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    Article

    A DNA-based fluorescent probe maps NOS3 activity with subcellular spatial resolution

    Nitric oxide synthase 3 (NOS3) produces the gasotransmitter nitric oxide (NO), which drives critical cellular signaling pathways by S-nitrosylating target proteins. Endogenous NOS3 resides at two distinct subcell...

    Maulik S. Jani, Junyi Zou, Aneesh T. Veetil, Yamuna Krishnan in Nature Chemical Biology (2020)

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    Article

    Three functional variants were identified to affect RPS24 expression and significantly associated with risk of colorectal cancer

    GWAS-identified 10q22.3 loci with lead SNP rs704017 are significantly associated with CRC risk in both Asian and European populations. However, the functional mechanism of this region is unclear. In this study...

    Danyi Zou, Hongli Zhang, Juntao Ke, Jiaoyuan Li, Ying Zhu in Archives of Toxicology (2020)

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    Chapter and Conference Paper

    An Automated Online Spam Detector Based on Deep Cascade Forest

    With the development of internet communication, spam is quite ubiquitous in our daily life. It not only disturbs users, but also cms. Although there exists many methods of spam detection in both the area of ...

    Kangyang Chen, **nyi Zou, **ngguo Chen, Huihui Wang in Science of Cyber Security (2019)

  4. Article

    Open Access

    Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations

    Germline coding variants have not been systematically investigated for pancreatic ductal adenocarcinoma (PDAC). Here we report an exome-wide investigation using the Illumina Human Exome Beadchip with 943 PDAC ...

    Jiang Chang, Jianbo Tian, Ying Zhu, Rong Zhong, Kan Zhai in Nature Communications (2018)

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    Article

    Exome-wide analyses identify low-frequency variant in CYP26B1 and additional coding variants associated with esophageal squamous cell carcinoma

    Genome-wide association studies have identified common variants associated with risk of esophageal squamous cell carcinoma (ESCC). However, these common variants cannot explain all heritability of ESCC. Here w...

    Jiang Chang, Rong Zhong, Jianbo Tian, Jiaoyuan Li, Kan Zhai, Juntao Ke in Nature Genetics (2018)

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    Article

    Determination of AR-42 enantiomeric purity by HPLC on chiral stationary phase

    A sensitive and accurate liquid chromatographic method for the determination of AR-42 enantiomeric purity has been developed and validated. Baseline separation with a resolution higher than 1.9 was accomplishe...

    Ai** Fang, Yue Zhang, Jiang Shen, Shi** Sun in Journal of the Iranian Chemical Society (2017)

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    Article

    Improved visible-light photocatalytic properties of ZnFe2O4 synthesized via sol-gel method combined with a microwave treatment

    ZnFe2O4(ZFO) was synthesized via a sol-gel method firstly, then the ZFO was irradiated with microwave treatment to obtain M-ZFO using NH4Cl as dispersant for 10 min to improve the photocatalytic activity. Large p...

    **g Feng, Yuting Wang, Linyi Zou, Bowen Li in Chemical Research in Chinese Universities (2015)

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    Article

    Distinct function of androgen receptor coactivator ARA70α and ARA70β in mammary gland development, and in breast cancer

    Steroid receptor coactivators are important in regulating the function of the receptors in endocrine organ development and in cancers, including breast. Androgen receptor (AR) coactivator ARA70, was first iden...

    **nyu Wu, Fei Chen, Aysegul Sahin in Breast Cancer Research and Treatment (2011)

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