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Article
Assessment of quadriceps muscle mass with ultrasound in critically ill patients: intra- and inter-observer agreement and sensitivity
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Article
Critical illness-induced dysglycemia and the brain
Dysglycemia is a characteristic feature of critical illness associated with adverse outcome. Whether dysglycemia contributes to brain dysfunction during critical illness and long-term neurological complication...
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Article
Understanding the HPA response to critical illness: novel insights with clinical implications
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Article
What’s new in glucose control in the ICU?
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Article
Does the surface-treated AN69 membrane prolong filter survival in CRRT without anticoagulation?
The need for continuous anticoagulation remains a significant drawback in continuous renal replacement therapy (CRRT), especially in patients with increased bleeding risk. Polyethyleneimine treatment of the AN...
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Article
Impact of a computer-generated alert system on the quality of tight glycemic control
To assess the impact of a computer-generated blood glucose (BG) alert, generated by a Patient Data Management System (PDMS) and superimposed on a paper-based guideline, on tight glycemic control (TGC) in the i...
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Chapter
Glucose, Insulin, and the Kidney
Several types of critical illness are associated with hyperglycemia and insulin resistance. This “diabetes of stress” used to be considered an adaptive response, beneficial for survival. This dogma was challen...
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Article
Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care
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Article
Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care
To investigate the effectiveness of an enhanced software Model Predictive Control (eMPC) algorithm for intravenous insulin infusion, targeted at tight glucose control in critically ill patients, over 72 h, in ...
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Article
Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?
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Article
Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?
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Article
Modulation of regional nitric oxide metabolism: Blood glucose control or insulin?
Tight glycaemic control by intensive insulin therapy (IIT) reduces morbidity and mortality in critically ill patients. As potential mechanisms contributing to the clinical benefits we hypothesized that glycaem...