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23,235 Result(s)
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End of an era as GOP sweeps Hill
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The Limits of Medicine
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Too many scientists, too few academic jobs
Graduate education in the sciences is not doing its job. By preparing students only for academic research, the system neglects the range of opportunities for work in science that young scientists want and soci...
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Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease
The clinical use of fetal neural grafts as an intracerebral source of dopamine for patients with Parkinson's disease has met with limited success. Since basic fibroblast growth factor (bFGF) enhances the survi...
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Haemophiliacs seek compensation
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An opportunity in organ transplantation
Further progress in organ transplantation must overcome two key problems: a shortage of organs and long term immunological tolerance. Xenografts and immunological conditioning may help
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Many roads lead to atheroma
For many years cholesterol was seen as the worst enemy of coronary arteries. Recent advances show that interactions between lipoproteins, coagulation and growth factors are important in atherosclerosis.
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A question of culture
The demonstration, by Rutkowski et al. (page 80), that human Schwann cells can now be expanded to around 1 × 108 cells, provides a new opportunity for the study and therapy of myelin disorders.
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HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women
A crucial requirement in the rational design of a prophylactic vaccine against the hu-uman immunodeficiency virus (HIV) is to establish whether or not protective immunity can occur following natural infection....
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Hypersensitivity to nonsteroidal anti-inflammatory drugs
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Microsatellite instability in primary neoplasms from HIV+ patients
AIDS is associated with a high risk of certain malignancies, notably Kaposi's sarcoma (KS) and B-cell non-Hodgkin's lymphoma (NHL). The pathogenesis of these malignancies is not fully understood. One mechanism...
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Immunophilins and nervous system
The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cel...
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Serial magnetic resonance imaging of experimental atherosclerosis detects lesion fine structure, progression and complications in vivo
A major problem in the study of lesions of atherosclerosis is the difficulty of imaging noninvasively the lesions and following their progression in vivo. To address this problem, we have developed advanced magne...
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Returning Chinese power the ‘NIH’ of Taiwan
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European molecular medicine school opens its doors
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Molecular medicine in a changing world
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Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease
Ciliary neurotrophic factor (CNTF) rescues motor neurons in animal models of injury and neurodegeneration, and disruption of the mouse CNTF gene results in motor neuron degeneration in mature adults. Glial cel...
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DNA database to track nuclear plant effects
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Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury
Deposition of amyloid β-protein (Aβ) in the brain plays a key role in the pathogenesis of Alzheimer's disease. Apolipoprotein E ε4 allele (apo E-ε4) is a strong risk factor for Alzheimer's disease, and there is i...
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Raising the Dead, How We Die, Easing the Passage and Taking Charge