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252 Result(s)
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Chapter and Conference Paper
A Bearing Fault Diagnosis Method Based on VMD-HPE
Since rolling bearings operate in complex and harsh conditions with high speed and heavy load for a long time, their fault signals have the problems of difficulty in feature extraction and low diagnostic accur...
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Article
A systematic review and meta-analysis of prognostic indicators in patients with head and neck malignancy treated with immune checkpoint inhibitors
Tumor immunotherapy has recently emerged as a crucial focal point in oncology treatment research. Among tumor immunotherapy approaches, tumor immune checkpoint inhibitors (ICIs) have attracted substantial atte...
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Article
Open AccessLOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
Pathological cardiac hypertrophy (CH) is featured by myocyte enlargement and cardiac malfunction. Multiple signaling pathways have been implicated in diverse pathological and physiological processes in CH. How...
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Article
Open AccessThe analysis of the genotype of Sapovirus outbreaks in Zhejiang Province
Sapovirus (SaV) infection is increasing globally. Concurrently, several SaV-outbreaks were observed in children of Zhejiang province, China, in recent years, In this study, the genotypes of Sapovirus from seve...
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Article
Open AccessDiscordance between chromatin accessibility and transcriptional activity during the human primed-to-naïve pluripotency transition process
Naïve pluripotent state can be obtained by several strategies from various types of cells, in which the cell fate roadmap as well as key biological events involved in the journey have been described in detail....
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Article
Open AccessFNIP1 abrogation promotes functional revascularization of ischemic skeletal muscle by driving macrophage recruitment
Ischaemia of the heart and limbs attributable to compromised blood supply is a major cause of mortality and morbidity. The mechanisms of functional angiogenesis remain poorly understood, however. Here we show ...
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Article
Open AccessGamma-glutamyl transpeptidase and indirect bilirubin may participate in systemic inflammation of patients with psoriatic arthritis
Previous studies have suggested that systemic metabolic abnormalities are closely related to psoriatic arthritis (PsA). Gamma-glutamyl transpeptidase (GGT) and indirect bilirubin (IBIL), two essential active s...
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Article
Open AccessAssociations between vision impairment and multimorbidity among older Chinese adults: results from the China health and retirement longitudinal study
Although several studies have reported the relationship between vision impairment (VI) and multimorbidity in high-income countries, this relationship has not been reported in low- and middle-income countries. ...
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Article
Open AccessAssociation between ICU admission (neutrophil + monocyte)/lymphocyte ratio and 30-day mortality in patients with sepsis: a retrospective cohort study
Sepsis is an important public health issue, and it is urgent to develop valuable indicators to predict the prognosis of sepsis. Our study aims to assess the predictive value of ICU admission (Neutrophil + Mono...
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Article
Open AccessImportation of a novel Indian Ocean lineage carrying E1-K211E and E2-V264A of Chikungunya Virus in Zhejiang Province, China, in 2019
The chikungunya virus (CHIKV) is widespread. In Zhejiang province, China, CHIKV infection is often associated with travelers from tropical and subtropical countries. In the present study, three CHIKV isolates ...
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Article
METTL3 facilitates multiple myeloma tumorigenesis by enhancing YY1 stability and pri-microRNA-27 maturation in m6A-dependent manner
Multiple myeloma (MM) is a pernicious plasma cell disorder and has a poor prognosis. N6-methyladenosine (m6A) is an abundant epigenetic RNA modification and is important in cancer progression. Nevertheless, the f...
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Article
Sulfonic acid functionalized monolithic column for high selectivity capillary electrochromatography separation
A new nano-scale spherical vinyl-functionalized covalent organic polymer (TAPT-DVA-COP) with uniform sizes around 300 nm was initially constructed using 2,5-divinyl-1,4-benzaldehyde (DVA) and 2,4,6-tris(4-amin...
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Article
Open AccessSociodemographic features associated with the MoCA, SPPB, and GDS scores in a community-dwelling elderly population
An accurate evaluation of cognitive function, physical health, and psychological health is fundamental for assessing health problems in the elderly population, and it is important to identify the necessity of ...
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Article
Open AccessAnnexin A9 promotes cell proliferation by regulating the Wnt signaling pathway in colorectal cancer
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality worldwide. Expression of Annexin A9 (ANXA9), a member of the annexin A family, is upregulated in CRC. However, the molecular rol...
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Article
Open AccessVitamin D and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study
A prospective study of multiple small samples found that idiopathic pulmonary fibrosis (IPF) is often accompanied by a deficiency in Vitamin D levels. However, the causal relationship between the two remains t...
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Article
Open AccessLoss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development
The communication between tumor cells and tumor microenvironment plays a critical role in cancer development. Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and tak...
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Article
Open AccessCongenital coralliform cataract is the predominant consequence of a recurrent mutation in the CRYGD gene
Congenital cataract is a leading cause of treatable childhood blindness and both clinically and genetically heterogeneous. Among the already characterized phenotypes, coralliform cataract is a rare special for...
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Article
Describing function method with pointwise balancing in time domain for periodic responses of non-smooth self-excited system
This paper proposes a describing function method with pointwise balancing in time domain (DFPB), to solve periodic responses semi-analytically of self-excited systems with non-smooth and/or complicated nonline...
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Article
Modulating nanostructures in metals by magneton sputtering
Here, we report an effective nanostructures modulation strategy by W alloying and annealing treatment in Cu films deposited by magnetron sputtering. The as-deposited Cu and Cu–W films exhibit nanograins with c...
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Article
Proteolytic rewiring of mitochondria by LONP1 directs cell identity switching of adipocytes
Mitochondrial proteases are emerging as key regulators of mitochondrial plasticity and acting as both protein quality surveillance and regulatory enzymes by performing highly regulated proteolytic reactions. H...