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Article
APR-246 triggers ferritinophagy and ferroptosis of diffuse large B-cell lymphoma cells with distinct TP53 mutations
TP53 mutations correlate with inferior survival in many cancers. APR-246 is a compound to shift mutant p53 and exhibits anti-cancer effects. Among its effects, APR-246 facilitates the binding of restored p53 m...
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Article
SND1 confers chemoresistance to cisplatin-induced apoptosis by targeting GAS6-AKT in SKOV3 ovarian cancer cells
Platinum-based (especially cisplatin) chemotherapy is the main treatment after surgery for ovarian cancer. Although the initial treatment is effective, chemotherapy resistance develops rapidly. Therefore, chem...
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Article
Open AccessvChecker: an application-level demand-based co-scheduler for improving the performance of parallel jobs in Xen
Big data analysis requires the speedup of parallel computing. However, in the virtualized systems, the power of parallel computing is not fully exploited due to the limit of current VMM schedulers. Xen, one of...
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Article
Open AccessContention-aware prediction for performance impact of task co-running in multicore computers
In this paper, we investigate the influential factors that impact on the performance when the tasks are co-running on a multicore computers. Further, we propose the machine learning-based prediction framework ...
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Article
Enhanced dielectric permittivity and breakdown strength of poly(vinylidene fluoride) nanocomposites containing core–shell BaTiO3@TiO2 nanofibers
Dielectric capacitor has been rapidly developed in recent years, and the ceramics nanofibers/polymer nanocomposites with improved dielectric properties have huge potential in exploitation and application. In t...
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Article
Electroacupuncture enhances resting-state functional connectivity between dorsal caudate and precuneus and decreases associated leptin levels in overweight/obese subjects
Electroacupuncture (EA) is a safe and effective method for treating obesity. However, how it modulates reward-related brain activity/functional connectivity and gut hormones remains unclear. We employed restin...
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Article
Morphology prediction of 1,3,5,7-tetranitro-1,3,5,7-tetrazocane (HMX) crystal in dimethyl sulfoxide (DMSO) solvent with different models using molecular dynamics simulation
The interface interaction between DMSO solution and HMX crystal was simulated by molecular dynamics (MD) method, and the morphology of HMX in DMSO solvent was predicted through the occupancy model and attachme...
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Article
Combination of the mutations for improving activity of TEV protease in inclusion bodies
Tobacco etch virus protease (TEVp) is an enzymatic reagent to remove fusion tag, but additional purification steps are required for removing the TEVp after cleavage reaction is finished. Use of carrier-free an...
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Article
Open AccessDevelopment of a biomechanical model for dynamic occlusal stress analysis
The use of traditional finite element method (FEM) in occlusal stress analysis is limited due to the complexity of musculature simulation. The present purpose was to develop a displacement boundary condition (...
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Article
Experimental study on the influence of soluble salt content on unsaturated mechanical characteristics of undisturbed Ili loess
Due to the perennial influence by west wind climate, the loess in Ili, China, is obviously different from that in the loess plateau of the monsoon area, showing the characteristics of large collapsible deforma...
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Article
Open Access4210 Da and 1866 Da polypeptides as potential biomarkers of liver disease progression in hepatitis B virus patients
HBV infection is recognized as a serious global health problem, and hepatitis B virus infection is a complicated chronic disease leading to liver cirrhosis (LC) and hepatocellular carcinoma (HCC). New biochemi...
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Article
Open AccessEffect of sowing proportion on above- and below-ground competition in maize–soybean intercrops
The relative contribution of above- and below-ground competition to crop yield under intercrop** systems is critical to understanding the mechanisms of improved yield. Changes in the content of above- and be...
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Article
Open AccessGenetic expression and mutational profile analysis in different pathologic stages of hepatocellular carcinoma patients
The clinical pathologic stages (stage I, II, III-IV) of hepatocellular carcinoma (HCC) are closely linked to the clinical prognosis of patients. This study aims at investigating the gene expression and mutatio...
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Chapter and Conference Paper
Control of Pneumatic Artificial Muscles with SNN-based Cerebellar-Like Model
Soft robotics technologies have gained growing interest in recent years, which allows various applications from manufacturing to human-robot interaction. Pneumatic artificial muscle (PAM), a typical soft actua...
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Article
Long-term outcomes of 172 children with severe aplastic anemia treated with rabbit antithymocyte globulin and cyclosporine
This study retrospectively analyzed the clinical outcome of 172 children with newly diagnosed severe aplastic anemia (SAA) between January 2008 and April 2018, who received rabbit antithymocyte globulin (ATG) ...
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Article
Open AccessDifferential genetic mutations of ectoderm, mesoderm, and endoderm-derived tumors in TCGA database
In terms of biological behavior, gene regulation, or signaling pathways, there is a certain similarity between tumorigenesis and embryonic development of humans. Three germ layer structure exhibits the distinc...
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Article
Electroacupuncture reduces posterior cingulate cortex activation and functional connectivity during food cue stimulation in overweight/obese subjects
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Article
Design and analysis of a whole-body controller for a velocity controlled robot mobile manipulator
Mobile manipulators, which are intrinsically redundant when the manipulator and mobile base are moving together, are known for their capabilities to carry out multiple tasks at the same time. This paper presen...
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Article
Open AccessHarnessing C/N balance of Chromochloris zofingiensis to overcome the potential conflict in microalgal production
Accumulation of high-value products in microalgae is not conducive with rapid cell growth, which is the potential conflict in microalgal production. Overcoming such conflict faces numerous challenges in compre...
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Chapter and Conference Paper
Face Anti-spoofing with a Noise-Attention Network Using Color-Channel Difference Images
The wide deployment of face recognition systems has raised serious concern on its security level. One of the most prominent threats is the presentation attack, which attempts to fool the system in the absence ...
