183 Result(s)
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Di **e
Medicine & Public Health
Medicine/Public Health, general
Pediatrics
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Article
Pediatric obesity-related non-alcoholic fatty liver disease: waist-to-height ratio best anthropometrical predictor
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder in pediatric obesity. Our study aims to identify a predictive anthropometrical measure for NAFLD in obese children.
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Congenital chloride diarrhea clinical features and management: a systematic review
Congenital chloride diarrhea (CLD) is a rare autosomal recessive disorder characterized by watery diarrhea with a high level of fecal Cl−, metabolic alkalosis, and electrolyte alterations. Several intestinal and ...
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Article
Zinc levels in neonatal life influence long-term neurodevelopment
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Influence of different breast expression techniques on human colostrum macronutrient concentrations
To evaluate the effects of breast expression methods on macronutrient and caloric concentrations in human colostrum.
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Open AccessIntrauterine inflammation induced white matter injury protection by fibrinogen-like protein 2 deficiency in perinatal mice
White matter injury (WMI) induced by intrauterine inflammation can cause adverse neurological outcomes. Fibrinogen-like protein 2 (FGL2)/fibroleukin is an important trigger of inflammatory responses and is inv...
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A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children
At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of ...
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Article
Urinary Cystatin-C, a marker to assess and monitor neonatal kidney maturation and function: validation in twins
Nephrogenesis is a complex process of nephron formation and maturation that can be compromised by preterm delivery and intrauterine growth restriction. This study aimed to evaluate and compare urinary Cys-C le...
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Open AccessRole of feeding strategy bundle with acid-suppressive therapy in infants with esophageal acid reflux exposure: a randomized controlled trial
To test the hypothesis that a feeding bundle concurrent with acid suppression is superior to acid suppression alone in improving gastroesophageal reflux disease (GERD) attributed-symptom scores and feeding out...
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Differentiating esophageal sensitivity phenotypes using pH–impedance in intensive care unit infants referred for gastroesophageal reflux symptoms
To identify esophageal sensitivity phenotypes relative to acid (SAcid), bolus (SBolus), acid and bolus (SAcid+Bolus), and none (SNone) exposures in infants suspected with gastroesophageal reflux disease (GERD).
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Open AccessCOVID-19 PICU guidelines: for high- and limited-resource settings
Fewer children than adults have been affected by the COVID-19 pandemic, and the clinical manifestations are distinct from those of adults. Some children particularly those with acute or chronic co-morbidities ...
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Congenital cytomegalovirus infection and audiological follow-up: electrophysiological auditory threshold before 3 months of age as a predictor of hearing outcome at 3 years of age
We aimed to evaluate whether electrophysiological auditory thresholds (EATs) before 3 month of age, as assessed by the auditory brainstem responses (ABR) test and the auditory steady state responses (ASSR) tes...
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Transmembrane 6 superfamily member 2 167K allele improves renal function in children with obesity
The transmembrane 6 superfamily member 2 (TM6SF2) E167K polymorphism influences estimated glomerular filtration rate (eGFR) in adults without diabetes and without obesity. We aimed exploring the impact of this po...
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Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine
Necrotizing enterocolitis (NEC), a necrotic inflammation of the intestine, represents a major health problem in the very premature infant. Although prevention is difficult, the combination of ingestion of mate...
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A novel delivery system for supraglottic atomization allows increased lung deposition rates of pulmonary surfactant in newborn piglets
Earlier attempts to deliver effective lung doses of surfactant by aerosolization were unsuccessful, mostly because of technical shortcomings. We aimed at quantifying the lung deposition of poractant alfa with ...
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Electroencephalographic functional connectivity in extreme prematurity: a pilot study based on graph theory
Connectivity studies based on functional magnetic resonance imaging (MRI) provided new insights in neonatal brain development but cannot be performed at bedside in the clinical setting. The electroencephalogra...
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Wolfram syndrome 1 in the Italian population: genotype–phenotype correlations
We studied 45 patients with Wolfram syndrome 1 (WS1) to describe their clinical history and to search for possible genotype–phenotype correlations.
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Pre-Vent: the prematurity-related ventilatory control study
The increasing incidence of bronchopulmonary dysplasia in premature babies may be due in part to immature ventilatory control, contributing to hypoxemia. The latter responds to ventilation and/or oxygen therap...
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Open AccessGenetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesity
To comprehensively explore metabolic and genetic contributors to liver fat accumulation in overweight/obese children.
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Article
Neonatal intermittent hypoxemia events are associated with diagnosis of bronchopulmonary dysplasia at 36 weeks postmenstrual age
Bronchopulmonary dysplasia (BPD) is a chronic lung disease and major pulmonary complication after premature birth. We have previously shown that increased intermittent hypoxemia (IH) events have been correlate...
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Early inspired oxygen and intermittent hypoxemic events in extremely premature infants are associated with asthma medication use at 2 years of age
Extremely premature infants are at risk for childhood wheezing. Early respiratory support and intermittent hypoxemia (IH) events may be associated with adverse breathing outcomes.
