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  1. Article

    Open Access

    Homocysteine is a bystander for ST-segment elevation myocardial infarction: a case-control study

    Homocysteine has been long considered a risk factor for atherosclerosis. However, cardiovascular events cannot be reduced through homocysteine lowering by B vitamin supplements. Although several association st...

    Ching-Yu Julius Chen, Tzu-Ching Yang, Christopher Chang in BMC Cardiovascular Disorders (2018)

  2. Article

    Open Access

    Identification of tick-borne pathogen diversity by metagenomic analysis in Haemaphysalis longicornis from **nyang, China

    A wide variety of pathogens could be maintained and transmitted by Haemaphysalis longicornis. The aim of this study is to systematically examine the variety of pathogens carried by Haemaphysalis longicornis, an i...

    Lu Zhuang, Juan Du, **ao-Ming Cui, Hao Li, Fang Tang in Infectious Diseases of Poverty (2018)

  3. Article

    Open Access

    Tuberculosis among migrant workers in Taiwan

    Although the worldwide incidence of tuberculosis (TB) has been slowly decreasing, the migrant workers remains an important gap for regional TB control. In Taiwan, the numbers of the migrant workers from countr...

    Chia-Wen Lu, Yi-Hsuan Lee, Yu-Hao Pan, Hao-Hsiang Chang in Globalization and Health (2019)

  4. Article

    Open Access

    The efficacy of limited endoscopic sphincterotomy plus endoscopic papillary large balloon dilation for removal of large bile duct stones

    The removal of large bile duct stones (> 15 mm) by conventional endoscopic sphincterotomy (EST) and endoscopic papillary balloon dilation (EPBD) can be challenging, requiring mechanical lithotripsy (ML) in add...

    Chung-Mou Kuo, Yi-Chun Chiu, Chih-Ming Liang, Cheng-Kun Wu in BMC Gastroenterology (2019)

  5. Article

    Open Access

    A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)

    In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020. For it is a ...

    Ying-Hui **, Lin Cai, Zhen-Shun Cheng, Hong Cheng, Tong Deng in Military Medical Research (2020)

  6. Article

    Open Access

    Chemoprophylaxis, diagnosis, treatments, and discharge management of COVID-19: An evidence-based clinical practice guideline (updated version)

    The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of a rapidly spreading illness, coronavirus disease 2019 (COVID-19), affecting more than seventeen million people around the ...

    Ying-Hui **, Qing-Yuan Zhan, Zhi-Yong Peng, Xue-Qun Ren in Military Medical Research (2020)

  7. Article

    Open Access

    Prediction of vaginal birth after cesarean delivery in Southeast China: a retrospective cohort study

    We aimed to develop and validate a nomogram for effective prediction of vaginal birth after cesarean (VBAC) and guide future clinical application.

    Hua-Le Zhang, Liang-Hui Zheng, Li-Chun Cheng, Zhao-Dong Liu in BMC Pregnancy and Childbirth (2020)

  8. Article

    Open Access

    Efficacy and Safety of Baricitinib in Chinese Rheumatoid Arthritis Patients and the Subgroup Analyses: Results from Study RA-BALANCE

    Baricitinib is an oral selective inhibitor of Janus kinase (JAK) 1 and JAK 2, which has demonstrated significant efficacy in patients with moderately to severely active rheumatoid arthritis (RA). This analysis...

    Yue Yang, **ng-Fu Li, **ao Zhang, Chun-De Bao, Jian-Kang Hu in Rheumatology and Therapy (2020)

  9. Article

    Open Access

    Dysphagia and masticatory performance as a mediator of the xerostomia to quality of life relation in the older population

    The impact of poor oral health on older adults’ quality of life is a public health problem. In this study, the mediating effects of dental status, occlusal condition, dysphagia, and masticatory performance on ...

    Ting-Yu Lu, Jen-Hao Chen, Je-Kang Du, Ying-Chun Lin, Pei-Shan Ho in BMC Geriatrics (2020)

  10. Article

    Open Access

    Mental health problems and social supports in the COVID-19 healthcare workers: a Chinese explanatory study

    Coronavirus disease 2019 (COVID-19) has spread rapidly in China and other overseas areas, which has aroused widespread concern. The sharp increase in the number of patients has led to great psychological press...

    Xue-Hui Fang, Li Wu, Lun-Shan Lu, **ao-Hong Kan, Hua Wang, Yan-Jun **ong in BMC Psychiatry (2021)

  11. Article

    Open Access

    Surgical resection significantly promotes the overall survival of patients with hepatocellular carcinoma: a propensity score matching analysis

    The benefits of surgical resection (SR) for various Barcelona Clinic Liver Cancer (BCLC) stages of hepatocellular carcinoma (HCC) remain unclear. We investigated the risk factors of overall survival (OS) and s...

    Yaw-Sen Chen, Pei-Min Hsieh, Hung-Yu Lin, Chao-Ming Hung, Gin-Ho Lo in BMC Gastroenterology (2021)

  12. Article

    Open Access

    Safety and efficacy of meplazumab in healthy volunteers and COVID-19 patients: a randomized phase 1 and an exploratory phase 2 trial

    Recent evidence suggests that CD147 serves as a novel receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Blocking CD147 via anti-CD147 antibody could suppress the in vitro SAR...

    Huijie Bian, Zhao-Hui Zheng, Ding Wei in Signal Transduction and Targeted Therapy (2021)

  13. Article

    Open Access

    Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and therapeutic interventions

    The coronavirus disease 2019 (COVID-19) pandemic has caused large-scale economic and social losses and worldwide deaths. Although most COVID-19 patients have initially complained of respiratory insufficiency, ...

    Ying Han, Kai Yuan, Zhe Wang, Wei-Jian Liu, Zheng-An Lu in Translational Psychiatry (2021)

  14. Article

    Open Access

    Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients

    Azvudine (FNC) is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase (RdRp). Recently, we discovered FNC an agent against SARS-CoV-2, and have taken it into Phase III trial for COVID-19 patie...

    **-Lan Zhang, Yu-Huan Li, Lu-Lu Wang in Signal Transduction and Targeted Therapy (2021)

  15. Article

    Open Access

    Diagnostic value of apparent diffusion coefficient in predicting pathological T stage in patients with thymic epithelial tumor

    This study aimed to evaluate the diagnostic capacity of apparent diffusion coefficient (ADC) in predicting pathological Masaoka and T stages in patients with thymic epithelial tumors (TETs).

    Chao-Chun Chang, Chia-Ying Lin, Li-Ting Huang, Ming-Tsung Chuang in Cancer Imaging (2022)

  16. Article

    Open Access

    Multimodal ultrasound features of breast cancers: correlation with molecular subtypes

    To investigate whether multimodal intratumour and peritumour ultrasound features correlate with specific breast cancer molecular subtypes.

    Jun-Yan Zhu, Han-Lu He, **ao-Chun Jiang, Hai-Wei Bao, Fen Chen in BMC Medical Imaging (2023)

  17. Article

    Open Access

    Machine learning combined with radiomics and deep learning features extracted from CT images: a novel AI model to distinguish benign from malignant ovarian tumors

    To develop an artificial intelligence (AI) model with radiomics and deep learning (DL) features extracted from CT images to distinguish benign from malignant ovarian tumors.

    Ya-Ting Jan, Pei-Shan Tsai, Wen-Hui Huang, Ling-Ying Chou in Insights into Imaging (2023)

  18. Article

    Open Access

    Efficacy of Qingpeng ointment (a Tibetan medicine) for acute gouty arthritis: a multi-center, randomized, double-blind, placebo-controlled trial

    This study aims to assess the efficacy and safety of Qingpeng ointment (QPO), a Tibetan medicine for alleviating symptoms in individuals with acute gouty arthritis (AGA).

    Ya-xi Shang, Shu-feng Wei, Ke-peng Yang in BMC Complementary Medicine and Therapies (2024)

  19. Article

    Open Access

    Relationship between shoulder and elbow range of motion and ultrasonographic structural abnormalities in the elbow of Taiwanese high school baseball players

    Ultrasonographic structural abnormalities are regarded as one of the risk factors of elbow injuries. Elbow injuries are commonly associated with decreased shoulder/elbow range of motion (ROM). The purpose of t...

    Yi Lu, Poyu Chen, Wen-Yi Chou in BMC Sports Science, Medicine and Rehabilit… (2024)

  20. Article

    Open Access

    Comparing transfusion reactions between pre-storage and post-storage leukoreduced apheresis platelets: an analysis using propensity score matching

    Transfusion reactions induced by platelet transfusions may be reduced and alleviated by leukocyte reduction of platelets. Although leukoreduction of apheresis platelets can be performed either pre-storage or p...

    Sheng-Hsuan Chien, Hsin-Yi Huang, Ying-Ju Chen, Yu-Chen Tsai in Annals of Hematology (2024)

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