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Open AccessChondrogenic Potential of Peripheral Blood Derived Mesenchymal Stem Cells Seeded on Demineralized Cancellous Bone Scaffolds
As a cell source with large quantity and easy access, peripheral blood mesenchymal stem cells (PBMSCs) were isolated and seeded in porcine demineralized cancellous bone (DCB) scaffolds, cultured in chondrogeni...
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Article
Open AccessPhotoelectrochemical detection of alpha-fetoprotein based on ZnO inverse opals structure electrodes modified by Ag2S nanoparticles
In this work, a new photoelectrochemical biosensor based on Ag2S nanoparticles (NPs) modified macroporous ZnO inverse opals structure (IOs) was developed for sensitive and rapid detection of alpha fetal protein (...
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Article
Open AccessClinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
To investigate the prognostic values of clinical factors 72 h within traumatic cervical spinal cord injury (TCSCI). Data were extracted from the medical materials of 57 TCSCI cases. AIS was used as the outcome...
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Article
Open AccessChlorogenic acid inhibits glioblastoma growth through repolarizating macrophage from M2 to M1 phenotype
Glioblastoma is an aggressive tumor that is associated with distinctive infiltrating microglia/macrophages populations. Previous studies demonstrated that chlorogenic acid (5-caffeoylquinic acid, CHA), a pheno...
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Article
Open AccessPolydatin protects the respiratory system from PM2.5 exposure
Atmospheric particle is one of the risk factors for respiratory disease; however, their injury mechanisms are poorly understood, and prevention methods are highly desirable. We constructed artificial PM2.5 (aPM2....
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Article
Open AccessCorrection: Corrigendum: Vesicle Size Regulates Nanotube Formation in the Cell
Scientific Reports 6: Article number: 24002; published online: 07 April 2016; updated: 09 February 2017 He Ren and Chuanmao Zhang were omitted from the author list in the original version of this Article. This...
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Open AccessSelection for Oil Content During Soybean Domestication Revealed by X-Ray Tomography of Ancient Beans
When and under what circumstances domestication related traits evolved in soybean (Glycine max) is not well understood. Seed size has been a focus of archaeological attention because increased soybean seed weight...
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Article
Open AccessDeterministic secure quantum communication using a single d-level system
Deterministic secure quantum communication (DSQC) can transmit secret messages between two parties without first generating a shared secret key. Compared with quantum key distribution (QKD), DSQC avoids the wa...
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Article
Open AccessThe influence of environmental factors on communities of arbuscular mycorrhizal fungi associated with Chenopodium ambrosioides revealed by MiSeq sequencing investigation
Arbuscular mycorrhizal fungi (AMF) affect multiple ecosystem functions and processes, the assemblages of which vary across ecosystems. However, the influences of environmental factors on AMF communities which ...
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Article
Open AccessFarnesoid X receptor, a novel proto-oncogene in non-small cell lung cancer, promotes tumor growth via directly transactivating CCND1
Farnesoid X receptor (FXR), a nuclear receptor for maintaining bile acid homeostasis, has been recognized as a tumor suppressor in enterohepatic tissues. However, its expression and functional role in non-smal...
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Article
Open AccessDual Roles of Two Isoforms of Autophagy-related Gene ATG10 in HCV-Subgenomic replicon Mediated Autophagy Flux and Innate Immunity
Autophagy and immune response are two defense systems that human-body uses against viral infection. Previous studies documented that some viral mechanisms circumvented host immunity mechanisms and hijacked aut...
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Open AccessNon-destructive evaluation of UV pulse laser-induced damage performance of fused silica optics
The surface laser damage performance of fused silica optics is related to the distribution of surface defects. In this study, we used chemical etching assisted by ultrasound and magnetorheological finishing to...
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Open AccessCorrection: Corrigendum: Soil warming enhances the hidden shift of elemental stoichiometry by elevated CO2 in wheat
Scientific Reports 6: Article number: 23313; published online: 22 March 2016; updated: 22 December 2017. The authors neglected to cite two previous studies related to the effect of elevated CO2 on minerals. Th...
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Open AccessIndividuals with depressive tendencies experience difficulty in forgetting negative material: two mechanisms revealed by ERP data in the directed forgetting paradigm
Although previous studies have shown that individuals with depressive tendencies have deficits in forgetting negative material, the detailed underlying neural mechanisms have not been elucidated. This study ex...
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Open AccessPhysiological and biochemical changes during drought and recovery periods at tillering and jointing stages in wheat (Triticum aestivum L.)
Defining the metabolic strategies used by wheat to tolerate and recover from drought events will be important for ensuring yield stability in the future, but studies addressing this critical research topic are...
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Article
Open AccessMolecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines
Lomaiviticin A and difluostatin A are benzofluorene-containing aromatic polyketides in the atypical angucycline family. Although these dimeric compounds are potent antitumor agents, how nature constructs their...
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Article
Open AccessSingle-shot 3D coherent diffractive imaging of core-shell nanoparticles with elemental specificity
We report 3D coherent diffractive imaging (CDI) of Au/Pd core-shell nanoparticles with 6.1 nm spatial resolution with elemental specificity. We measured single-shot diffraction patterns of the nanoparticles us...
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Open AccessThe Radiated Deep-frozen Xenogenic Meniscal Tissue Regenerated the Total Meniscus with Chondroprotection
Meniscal allograft transplantation yields good and excellent results but is limited by donor availability. The purpose of the study was to evaluate the effectiveness of radiated deep-frozen xenogenic meniscal ...
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Article
Open AccessMap** the Potential Global Codling Moth (Cydia pomonella L.) Distribution Based on a Machine Learning Method
The spread of invasive species may pose great threats to the economy and ecology of a region. The codling moth (Cydia pomonella L.) is one of the 100 worst invasive alien species in the world and is the most dest...
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Open AccessIMB-T130 targets 3-dehydroquinate synthase and inhibits Mycobacterium tuberculosis
The anti-tuberculosis (TB) agent IMB-T130 was speculated to be a multi-target compound. In this research, we found that IMB-T130 inhibits the catalytic activity of Mycobacterium tuberculosis 3-dehydroquinate synt...