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Article
Open AccessSmooth muscle 22 alpha protein inhibits VSMC foam cell formation by supporting normal LXRα signaling, ameliorating atherosclerosis
Vascular smooth muscle cells (VSMCs) are indispensable components in foam cell formation in atherosclerosis. However, the mechanism behind foam cell formation of VSMCs has not been addressed. We found a potent...
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Article
High nitrogen uptake and utilization contribute to the dominance of invasive Spartina alterniflora over native Phragmites australis
A field experiment was conducted to investigate nitrogen (N)-form uptake preference and N utilization efficiency of an invasive plant Spartina alterniflora and its co-occurring native plant Phragmites australis i...
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Article
The deubiquitinase USP25 supports colonic inflammation and bacterial infection and promotes colorectal cancer
Bacterial infection or abnormal colonization in the gastrointestinal system is associated with subsets of inflammatory bowel disease and colorectal cancer. Here we demonstrated essential roles of ubiquitin-spe...
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Article
Open AccessAgrobacterium-mediated genetic transformation of Chinese chestnut (Castanea mollissima Blume)
Chinese chestnut (Castanea mollissima) is an important germplasm resource for the breeding of Castanea species worldwide with vital ecological and economic value. Biotechnology overcomes the limitations of tradit...
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Article
5-methylcytosine promotes pathogenesis of bladder cancer through stabilizing mRNAs
Although 5-methylcytosine (m5C) is a widespread modification in RNAs, its regulation and biological role in pathological conditions (such as cancer) remain unknown. Here, we provide the single-nucleotide resoluti...
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Article
Open AccessIdentification and characterization of GmMYB118 responses to drought and salt stress
Abiotic stress severely influences plant growth and development. MYB transcription factors (TFs), which compose one of the largest TF families, play an important role in abiotic stress responses.
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Article
Open AccessMolecular genetic and biochemical evidence for adaptive evolution of leaf abaxial epicuticular wax crystals in the genus Lithocarpus (Fagaceae)
Leaf epicuticular wax is an important functional trait for physiological regulation and pathogen defense. This study tests how selective pressure may have forced the trait of leaf abaxial epicuticular wax crys...
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Article
Microsatellite records for volume 10, issue 3
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Article
Open AccessLong non-coding RNA GAS5 suppresses pancreatic cancer metastasis through modulating miR-32-5p/PTEN axis
Long non-coding RNA growth arrest-specific transcript 5 (lncRNA GAS5) is a well-known tumor suppressor in the pathogenesis of a variety of human cancers. The precise role of GAS5 in pancreatic cancer (PC) prog...
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Article
Effect of salt treatment on growth, isoenzymes and metabolites of Andrographis paniculata (Burm. f.) Nees
Andrographis paniculata is a well-known medicinal plant having vast therapeutic potentials. Efficient use of saline land for promoting the cultivation of medicinal plants is valuable for pharmace...
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Article
Open AccessGenome analysis and signature discovery for diving and sensory properties of the endangered Chinese alligator
Crocodilians are diving reptiles that can hold their breath under water for long periods of time and are crepuscular animals with excellent sensory abilities. They comprise a sister lineage of birds and have n...
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Article
PJS, a novel isocoumarin with hexahydropyrimidine ring from Bacillus subtilis PJS
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Open AccessBMSCs reduce rat granulosa cell apoptosis induced by cisplatin and perimenopause
The objective of this study was to evaluate the effect of bone marrow mesenchymal stem cells (BMSCs) on the apoptosis of granulosa cells (GCs) in rats.
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Chapter
Recombinant Allergens and Applications
Recombinant DNA technology has great potential in various aspects of allergen-related research and clinical applications. Sufficient amounts of purified wild-type or immunologically modified allergens or fragm...
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Chapter
Overview of Allergen Sources in China
China is a large country both in area and population size, with diverse landscapes, climates and environments, and its domestic economy, international trade and tourism is rapidly growing. Under such condition...
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Chapter
Fruit Allergy and Genetic and Genomic Tools to Select Hypoallergenic Fruit Cultivars
Fruit allergy has become a health problem with regard to food safety and quality of life. Breeding and selection of hypoallergenic fruit cultivars is an efficient way to counteract allergy. This chapter review...