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Chapter
Considerations and Criteria for the Incorporation of Mechanistic Sublethal Endpoints into Environmental Risk Assessment for Biologically Active Compounds
Awareness about the presence and unintended consequence of biologically active organic contaminants in the environment was largely borne out of seminal observational works concerning pesticides in the early 19...
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Chapter
Human Pharmaceuticals in the Aquatic Environment: A Review of Recent Toxicological Studies and Considerations for Toxicity Testing
Widespread detection of human pharmaceuticals in the environment, ranging between ng/L and mg/L levels in surface waters and effluents and ng/kg to mg/kg levels in aquatic and terrestrial organisms, has caused...
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Chapter
Human Health Risk Assessment for Pharmaceuticals in the Environment: Existing Practice, Uncertainty, and Future Directions
Globally, several thousand substances are produced for pharmaceutical and biomedical applications in humans. The production tonnage of these compounds is astronomical, ranging to hundreds of tons annually. Bas...
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Article
River–reservoir transition zones are nitrogen fixation hot spots regardless of ecosystem trophic state
Reservoir hydrodynamics may create heterogeneity in nitrogen (N) fixation along the riverine–transition–lacustrine gradient. In particular, N fixation may be highest in reservoir transition zones where phytopl...
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Article
Physical Factors Control Phytoplankton Production and Nitrogen Fixation in Eight Texas Reservoirs
We compared regression tree analyses and multiple linear regression models to explore the relative importance of physical factors, land use, and water quality in predicting phytoplankton production and N2 fixatio...
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Chapter
Aquatic Plants Exposed to Pharmaceuticals: Effects and Risks
The discovery of therapeutic medicinal products has historically been largely accidental, through trial and error involving observation of the therapeutic effects of “naturally” produced compounds such as peni...
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Article
Physiological and Reproductive Effects of Beta Adrenergic Receptor Antagonists in Daphnia magna
Although pharmaceuticals are increasingly found in surface waters, environmental levels of many of these compounds are not acutely toxic to model test organisms. Prior to conducting appropriate ecological risk...
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Article
Water Quality of Effluent-dominated Ecosystems: Ecotoxicological, Hydrological, and Management Considerations
In arid and semi-arid regions of the southwestern United States and other parts of the world, flows of historically ephemeral streams are now perennially dominated by municipal and/or industrial effluent disch...
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Article
Reproductive Assessment of Japanese Medaka (Oryzias latipes) Following a Four-Week Fluoxetine (SSRI) Exposure
The occurrence of environmental pharmaceutical products has recently received considerable attention, but impacts on the aquatic environment are largely unknown. Fluoxetine is a widely prescribed antidepressan...
