601 Result(s)

Article

Fully semantic segmentation for rectal cancer based on post-nCRT MRl modality and deep learning framework

Rectal tumor segmentation on post neoadjuvant chemoradiotherapy (nCRT) magnetic resonance imaging (MRI) has great significance for tumor measurement, radiomics analysis, treatment planning, and operative strat...

Shaojun **a, Qingyang Li, Hai-Tao Zhu, **ao-Yan Zhang, Yan-Jie Shi, Ding Yang… in BMC Cancer (2024)

Article

ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia

In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly under...

Tao-Yan Lin, Jun-Shuang Jia, Wei-Ren Luo… in Journal of Experimental & Clinical Cancer … (2024)

Article

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins

Mixed-lineage leukemia (MLL) fusion gene caused by chromosomal rearrangement is a dominant oncogenic driver in leukemia. Due to having diverse MLL rearrangements and complex characteristics, MLL leukemia treated ...

Tian-Qi Chen, Heng-**g Huang, Shun-**n Zhu… in Experimental Hematology & Oncology (2024)

Article

RhoB expression associated with chemotherapy response and prognosis in colorectal cancer

To examine the role of RhoB expression in relation to chemotherapy response, clinical outcomes and associated signaling pathways in colorectal cancer patients.

Maria Kopsida, Na Liu, Angeliki Kotti, **g Wang, Lasse Jensen… in Cancer Cell International (2024)

Article

Research progress of Paris polyphylla in the treatment of digestive tract cancers

Cancer has become one of the most important causes of human death. In particular, the 5 year survival rate of patients with digestive tract cancer is low. Although chemotherapy drugs have a certain efficacy, t...

Jia Wang, Bao-yi Ni, **g Wang, Lei Han, **n Ni, **n-miao Wang… in Discover Oncology (2024)

Article

Author Correction: Perioperative toripalimab and chemotherapy in locally advanced gastric or gastro-esophageal junction cancer: a randomized phase 2 trial

Shu-Qiang Yuan, Run-Cong Nie, Ying **, Cheng-Cai Liang, Yuan-Fang Li… in Nature Medicine (2024)

Article

Differential patterns of reproductive and lifestyle risk factors for breast cancer according to birth cohorts among women in China, Japan and Korea

The birth cohort effect has been suggested to influence the rate of breast cancer incidence and the trends of associated reproductive and lifestyle factors. We conducted a cohort study to determine whether a d...

Salma Nabila, Ji-Yeob Choi, Sarah Krull Abe, Md Rashedul Islam… in Breast Cancer Research (2024)

Article

Retraction Note to: Alternol inhibits proliferation and induces apoptosis in mouse lymphocyte leukemia (L1210) cells

Zhao-Zhe Liu, ** Zhu, Bo Sun, Shu Liu, Shuo Geng… in Molecular and Cellular Biochemistry (2024)

Article

Gene delivery to breast cancer by incorporated EpCAM targeted DARPins into AAV2

The aim of this study is to evaluate an AAV vector that can selectively target breast cancer cells and to investigate its specificity and anti-tumor effects on breast cancer cells both in vitro and in vivo, of...

Ya-feng Lv, Hao Zhang, Zhi Cui, Cui-jiao Ma, Yu-ling Li, Hua Lu, Hong-yan Wu… in BMC Cancer (2023)

Article

Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity

Ligand-induced receptor dimerization or oligomerization is a widespread mechanism for ensuring communication specificity, safeguarding receptor activation, and facilitating amplification of signal transduction...

Yan Sun, **u-Na Yang, Shuang-Shuang Yang… in Signal Transduction and Targeted Therapy (2023)

Article

Using machine learning-based radiomics to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes

To establish a machine learning-based radiomics model to differentiate between glioma and solitary brain metastasis from lung cancer and its subtypes, thereby achieving accurate preoperative classification.

Feng-Ying Zhu, Yu-Feng Sun, **ao-** Yin, Yu Zhang, Li-Hong **ng… in Discover Oncology (2023)

Article

ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis

Ankyrin repeat domain 49 (ANKRD49) has been found to be highly expressed in multiple cancer including lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC). However, the function of ANKRD49 in the path...

Jia Sun, **-rui Hu, Chao-feng Liu, Yuan Li, Wei Wang, Rong Fu, Min Guo… in BMC Cancer (2023)

Article

Metatranscriptome of human lung microbial communities in a cohort of mechanically ventilated COVID-19 Omicron patients

The Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) infected a substantial proportion of Chinese population, and understanding the factors underlying the severity of the dis...

Lin Wang, Jia-Bao Cao, Bin-Bin **a, Yue-Juan Li… in Signal Transduction and Targeted Therapy (2023)

Article

TMEM147 aggravates the progression of HCC by modulating cholesterol homeostasis, suppressing ferroptosis, and promoting the M2 polarization of tumor-associated macrophages

The endoplasmic reticulum (ER) regulates critical processes, including lipid synthesis, which are affected by transmembrane proteins localized in the ER membrane. One such protein, transmembrane protein 147 (T...

**g**g Huang, Huayang Pan, **g Sun… in Journal of Experimental & Clinical Cancer … (2023)