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Chapter
Possible Overcoming of Tumor Hypoxia with Adaptive Hypofractionated Radiosurgery of Large Brain Metastases: A Biological Modeling Study
Objective: The present biological modeling study evaluated possible application of adaptive hypofractionated stereotactic radiosurgery (HSRS), which involves escalation of the prescription dose according to the g...
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Article
Open AccessGlioma consensus contouring recommendations from a MR-Linac International Consortium Research Group and evaluation of a CT-MRI and MRI-only workflow
This study proposes contouring recommendations for radiation treatment planning target volumes and organs-at-risk (OARs) for both low grade and high grade gliomas.
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Chapter and Conference Paper
Deep Generative Model for Synthetic-CT Generation with Uncertainty Predictions
MR-only radiation treatment planning is attractive due to the superior soft tissue definition of MRI as compared to CT, and the elimination of the uncertainty introduced by CT-MRI registration. To facilitate M...
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Article
Open AccessQuantitative MRI Biomarkers of Stereotactic Radiotherapy Outcome in Brain Metastasis
About 20–40% of cancer patients develop brain metastases, causing significant morbidity and mortality. Stereotactic radiation treatment is an established option that delivers high dose radiation to the target ...
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Chapter
Stereotactic Body Radiation Therapy (SBRT) for Spinal Tumors
Bony metastases frequently involve the spine and can cause significant morbidity with pain and neurologic compromise. A shift toward hypofractionated radiotherapy delivered over 1 to 5 fractions has taken plac...
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Chapter
Spinal Cord Tolerance and Risk of Radiation Myelopathy
Radiation myelopathy (RM) is one of the most feared complications of radiation therapy.
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Article
Open AccessCost-effectiveness of novel vaccines for tuberculosis control: a decision analysis study
The development of a successful new tuberculosis (TB) vaccine would circumvent many limitations of current diagnostic and treatment practices. However, vaccine development is complex and costly. We aimed to as...
