43 Result(s)
within
**n-feng Ding
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessDevelopment and Validation of a Three-gene Prognostic Signature for Patients with Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related death worldwide, because recurrence often occurs in most HCC patients undergoing hepatectomy. It is necessary to identify patients with hig...
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Article
Open AccessSrc-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
This study aimed to investigate the role of src-homology protein tyrosine phosphatase-1 (SHP-1)–signal transducer and activator of transcription 3 (STAT3) pathway in liver fibrogenesis and the anti-fibrotic ef...
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Article
Open AccessA parameterized model for mean urinary inflow rate and its preliminary application in radiotherapy for cervical cancer
Forty-nine patients with stage IIb cervical cancer were included to investigate the changes in bladder volume in response to different approaches to maintaining consistent bladder filling. The impacts of age (P ...
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Open AccessLow level of swiprosin-1/EFhd2 in vestibular nuclei of spontaneously hypersensitive motion sickness mice
Susceptibility to motion sickness (MS) varies considerably among humans. However, the cause of such variation is unclear. Here, we used a classical genetic approach to obtain mouse strains highly sensitive and...
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Open AccessIdentification and expression analysis of an olfactory receptor gene family in green plant bug Apolygus lucorum (Meyer-Dür)
Olfactory receptors are believed to play a central role in insects host-seeking, mating, and ovipositing. On the basis of male and female antennal transcriptome of adult Apolygus lucorum, a total of 110 candidate...
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Open AccessCombining Exosomes Derived from Immature DCs with Donor Antigen-Specific Treg Cells Induces Tolerance in a Rat Liver Allograft Model
Allograft tolerance is the ultimate goal in the field of transplantation immunology. Immature dendritic cells (imDCs) play an important role in establishing tolerance but have limitations, including potential ...
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Article
Nodeless pairing in superconducting copper-oxide monolayer films on Bi2Sr2CaCu2O8+δ
The pairing mechanism of high-temperature superconductivity in cuprates remains the biggest unresolved mystery in condensed matter physics. To solve the problem, one of the most effective approaches is to inv...
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Open AccessIntegrating Epigenomic Elements and GWASs Identifies BDNF Gene Affecting Bone Mineral Density and Osteoporotic Fracture Risk
To identify susceptibility genes for osteoporosis, we conducted an integrative analysis that combined epigenomic elements and previous genome-wide association studies (GWASs) data, followed by validation at po...
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Open AccessPostnatal dysregulation of Notch signal disrupts dendrite development of adult-born neurons in the hippocampus and contributes to memory impairment
Deficits in the Notch pathway are involved in a number of neurologic diseases associated with mental retardation or/and dementia. The mechanisms by which Notch dysregulation are associated with mental retardat...
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Open AccessEffect of Body mass index on the performance characteristics of PSA-related markers to detect prostate cancer
To examine whether the predictive performance of prostate-specific antigen (PSA) and PSA-related markers for prostate cancer (PCa) is modified by body mass index (BMI). Patients with a PSA 2–10 ng/mL who under...
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Article
Open AccessFatigue-induced Orosomucoid 1 Acts on C-C Chemokine Receptor Type 5 to Enhance Muscle Endurance
Understanding and managing fatigue is a significant challenge in clinic and society. In attempting to explore how the body responds to and regulates fatigue, we found in rodent fatigue models that orosomucoid ...
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Open AccessThe TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development
TLRs (Toll-like receptors) play an important role in the initiation of innate immune responses against invading microorganisms. Although several TLRs have been reported to be involved in the innate immune resp...
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Article
Open AccessDevelopment and external validation of a prostate health index-based nomogram for predicting prostate cancer
To develop and externally validate a prostate health index (PHI)-based nomogram for predicting the presence of prostate cancer (PCa) at biopsy in Chinese men with prostate-specific antigen 4–10 ng/mL and norma...
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Article
Open AccessA novel UCS memory retrieval-extinction procedure to inhibit relapse to drug seeking
We recently reported that a conditioned stimulus (CS) memory retrieval-extinction procedure decreases reinstatement of cocaine and heroin seeking in rats and heroin craving in humans. Here we show that non-con...
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Open AccessVisualization of electrochemically driven solid-state phase transformations using operando hard X-ray spectro-imaging
In situ techniques with high temporal, spatial and chemical resolution are key to understand ubiquitous solid-state phase transformations, which are crucial to many technological applications. Hard X-ray spectro-...
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Open AccessHigh expression of MAGE-A9 correlates with unfavorable survival in hepatocellular carcinoma
Melanoma-associated antigens (MAGE)-A9 has been reported to play important roles in the development of human cancers. However, the association between MAGE-A9 expression and the clinicopathological characteris...
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Article
Open AccessEffect of BZG-4000, a novel multi-targeted kinase inhibitor with potent anticancer activity, on a hepatocellular carcinoma xenograft model
The present study was to synthesize a novel multi-targeted kinase inhibitor and evaluated its anticancer effects on a hepatocellular carcinoma xenograft model. In our study, in vivo efficacy was determined in nud...
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Article
Open AccessCompetitive Binding of Natural Amphiphiles with Graphene Derivatives
Understanding the transformation of graphene derivatives by natural amphiphiles is essential for elucidating the biological and environmental implications of this emerging class of engineered nanomaterials. Us...
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Open AccessPerformance of breast cancer screening methods and modality among Chinese women: a report from a society-based breast screening program (SBSP) in Shanghai
To evaluate the screening performance of individual and combined use of clinical breast examination, ultrasonography and mammography in Chinese women, we conducted a biennial breast cancer screening program am...
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Article
Features of left ventricular hypertrophy in patients with metabolic syndrome with or without comparable blood pressure: a meta-analysis
The prevalence of metabolic syndrome (MS) has been on the rise over the past few decades, and this is associated with an increased incidence of target organ damage such as left ventricular hypertrophy (LVH). T...
