin oligodendrocyte glycoprotein antibody-associated disease
Myelin oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder of the central nervous system.
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Article
Rail repair technology based on high-pressure abrasive water jet
To investigate the rail repair process based on high-pressure abrasive water jet, simulation analysis of its machining process is carried out based on smoothed particle hydrodynamics with finite element method...
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Article
SHP-1 inhibition targets leukaemia stem cells to restore immunosurveillance and enhance chemosensitivity by metabolic reprogramming
Leukaemia stem cells (LSCs) in acute myeloid leukaemia present a considerable treatment challenge due to their resistance to chemotherapy and immunosurveillance. The connection between these properties in LSCs...
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Bibliometric study and review of Klotho research: global characteristics and trends from 2000 to 2023
Although Klotho-related research has seen a significant upsurge, the field lacks comprehensive analytical representation and in-depth exploration of pertinent areas such as prevailing research trends and key f...
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Exploratory study on the metabolic similarity of denitrifying carbon sources
Mixed carbon sources have been developed for denitrification to eliminate the “carbon dependency” problem of single carbon. The metabolic correlation between different carbon sources is significant as guidance...
