-
Article
The pathogenesis, diagnosis and treatment of Raynaud phenomenon
Recent advances in pathogenesis and diagnosis of Raynaud phenomenon have driven, and are driving, new therapeutic strategies for this phenomenon. In this Review, Ariane Herrick provides an update of the pathog...
-
Chapter
Raynaud’s Phenomenon
A 38-year-old female patient presented to the rheumatology clinic with a 3-week history of a painful fingertip ulcer. The pain was so severe that it was kee** her awake at night. For 20 years (since her teen...
-
Chapter
A 22-Year-Old Woman with Raynaud’s Phenomenon but No Other Symptoms and No Abnormalities on Examination
Raynaud’s phenomenon, episodic color change of the fingers usually in response to cold exposure, can be either primary (idiopathic: PRP) or secondary to an underlying disease or condition, for example, to a sy...
-
Article
A local approach to Raynaud phenomenon
The current treatment options for Raynaud phenomenon are often ineffective and can have undesirable adverse effects. Topical, or transdermal, treatments that increase digital blood flow without systemic advers...
-
Article
Genetic epidemiology: Systemic sclerosis
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised phenotypically by fibrosis and ischaemic atrophy. Its aetiology is most likely multifactorial. A genetic predisposition to the ...
-
Chapter and Conference Paper
Microvascular Dynamics in the Nailfolds of Scleroderma Patients Studied Using Na-Fluorescein dye
Dynamic microscopy of the nailfold capillaries using Na- fluorescein dye can be used to assess the condition of the peripheral circulation of Scleroderma patients, yielding more information than simple morphol...
