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Article
Open AccessUSP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis
Neuroblastoma (NB) is a common pediatric cancer and contributes to more than 15% of all pediatric cancer-related deaths. Unlike adult tumors, recurrent somatic mutations in NB, such as tumor protein 53 (p53) m...
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Article
Open AccessDirect effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation
Embryonal cancer can arise from postnatally persistent embryonal remnant or rest cells, which are uniquely characterized by the absence of p53 mutations. Perinatal overexpression of the MycN oncoprotein in emb...
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Chapter and Conference Paper
MVCT image quality and dose as change of jaw aperture size on a helical TomoTherapy
Recently, jaw size was changed from 4 mm aper- ture (J4) to 1 mm (J1) in TomoTherapy Hi-Art II® (TomoThe- rapy Inc., Madison, WI) to improve the longitudinal (IEC-Y) resolution of megavoltage computed tomograp...
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Article
Interspecific hybridization in the genus Paeonia (Paeoniaceae): Polymorphic sites in transcribed spacers of the 45S rRNA genes as indicators of natural and artificial peony hybrids
The ITS1-5.8S rDNA-ITS2 regions of 33 accessions belonging to 16 species and five natural and garden interspecific hybrids of the genus Paeonia L. were sequenced. Chromatograms of the peony hybrids demonstrated t...
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Article
2009 H1N1 influenza infection in Korean healthcare personnel
Healthcare personnel (HCP) can acquire influenza and transmit it to patients and other hospital staff. The aim of this study was to evaluate the attack rate of HCP by the 2009 H1N1 influenza virus during the 2...
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Article
Electrical and Optical Studies of the Organic Thin Film Devices Produced by Cluster Beam Deposition Methods
The neutral and ionized cluster beam deposition (NCBD and ICBD) methods have been applied to fabricate the new double-layer organic light emitting devices (OLEDs) with the structure of indium-tin-oxide (ITO)-c...
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Article
Electrochemical Impedance Spectroscopy to Assess Vascular Oxidative Stress
Vascular inflammatory responses are intimately linked with oxidative stress, favoring the development of pre-atherosclerotic lesions. We proposed that oxidized low density lipoprotein (oxLDL) and foam cell inf...
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Article
The origin of polyploid genomes of bluegrasses Poa L. and Gene flow between northern pacific and sub-Antarctic Islands
The involvement of present-day diploid bluegrass species in the formation of polyploid genomes was investigated using comparison of sequences of internal transcribed spacers ITS1 and ITS2, and the 5.8S rRNA seque...
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Article
Analysis of neck fractures from frontal collisions at low speeds
Neck fracture is a major cause of death in traffic accidents. This pattern of injury normally occurs in a frontal collision or overturn of a vehicle. This study investigates the case of a neck fracture from a ...
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Article
Open AccessVarious Quantum- and Nano-Structures by III–V Droplet Epitaxy on GaAs Substrates
We report on various self-assembled In(Ga)As nanostructures by droplet epitaxy on GaAs substrates using molecular beam epitaxy. Depending on the growth condition and index of surfaces, various nanostructures c...
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Article
The unique genome of two-chromosome grasses Zingeria and Colpodium, its origin, and evolution
Chromosome C-banding and two-color fluorescent in situ hybridization (FISH) were used to compare the chromosomes, to identify the chromosomal localization of the 45S and 5S rRNA genes, and to analyze the seque...
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Article
A genetic mouse model for metastatic lung cancer with gender differences in survival
Lung cancer is a devastating disease with poor prognosis. The design of better therapies for lung cancer patients would be greatly aided by good mouse models that closely resemble the human disease. Unfortunat...
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Article
Genomic Configuration of the Autotetraploid Oat Species Avena macrostachya Inferred from Comparative Analysis of ITS1 and ITS2 Sequences: on the Oat Karyotype Evolution during the Early Events of the Avena Species Divergence
To examine the genomic configuration of Avena macrostachya, internal transcribed spacers, ITS1 and ITS2, as well as nuclear 5.8S rRNA genes from three oat species with AsAs karyotype (A. wiestii, A. hirtula, and
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Article
Avermectin: biochemical and molecular basis of its biosynthesis and regulation
Avermectin and its analogues, produced by Streptomyces avermitilis, are major commercial antiparasitic agents in the field of animal health, agriculture, and human infections. They are 16-membered pentacyclic la...
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Chapter
Dietary Taurine Intake and Serum Taurine Levels of Women on Jeju Island
The purpose of this study was to investigate the dietary taurine intake and serum taurine levels of women on Jeju Island in Korea. Sixty six married women aged 43.5 ± 7.1 volunteered for this study: 34 from th...
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Chapter
Effect of α-Tocopherol and Taurine Supplementation on Oxidized LDL Levels of Middle Aged Korean Women During Aerobic Exercise
The risk factors of atherosclerosis have been reported as elevated levels of total cholesterol and low density lipoprotein-cholesterol (LDL-C) and low levels of high density lipoprotein-cholesterol (HDL-C) in ...
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Article
Chromosome CPD(PI/DAPI)- and CMA/DAPI-Banding Patterns in Allium cepa L.
Chromosome banding patterns of Allium cepa L. were obtained by using fluorescent dye combinations chromomycin A3 (CMA) + 4",6-diamidino-2-phenylindole (DAPI), DAPI + actinomycin D (AMD) and propidium iodide (PI) ...
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Chapter
Taurine Intake and Excretion in Patients Undergoing Long Term Enterel Nutrition
The purpose of this study was to investigate whether serum concentration and urinary excretion of taurine are influenced by marginal taurine intake. Twenty one male patients (75 to 95 years old), suffering fro...
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Article
Extent of disease and results of adjuvant radiotherapy after radical hysterectomy and pelvic lymphadenectomy in the treatment of stage IB, IIA, and IIB cervical carcinoma
Background. To identify variable prognostic factors and analyze failure patterns in uterine cervix cancer after radical operation and adjuvant radiotherapy, a retrospective analysis was undertaken.
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Article
Test Methods for Characterizing Piezoelectric Thin Films
Two experimental techniques for quantifying MEMS-relevant material constants of piezoelectric thin films are presented. The first is an improved version of our recently developed ‘plank method.’ This technique...