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Article
Open AccessEndoscopic resection and allografting for benign osteolytic lesions of the calcaneus
Both unicameral bone cysts and intra-osseous lipoma of the calcaneus are rare entities which are mostly diagnosed due to unspecific heel pain, pathologic fracture or as an incidental finding. Minimally-invasiv...
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Article
Open AccessLong-term functional outcome and quality of life following rotationplasty for treatment of malignant tumors
Malignant bone tumors of the lower extremity are more frequently found in children and adolescents than in adults. Modern treatment regimens led to high limb salvage rates and offer the choice between endopros...
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Article
Open AccessManagement of musculoskeletal tumors during pregnancy: a retrospective study
In recent years, scientific research has increasingly focused on malignancies during pregnancy. However, the development of musculoskeletal tumors during pregnancy has only been the subject of a few studies so...
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Article
Open AccessDo human tumor-associated viruses play a role in the development of synovial sarcoma?
To date, the pathomechanism of soft tissue sarcomas such as synovial sarcoma remains unclear whereas even a viral etiology was suspected. Aim of this study was to analyze whether EBV, HHV-8 or HPV play a role ...
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Pathological Fracture of the Humerus
In general usually pathological fractures are caused by an inadequate trauma to the bone, which is impaired by the underlying disease. Pathologic fractures can be caused by a variety of local and systemic diso...
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Article
Open AccessInfluence of osteogenic stimulation and VEGF treatment on in vivo bone formation in hMSC-seeded cancellous bone scaffolds
Tissue engineering approaches for reconstruction of large bone defects are still technically immature, especially in regard to sufficient blood supply. Therefore, the aim of the present study was to investigat...
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Article
Open AccessA popliteal giant synovial osteochondroma mimicking a parosteal osteosarcoma
Both giant synovial osteochondroma and parosteal osteosarcoma are rare musculo-skeletal tumors, often localized in the vicinity of the knee. Misdiagnosis of a malignant bone tumor can entail fatal consequences...
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Article
Open AccessTibiofemoral and patellofemoral joint 3D-kinematics in patients with posterior cruciate ligament deficiency compared to healthy volunteers
The posterior cruciate ligament (PCL) plays an important role in maintaining physiological kinematics and function of the knee joint. To date mainly in-vitro models or combined magnetic resonance and fluorosco...
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Article
Open AccessPercutaneous core needle biopsy versus open biopsy in diagnostics of bone and soft tissue sarcoma: a retrospective study
Biopsy is a crucial step within the diagnostic cascade in patients with suspected bone or soft tissue sarcoma. Open biopsy is still considered the gold standard. However, recent literature suggests similar res...
