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Impact of Endurance Exercise Training in the Fasted State on Muscle Biochemistry and Metabolism in Healthy Subjects: Can These Effects be of Particular Clinical Benefit to Type 2 Diabetes Mellitus and Insulin-Resistant Patients?
Exercise training intervention is a cornerstone in the care of type 2 diabetes mellitus (T2DM) and insulin resistance (IR), and it is pursued in order to optimize exercise interventions for these patients. In ...
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Article
Open AccessCirculating classical monocytes are associated with CD11c+ macrophages in human visceral adipose tissue
Immune cell accumulation in adipose tissue (AT) is associated with the development of AT inflammation, resulting in metabolic dysfunction. Circulating immune cell patterns may reflect immune cell accumulation ...
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Article
Chronotropic Incompetence During Exercise in Type 2 Diabetes: Aetiology, Assessment Methodology, Prognostic Impact and Therapy
During incremental exercise tests, chronotropic incompetence (CI), which is the inability of the heart rate (HR) to rise in proportion to an increase in metabolic demand, is often observed in patients with typ...
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Article
Open AccessTelerehab III: a multi-center randomized, controlled trial investigating the long-term effectiveness of a comprehensive cardiac telerehabilitation program - Rationale and study design
Telerehabilitation has been proposed as an adjunct/alternative to standard center-based cardiac rehabilitation. Two recent systematic reviews showed non-inferiority and/or superiority of this remote approach f...
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Article
Open AccessReliability and Validity of the Dutch Physical Activity Questionnaires for Children (PAQ-C) and Adolescents (PAQ-A)
This study was designed to validate the Dutch Physical Activity Questionnaires for Children (PAQ-C) and Adolescents (PAQ-A).
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Article
Open AccessMandatory oral glucose tolerance tests identify more diabetics in stable patients with chronic heart failure: a prospective observational study
Many patients with chronic heart failure (CHF) are believed to have unrecognized diabetes, which is associated with a worse prognosis. This study aimed to describe glucose tolerance in a general stable CHF pop...
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Article
Response to letter from RJ Shephard ‘Problems of medical supervision and physiological validity encountered with fixed-rate step tests’
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Article
Are fixed-rate step tests medically safe for assessing physical fitness?
Maximal oxygen uptake (VO2max) can be predicted by fixed-rate step tests. However, it remains to be analyzed as to what exercise intensities are reached during such tests to address medical safety. In this study,...
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Article
The Impact of Training Modalities on the Clinical Benefits of Exercise Intervention in Patients with Cardiovascular Disease Risk or Type 2 Diabetes Mellitus
Exercise training intervention represents an effective means to reduce adipose tissue mass, improve glycaemic control and increase whole-body oxygen uptake capacity (V̇O2peak) in obesity, metabolic syndrome, type...
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Article
Open AccessPlasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients
Elevated plasma free fatty acid (FFA), inflammatory marker, and altered adipokine concentrations have been observed in obese type 2 diabetes patients. It remains unclear whether these altered plasma concentrat...
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Article
Low agreement of ventilatory threshold between training modes in cardiac patients
In cardiac rehabilitation, different endurance exercises such as walking and cycling are often performed. The training intensity for these modes is determined from a single treadmill or bicycle test by ventila...
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Article
The Effects of Exercise Training on Fat-Mass Loss in Obese Patients During Energy Intake Restriction
Dietary restriction combined with endurance exercise training represents an effective strategy to promote weight loss and reduce fat mass in obese patients. Exercise programmes without dietary restriction are ...
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Article
Rehabilitation in Cardiac Patients
This article discusses the effects of training in cardiac rehabilitation and describes the influence of various training modalities on the evolution of exercise capacity in cardiac patients. Both home- and hos...
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Hoofdstuk 8 Effecten van cardiale revalidatie op inspanningscapaciteit: invloeden van trainingsmodaliteiten
Cardiale revalidatie leidt tot een belangrijke toename van de belastbaarheid. Hierbij dient men onderscheid te maken tussen de maximale en de aërobe belastbaarheid. Dit is belangrijk omdat deze twee vormen van...