13,230 Result(s)

Article

End of an era as GOP sweeps Hill

Colin Macilwain in Nature Medicine (1995)

Article

The Limits of Medicine

Richard Jennings in Nature Medicine (1995)

Article

Basic fibroblast growth factor increases dopaminergic graft survival and function in a rat model of Parkinson's disease

The clinical use of fetal neural grafts as an intracerebral source of dopamine for patients with Parkinson's disease has met with limited success. Since basic fibroblast growth factor (bFGF) enhances the survi...

Hldeichi Takayama, Jasodhara Ray, Heather K. Raymon, Andrew Baird… in Nature Medicine (1995)

Article

An opportunity in organ transplantation

Further progress in organ transplantation must overcome two key problems: a shortage of organs and long term immunological tolerance. Xenografts and immunological conditioning may help

R. Y. Calne in Nature Medicine (1995)

Article

Many roads lead to atheroma

For many years cholesterol was seen as the worst enemy of coronary arteries. Recent advances show that interactions between lipoproteins, coagulation and growth factors are important in atherosclerosis.

Michael R. Hayden, Michael Reidy in Nature Medicine (1995)

Article

A question of culture

The demonstration, by Rutkowski et al. (page 80), that human Schwann cells can now be expanded to around 1 × 10⁸ cells, provides a new opportunity for the study and therapy of myelin disorders.

Hugo W. Moser in Nature Medicine (1995)

Article

Hypersensitivity to nonsteroidal anti-inflammatory drugs

Parnian Zia-Amirhosseini, Robert Z. Harris, Frances M. Brodsky… in Nature Medicine (1995)

Article

Microsatellite instability in primary neoplasms from HIV+ patients

AIDS is associated with a high risk of certain malignancies, notably Kaposi's sarcoma (KS) and B-cell non-Hodgkin's lymphoma (NHL). The pathogenesis of these malignancies is not fully understood. One mechanism...

Gauri C. Bedi, William H. Westra, Homayoon Farzadegan, Paula M. Pitha… in Nature Medicine (1995)

Article

Immunophilins and nervous system

The search for immunosuppressant drugs to increase the success of organ transplantation led to the discovery of the immunophilins, proteins that interface with a range of signal transduction systems inside cel...

Solomon H. Snyder, David M. Sabatini in Nature Medicine (1995)

Article

Serial magnetic resonance imaging of experimental atherosclerosis detects lesion fine structure, progression and complications in vivo

A major problem in the study of lesions of atherosclerosis is the difficulty of imaging noninvasively the lesions and following their progression in vivo. To address this problem, we have developed advanced magne...

Michael P. Skinner, Chun Yuan, Lee Mitsumori, Cecil E. Hayes… in Nature Medicine (1995)

Article

Regional changes of ciliary neurotrophic factor and nerve growth factor levels in post mortem spinal cord and cerebral cortex from patients with motor disease

Ciliary neurotrophic factor (CNTF) rescues motor neurons in animal models of injury and neurodegeneration, and disruption of the mouse CNTF gene results in motor neuron degeneration in mature adults. Glial cel...

P. Anand, A. Parrett, J. Martin, S. Zeman, P. Foley, M. Swash… in Nature Medicine (1995)

Article

Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury

Deposition of amyloid β-protein (Aβ) in the brain plays a key role in the pathogenesis of Alzheimer's disease. Apolipoprotein E ε4 allele (apo E-ε4) is a strong risk factor for Alzheimer's disease, and there is i...

James A.R. Nicoll, Gareth W. Roberts, David I. Graham in Nature Medicine (1995)

Article

Raising the Dead, How We Die, Easing the Passage and Taking Charge

James S. Ferguson Jr in Nature Medicine (1995)