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Article
Open AccessOral arsenic plus imatinib versus imatinib solely for newly diagnosed chronic myeloid leukemia: a randomized phase 3 trial with 5-year outcomes
The synergistic effects of combining arsenic compounds with imatinib against chronic myeloid leukemia (CML) have been established using in vitro data. We conducted a clinical trial to compare the efficacy of t...
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Article
Naoxueshu Oral Liquid Accelerates Post-Craniotomy Hematoma Absorption in Patients: An Open-Label, Multicenter, and Randomized Controlled Trial
To investigate whether Naoxueshu Oral Liquid (NXS) could promote hematoma absorption in post-craniotomy hematoma (PCH) patients.
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Article
Open AccessRenal interstitial fibrotic assessment using non-Gaussian diffusion kurtosis imaging in a rat model of hyperuricemia
To investigate the feasibility of Diffusion Kurtosis Imaging (DKI) in assessing renal interstitial fibrosis induced by hyperuricemia.
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Article
Resourceful preparation of Sb2O3 in hazardous As-Sb dust from typical lead smelter
Hazardous arsenic antimony dust (HAAD), a perilous by-product with significant antimony and arsenic concentrations generated in lead smelters, poses a substantial environmental threat. The imperative of resour...
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Article
Enhanced transport of K-nZVI by bentonite suspensions in porous media
Due to high reactivity and relatively low cost, nano zero-valent iron (nZVI) has become an alternative material for in-situ remediation of contaminated sites. However, factors such as short transport distance ...
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Article
Bioinspired design of integral molded Janus silk fibroin-MXene evaporator for efficient solar vapor generation
Solar vapor generation is a promising sustainable technology that uses solar distillation to produce fresh water from seawater and wastewater, hel** relieve global water resource shortage. Here, inspired by ...
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Article
The Diagnostic Value of Carnett’s Test with Chronic Abdominal Pain: A Narrative Review
Chronic abdominal wall pain is a poorly recognized cause of chronic abdominal pain, and patients frequently go misdiagnosed despite a battery of medical tests. The Carnett’s test is a diagnostic tool used to d...
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Article
AHA Life’s Essential 8 and new-onset CKD: a prospective cohort study from the UK Biobank
The AHA has recently introduced a novel metric, Life's Essential 8, to assess cardiovascular health (CVH). Nevertheless, the association between varying levels of LE8 and the propensity for CKD is still unclea...
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Article
Effect of blade tilt angle on fluid flow characteristics in spray-blowing agitation composite process: a simulation
Aiming at the paddle tilt angle of the spray-blowing agitation composite process, the four-blade stirring and blowing composite desulfurization agitator was chosen as the research object, and the computational...
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Article
Open AccessCorrection to: Assembly-level analysis on temperature coefficient of reactivity in a graphite-moderated fuel salt reactor fueled with low-enriched uranium
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Article
Effect and Safety of Herbal Medicine Foot Baths in Patients with Diabetic Peripheral Neuropathy: A Multicenter Double-Blind Randomized Controlled Trial
To evaluate the effect and safety of foot baths with Tangbi Waixi Decoction (TW) in treating patients with diabetic peripheral neuropathy (DPN).
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Article
Endothelial extracellular vesicles induce acute lung injury via follistatin-like protein 1
Cardiopulmonary bypass has been speculated to elicit systemic inflammation to initiate acute lung injury (ALI), including acute respiratory distress syndrome (ARDS), in patients after cardiac surgery. We previ...
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Article
The Alasu rock avalanche in the Tianshan Mountains, China: fragmentation, landforms, and kinematics
Geomorphological and sedimentological characteristics are key evidences for understanding the emplacement mechanisms of rock avalanches. Based on remote sensing, photogrammetry, and field surveys, the depositi...
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Article
Propagation form of internal cracks induced by continuous casting soft reduction and control strategy for internal quality
The propagation form of internal cracks induced by continuous casting soft reduction and the control strategy for enhancing the internal quality of 45 steel through industrial trials and a three-dimensional fl...
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Article
Open AccessThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...
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Article
Open AccessUltra-efficient MCF-7 cell ablation and chemotherapy-integrated electrothermal therapy with DOX–WS2–PEG–M13 nanostructures
Clinical trials have generated encouraging outcomes for the utility of thermal agents (TAs) in cancer thermal therapy (TT). Although the fast breakdown of TAs alleviates safety concerns, it restricts the therm...
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Article
Open AccessMicroRNA-377-3p exacerbates chronic obstructive pulmonary disease through suppressing ZFP36L1 expression and inducing lung fibroblast senescence
Chronic obstructive pulmonary disease (COPD) is a leading aging related cause of global mortality. Small airway narrowing is recognized as an early and significant factor for COPD development. Senescent fibrob...
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Article
Open AccessArtesunate treats obesity in male mice and non-human primates through GDF15/GFRAL signalling axis
Obesity, a global health challenge, is a major risk factor for multiple life-threatening diseases, including diabetes, fatty liver, and cancer. There is an ongoing need to identify safe and tolerable therapeut...
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Article
DLF-YOLOF: an improved YOLOF-based surface defect detection for steel plate
Surface defects can affect the quality of steel plate. Many methods based on computer vision are currently applied to surface defect detection of steel plate. However, their real-time performance and object de...
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Article
LncRNA LY6E-DT and its encoded metastatic-related protein play oncogenic roles via different pathways and promote breast cancer progression
Abnormal long noncoding RNA (lncRNA) expression plays an important role in tumor invasion and metastasis. Here, we show that lncRNA LY6E divergent transcript (LY6E-DT) levels are increased in breast cancer (BC...
