14,198 Result(s)
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Open AccessSafety of embryo cryopreservation: insights from mid-term placental transcriptional changes
In recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the application of embryo cryopreservation has been growing rapidly worldwide....
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Open AccessexpHRD: an individualized, transcriptome-based prediction model for homologous recombination deficiency assessment in cancer
Homologous recombination deficiency (HRD) stands as a clinical indicator for discerning responsive outcomes to platinum-based chemotherapy and poly ADP-ribose polymerase (PARP) inhibitors. One of the conventio...
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Open AccessHarnessing virus flexibility to selectively capture and profile rare circulating target cells for precise cancer subty**
The effective isolation of rare target cells, such as circulating tumor cells, from whole blood is still challenging due to the lack of a capturing surface with strong target-binding affinity and non-target-ce...
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Construction of iron oxyhydroxide/nickel sulfate hydroxide hybrid electrocatalyst for efficient oxygen evolution
Transition metal (TM) basic salts have been recognized as high-efficiency catalysts for electrocatalytic oxygen evolution reaction (OER), which is of great importance for producing clean hydrogen energy. Herei...
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Open AccessTannic acid coating gauze immobilized with thrombin with ultra-high coagulation activity and antimicrobial property for uncontrollable hemorrhage
Rapid and safe hemostasis is crucial for the survival of bleeding patients in prehospital care. It is urgent to develop high performance hemostatic material to control the massive hemorrhage in the military fi...
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Exosome theranostics: Comparative analysis of P body and exosome proteins and their mutations for clinical applications
Exosomes are lipid-bilayered vesicles, originating from early endosomes that capture cellular proteins and genetic materials to form multi-vesicular bodies. These exosomes are secreted into extracellular fluid...
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Open AccessAn adult with hemorrhagic varicella co-infects with cytomegalovirus: a case report
Hemorrhagic varicella (HV) is a particular form of chicken pox.,with high mortality in adults. This form of the disease is rare, to date, approximately 4 cases have been reported. Occasional cases of HV have b...
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Revealing the interplay of cognitive, meta-cognitive, and social processes in university students’ collaborative problem solving: a three-stage analytical framework
An in-depth analysis of collaborative problem solving (CPS) patterns contributes to understand team dynamics and effective paths to conflict resolution. However, there remains the lack of a perspective in the ...
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BL03HB: a Laue microdiffraction beamline for both protein crystallography and materials science at SSRF
A Laue microdiffraction beamline (BL03HB) was constructed at the Shanghai Synchrotron Radiation Facility (SSRF). This beamline features two consecutive focusing points in two different sectors within its end s...
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Open AccessImpact of perioperative COVID-19 infection on postoperative complication in cesarean section using Korean National Health insurance data
The vulnerability during pregnancy has raised concerns about the potential impact of COVID-19 on obstetric anesthesia, an essential aspect of maternal care during cesarean section procedures. To evaluate the i...
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Open AccessSynthetic macrolides overcoming MLSBK-resistant pathogens
Conventional macrolide-lincosamide-streptogramin B-ketolide (MLSBK) antibiotics are unable to counter the growing challenge of antibiotic resistance that is conferred by the constitutive methylation of rRNA base ...
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Open AccessStudy of baryon number transport dynamics and strangeness conservation effects using \(\Omega\) -hadron correlations
In nuclear collisions at RHIC energies, an excess of \(\Omega\) Ω hyperons ...
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Constructing three-dimensional hydrogen-bonding network and porous film from chitosan enables high-performance silicon@carbon anode
Anodes based on silicon@carbon (Si@C) composites are expected to be used in the next generation of commercial lithium-ion batteries due to their high specific capacity and high element abundance. However, part...
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Open AccessEpidemiological trends of subarachnoid hemorrhage at global, regional, and national level: a trend analysis study from 1990 to 2021
Subarachnoid hemorrhage (SAH) is a subtype of hemorrhagic stroke characterized by high mortality and low rates of full recovery. This study aimed to investigate the epidemiological characteristics of SAH betwe...
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Establishment of a multi-line immunochromatography based on magnetic nanoparticles for simultaneous screening of multiple biomarkers
Biomarkers screening is a benefit approach for early diagnosis of major diseases. In this study, magnetic nanoparticles (MNPs) have been utilized as labels to establish a multi-line immunochromatography (MNP-M...
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Fixed temperature polymerization during intermediate stage to synthesize highly crystallized g-C3N4 for photocatalytic hydrogen production
Graphitic carbon nitride (g-C3N4), owing to its unique structure, has emerged as a hotspot in the semiconductor photocatalytic hydrogen production. However, the intrinsic poor crystallinity of g-C3N4, which leads...
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Antiferromagnetic phase transition in a 3D fermionic Hubbard model
The fermionic Hubbard model (FHM)1 describes a wide range of physical phenomena resulting from strong electron–electron correlations, including conjectured mechanisms for unconventional superconductivity. Resolvi...
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A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and pathogenicity. Given the emergence of increasingly drug-resistant str...
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Open AccessApplication of data-driven blended online-offline teaching in medicinal chemistry for pharmacy students: a randomized comparison
The purpose of this study was to evaluate the effectiveness and efficiency of implementing a data-driven blended online-offline (DDBOO) teaching approach in the medicinal chemistry course.
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Open AccessInvestigation of the Circular Transcriptome in Alzheimer’s Disease Brain
Circular RNAs (circRNAs) are a subclass of non-coding RNAs which have demonstrated potential as biomarkers for Alzheimer’s disease (AD). In this study, we conducted a comprehensive exploration of the circRNA t...
