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  1. Article

    Open Access

    Inhibiting YAP expression suppresses pancreatic cancer progression by disrupting tumor-stromal interactions

    Hippo/YAP pathway is known to be important for development, growth and organogenesis, and dysregulation of this pathway leads to tumor progression. We and others find that YAP is up-regulated in pancreatic duc...

    Zhengdong Jiang, Cancan Zhou, Liang Cheng in Journal of Experimental & Clinical Cancer … (2018)

  2. No Access

    Article

    Linear ubiquitin chain induces apoptosis and inhibits tumor growth

    Ubiquitination of proliferating cell nuclear antigen (PCNA) plays an important role in DNA damage response. Ectopic expression of PCNA fused at either terminus with ubiquitin (Ub) lacking two C-terminal glycin...

    Zhoushuai Qin, Wandong Jiang, Guifen Wang, Ying Sun, Wei **ao in Apoptosis (2018)

  3. Article

    Open Access

    Lipoxin A4 reverses mesenchymal phenotypes to attenuate invasion and metastasis via the inhibition of autocrine TGF-β1 signaling in pancreatic cancer

    Pancreatic cancer is a lethal disease in part because of its potential for aggressive invasion and metastasis. Lipoxin A4 (LXA4) is one of the metabolites that is derived from arachidonic acid and that is cata...

    Liang Zong, Ke Chen, Zhengdong Jiang in Journal of Experimental & Clinical Cancer … (2017)

  4. Article

    Open Access

    Addition of T2-guided optical tomography improves noncontrast breast magnetic resonance imaging diagnosis

    While dynamic contrast-enhanced magnetic resonance imaging (DCE MRI) is recognized as the most sensitive examination for breast cancer detection, it has a substantial false positive rate and gadolinium (Gd) co...

    **chao Feng, Junqing Xu, Shudong Jiang, Hong Yin, Yan Zhao in Breast Cancer Research (2017)

  5. Article

    Open Access

    Metformin suppresses cancer initiation and progression in genetic mouse models of pancreatic cancer

    Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-associated mortality worldwide with an overall five-year survival rate less than 7%. Accumulating evidence has revealed the cancer ...

    Ke Chen, Weikun Qian, Zhengdong Jiang, Liang Cheng, Jie Li in Molecular Cancer (2017)

  6. No Access

    Article

    Role of NRP-1 in VEGF-VEGFR2-Independent Tumorigenesis

    Recent studies suggest that neuropilin-1 (NRP-1) promotes angiogenesis mainly via VEGF and its receptors. It promotes tumorigenesis via formation of the NRP-1/ VEGF (vascular endothelial growth factor)/VEGFR2 ...

    Chenxi Hu, **aodong Jiang in Targeted Oncology (2016)

  7. No Access

    Article

    The role of B7-H1 in gastric carcinoma: clinical significance and related mechanism

    The aim of this study was to investigate the role of co-stimulatory molecule B7-H1 in gastric carcinoma, to assess its clinical significance, and to explore related mechanism. Expression of B7-H1 and interfero...

    Dong Jiang, Yun-yun Xu, Fang Li, Biao Xu, Xue-guang Zhang in Medical Oncology (2014)

  8. No Access

    Article

    Low expression of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin in non-Hodgkin lymphoma and a significant correlation with β2-microglobulin

    Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN), a member of the C-type lectin superfamily, has been reported to bind to various pathogens and several tumor cells and t...

    Dongbing Ding, Wenbin Chen, Changfu Zhang, Zhe Chen, Yanmei Jiang in Medical Oncology (2014)

  9. No Access

    Article

    Shorter Dinner-to-Bed Time is Associated with Gastric Cardia Adenocarcinoma Risk Partly in a Reflux-Dependent Manner

    Gastric cancer remains the second cause of cancer-related death worldwide. The aim of this study was to investigate the effects of shorter dinner-to-bed time, post-dinner walk, and obesity on gastric cardia ad...

    Qingxu Song MM, Jianbo Wang MD, Yibin Jia MD, Chuan Wang MD in Annals of Surgical Oncology (2014)

  10. Article

    Open Access

    Expression of cancer testis antigens and its correlation with clinicopathological parameters in hepatocellular carcinoma

    Meng Wang, **n-feng Chen, Zhi-qin Li, Zhen Zhang in Journal for ImmunoTherapy of Cancer (2013)

  11. No Access

    Article

    Identification of novel serological tumor markers for human prostate cancer using integrative transcriptome and proteome analysis

    The aim of this study was to identify novel serological tumor markers for human prostate cancer (PCa). We compared the gene expression profile of PCa tissues to adjacent benign tissues of prostate using gene e...

    Zhao-dong Han, Yan-qiong Zhang, Hui-chan He, Qi-shan Dai, Guo-qiang Qin in Medical Oncology (2012)

  12. No Access

    Article

    Clinical study on the recombinant human endostatin regarding improving the blood perfusion and hypoxia of non-small-cell lung cancer

    To observe the dynamic changes of blood perfusion and hypoxic status with CT perfusion imaging and hypoxia imaging in patients of non-small-cell lung cancer (NSCLC) who were treated with recombinant human endo...

    **ao-Dong Jiang, Peng Dai, Yun Qiao, ** Wu in Clinical and Translational Oncology (2012)

  13. No Access

    Article

    Preliminary clinical study of weekly recombinant human endostatin as a hypoxic tumour cell radiosensitiser combined with radiotherapy in the treatment of NSCLC

    To investigate the clinical effects and adverse effects of weekly recombinant human endostatin (RHES) as a hypoxic tumour cell radiosensitiser combined with radiotherapy in the treatment of non-small-cell lung...

    **ao-Dong Jiang, Yun Qiao, Peng Dai, ** Wu in Clinical and Translational Oncology (2012)

  14. No Access

    Article

    Variation in Cadmium Tolerance and Accumulation and Their Relationship in Wheat Recombinant Inbred Lines at Seedling Stage

    In order to identify the variation of cadmium (Cd) tolerance and accumulation in wheat (Triticum aestivum L.), a study was conducted in hydroponic culture with or without Cd using recombinant inbred lines (RILs) ...

    Dunwei Ci, Dong Jiang, Tingbo Dai, Qi **g in Biological Trace Element Research (2011)

  15. No Access

    Article

    Risk of genome-wide association study newly identified genetic variants for breast cancer in Chinese women of Heilongjiang Province

    Recent genome-wide association studies have identified seven single nucleotide polymorphisms (SNPs) associated with breast cancer, but mainly in Europeans. In this study, the authors evaluated the effect of th...

    Yongdong Jiang, Jiguang Han, **g Liu in Breast Cancer Research and Treatment (2011)

  16. No Access

    Article

    Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer

    Runx3 and CHFR genes were defined as tumor suppressor genes in gastric cancer (GC) recently. This paper was to investigate the roles of methylation and expression status of Runx3 and CHFR genes in GC patients....

    Shi-Lian Hu, Da-Bing Huang, Yu-Bei Sun, Lei Wu, Wei-** Xu, Shi Yin in Medical Oncology (2011)

  17. No Access

    Article

    Application of proton MR spectroscopy on evaluation of radiotherapy treated intracranial tumors

    To evaluate the clinical application of proton magnetic resonance spectroscopy (1HMRS) in patients with radiotherapy treated intracranial tumors.

    **aodong Jiang, Liangyu Shi, Da’an Song in The Chinese-German Journal of Clinical Onc… (2007)

  18. No Access

    Article

    Clinical study on concurrent and sequential therapy of intensity modulated radiation therapy (IMRT) combined with NP regimen chemotherapy in the treatment of middle and advanced non-small cell lung cancer

    To evaluate the clinical effects of concurrent and sequential therapy for middle and advanced stage non-small cell lung cancer (NSCLC) useing IMRT combined with NP regimen chemotherapy.

    **aodong Jiang, Da’an Song, Weiming Zhang in The Chinese-German Journal of Clinical Onc… (2007)

  19. No Access

    Article

    Synuclein Gamma Inhibits the Mitotic Checkpoint Function and Promotes Chromosomal Instability of Breast Cancer Cells

    Aberrant expressions of the neuronal protein synuclein gamma (SNCG) in malignant mammary epithelial cells are strongly associated with the progression of breast cancer. SNCG is not expressed in normal breast t...

    Satoru Inaba, Cong Li, Y. Eric Shi, Dan-Qing Song in Breast Cancer Research and Treatment (2005)

  20. No Access

    Article

    The basis of T-cell-mediated immunity to chronic myelogenous leukemia

    Jeffrey J Molldrem, Shreya Kant, Weidong Jiang, Sijie Lu in Oncogene (2002)

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