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Open AccessTargeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts
Targeted RNA-Seq combines next-generation sequencing with capture of sequences from a relevant subset of a transcriptome. When testing by capturing sequences from a tumor cDNA library by hybridization to oligo...
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Article
Open AccessALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads
We demonstrate that genome sequences approaching finished quality can be generated from short paired reads. Using 36 base (fragment) and 26 base (jum**) reads from five microbial genomes of varied GC composi...
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Article
Open AccessInsights from the genome of the biotrophic fungal plant pathogen Ustilago maydis
Ustilago maydis is an important fungal pathogen of maize, causing corn smut. It is well adapted to its host and proliferates in living plant tissue without inducing a defence response. The genome sequence of U. m...
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Article
Correction: Corrigendum: DNA sequence and analysis of human chromosome 18
Nature 437, 551–555 (2005) doi:10.1038/nature03983 The name of Keith O'Neill was accidentally omitted from the published author list. He is at the first affiliation in the address list.
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Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophilagenome
It is widely accepted that comparative sequence data can aid the functional annotation of genome sequences; however, the most informative species and features of genome evolution for comparison remain to be de...
