146 Result(s)
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Article
Correlation between clinical characteristics and tinnitus severity in tinnitus patients of different sexes: an analytic retrospective study
This study aimed to explore whether sex is influences tinnitus severity and whether the risk factors for tinnitus severity are the same in tinnitus patients of different sexes.
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Article
Open AccessThe oral selective estrogen receptor degrader GDC-0810 (ARN-810) in postmenopausal women with hormone receptor-positive HER2-negative (HR + /HER2 −) advanced/metastatic breast cancer
GDC-0810 (ARN-810) is a novel, non-steroidal, orally bioavailable, selective estrogen receptor degrader (SERD) that potentially inhibits ligand-dependent and ligand-independent estrogen receptor (ER)-mediated ...
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Open AccessPrevalence and influence of hypouricemia on cardiovascular diseases in patients with rheumatoid arthritis
Serum uric acid (SUA) acts as an antioxidant and abnormally low SUA may raise the risk of develo** atherosclerotic disorders. There is a U-shaped association between SUA with cardiovascular diseases (CVDs) i...
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Colonic Malakoplakia with Retroperitoneal Extension Mimicking Advanced Colon Cancer
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Article
CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1
Abnormal regulation of centrosome components can induce chromosome instability and tumorigenesis. Centrosomal protein 63 (CEP63) is a vital member for assembling centrosome. Yet, the involvement of CEP63 in ca...
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Open AccessEarly prediction of noninvasive ventilation failure after extubation: development and validation of a machine-learning model
Noninvasive ventilation (NIV) has been widely used in critically ill patients after extubation. However, NIV failure is associated with poor outcomes. This study aimed to determine early predictors of NIV fail...
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Article
Open AccessImpact of the COVID-19 pandemic on congenital diaphragmatic hernia patients: a single-center retrospective study
To investigate the impact of COVID-19 on the treatment of children with congenital diaphragmatic hernia (CDH).
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Open AccessBerberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota
Trimethylamine-N-oxide (TMAO) derived from the gut microbiota is an atherogenic metabolite. This study investigates whether or not berberine (BBR) could reduce TMAO production in the gut microbiota and treat athe...
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Open AccessIs there a role for cementless primary stem in hip arthroplasty for early or late fixation failures of intertrochanteric fractures?
The choice of femur stems during the hip arthroplasty procedures for patients with treatment failure of intertrochanteric fractures (ITF) remains controversial. We aimed to compare the surgical complication an...
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Article
Effect of Electro-acupuncture on Vasomotor Symptoms in Rats with Acute Cerebral Infarction Based on Phosphatidylinositol System
To investigate the effect of electro-acupuncture (EA) on vasomotor symptoms in rats with acute cerebral infarction, by observing the changes in the expression of factors related to the phosphatidylinositol (PI...
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Article
Comparison of the prognosis of four different surgical strategies for proximal gastric cancer: a network meta-analysis
There is controversy regarding the long-term prognosis and short-term postoperative complications of different surgical strategies for proximal gastric cancer (PGC).
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Article
Open AccessAK098656: a new biomarker of coronary stenosis severity in hypertensive and coronary heart disease patients
AK098656 may be an adverse factor for coronary heart disease (CHD), especially in patients with hypertension. This study aimed to analyze the effect of AK098656 on CHD and CHD with various complications.
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Article
Evaluation of a new frequency–volume chart for children with primary monosymptomatic nocturnal enuresis: a prospective, comparative study
To improve compliance with voiding diaries in children with primary monosymptomatic nocturnal enuresis (PMNE), a new modified 3-day weekend frequency–volume chart (FVC) was designed, and the compliance and val...
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Article
Open AccessCorrection to: Effect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial
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Article
Open AccessThe association between plasma furin and cardiovascular events after acute myocardial infarction
Furin is the key enzyme involved in the cleavage of pro-BNP and plays a critical role in the cardiovascular system through its involvement in lipid metabolism, blood pressure regulation and the formation of at...
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Open AccessRetraction Note: Preoperative versus postoperative ultrasound-guided rectus sheath block for improving pain, sleep quality and cytokine levels in patients with open midline incisions undergoing transabdominal gynecological surgery: a randomized controlled trial
This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12871-021-01437-z
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Article
Open AccessUrinary levels of dimethoate, bisphenol A and benzo[a]pyrene in first-year students of Hohai University from different geographical regions
The objective of this study was to detect the urinary levels of dimethoate, benzo(a) pyrene (BaP), and bisphenol A (BPA) in first-year Hohai University students with different geographic origins.
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Article
Open AccessDetection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial
It’s a challenge for detecting the therapeutic targets of a polypharmacological drug from variations in the responsed networks in the differentiated populations with complex diseases, as stable coronary heart ...
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Article
Open AccessPro-inflammatory microenvironment and systemic accumulation of CXCR3+ cell exacerbate lung pathology of old rhesus macaques infected with SARS-CoV-2
Understanding the pathological features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in an animal model is crucial for the treatment of coronavirus disease 2019 (COVID-19). Here, w...
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Article
Open AccessEffect of Lycium barbarum polysaccharide supplementation in non-alcoholic fatty liver disease patients: study protocol for a randomized controlled trial
Non-alcohol fatty liver disease (NAFLD) is the most common chronic liver disease in the world, with a high incidence and no effective treatment. At present, the targeted therapy of intestinal microbes for NAFL...
