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    Article

    Divergent clonal selection dominates medulloblastoma at recurrence

    The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon–driven, functional ...

    A. Sorana Morrissy, Livia Garzia, David J. H. Shih, Scott Zuyderduyn, ** Huang in Nature (2016)

  2. Article

    Open Access

    Stimulation of autophagy promotes functional recovery in diabetic rats with spinal cord injury

    In this study we examined the relationship between autophagy and apoptosis in diabetic rats after spinal cord injury (SCI), also we determined the role of autophagy in diabetes-aggravated neurological injury in v...

    Kai-liang Zhou, Yi-fei Zhou, Kai Wu, Nai-feng Tian, Yao-sen Wu in Scientific Reports (2015)

  3. Article

    Open Access

    Crude oil as a microbial seed bank with unexpected functional potentials

    It was widely believed that oil is a harsh habitat for microbes because of its high toxicity and hydrophobicity. However, accumulating evidence has revealed the presence of live microbes in crude oil. Therefor...

    Man Cai, Yong Nie, Chang-Qiao Chi, Yue-Qin Tang, Yan Li in Scientific Reports (2015)

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    Article

    Skp2–MacroH2A1–CDK8 axis orchestrates G2/M transition and tumorigenesis

    Understanding the mechanism by which cell growth, migration, polyploidy, and tumorigenesis are regulated may provide important therapeutic strategies for cancer therapy. Here we identify the Skp2–macroH2A1 (mH...

    Dazhi Xu, Chien-Feng Li, **an Zhang, Zhaohui Gong, Chia-Hsin Chan in Nature Communications (2015)

  5. Article

    Open Access

    The Relationship between Dietary Protein Consumption and Risk of Fracture: a subgroup and dose-response meta-analysis of prospective cohort studies

    It is still debate of the relationship between the dietary protein consumption and risk of fracture. We searched Medline and Embase to assess the effects of dietary protein consumption on risk of fracture. Twe...

    Ai-Min Wu, **ao-Lei Sun, Qing-Bo Lv, Yong Zhou, Dong-Dong **a in Scientific Reports (2015)

  6. Article

    Open Access

    Dissecting the Mechanism of Martensitic Transformation via Atomic-Scale Observations

    Martensitic transformation plays a pivotal role in the microstructural evolution and plasticity of many engineering materials. However, so far the underlying atomic processes that accomplish the displacive tra...

    Xu-Sheng Yang, Sheng Sun, **ao-Lei Wu, Evan Ma, Tong-Yi Zhang in Scientific Reports (2014)

  7. Article

    Open Access

    Diverse alkane hydroxylase genes in microorganisms and environments

    AlkB and CYP153 are important alkane hydroxylases responsible for aerobic alkane degradation in bioremediation of oil-polluted environments and microbial enhanced oil recovery. Since their distribution in natu...

    Yong Nie, Chang-Qiao Chi, Hui Fang, Jie-Liang Liang, She-Lian Lu in Scientific Reports (2014)

  8. Article

    Open Access

    Electrostatic Induced Stretch Growth of Homogeneous β-Ni(OH)2 on Graphene with Enhanced High-Rate Cycling for Supercapacitors

    Supercapacitors, as one of alternative energy devices, have been characterized by the rapid rate of charging and discharging and high power density. But they are now challenged to achieve their potential energ...

    Zhong Wu, **ao-Lei Huang, Zhong-Li Wang, Ji-**g Xu, Heng-Guo Wang in Scientific Reports (2014)

  9. No Access

    Article

    Growth of non-phototrophic microorganisms using solar energy through mineral photocatalysis

    Phototrophy and chemotrophy are two dominant modes of microbial metabolism. To date, non-phototrophic microorganisms have been excluded from the solar light-centered phototrophic metabolism. Here we report a p...

    Anhuai Lu, Yan Li, Song **, **n Wang, **ao-Lei Wu, Cui** Zeng in Nature Communications (2012)

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