-
Article
Open AccessDynamic changes in glymphatic function in reversible cerebral vasoconstriction syndrome
The pathophysiology of the reversible cerebral vasoconstriction syndrome (RCVS) remains enigmatic and the role of glymphatics in RCVS pathophysiology has not been evaluated. We aimed to investigate RCVS glymph...
-
Article
Open AccessCebp1 and Cebpβ transcriptional axis controls eosinophilopoiesis in zebrafish
Eosinophils are a group of granulocytes well known for their capacity to protect the host from parasites and regulate immune function. Diverse biological roles for eosinophils have been increasingly identified...
-
Article
Open AccessSweet taste receptors play roles in artificial sweetener-induced enhanced urine output in mice
Sweet taste receptors found in oral and extra oral tissues play important roles in the regulation of many physiological functions. Studies have shown that urine volume increases during the lifetime exposure to...
-
Article
Automated identification and quantification of metastatic brain tumors and perilesional edema based on a deep learning neural network
This paper presents a deep learning model for use in the automated segmentation of metastatic brain tumors and associated perilesional edema.
-
Article
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway
Dry eye disease (DED) is a prevalent ocular disorder with a multifactorial etiology. The pre-angiogenic and pre-inflammatory milieu of the ocular surface plays a critical role in its pathogenesis. DZ2002 is a ...
-
Chapter
Förderung einer qualitativ hochwertigen Talentausbildung durch eine integrierte Studiengangs-, Beschäftigungs- und Wirtschaftsentwicklung
Die Ausrichtung auf die wirtschaftliche Entwicklung, die Optimierung der Studiengangstrukturen, die Vertiefung der Zusammenarbeit zwischen Hochschulen und Unternehmen, die Reform der Mechanismen der Talentausb...
-
Article
Open AccessSteam caps in geothermal reservoirs can be monitored using seismic noise interferometry
Harvesting geothermal energy often leads to a pressure drop in reservoirs, decreasing their profitability and promoting the formation of steam caps. While steam caps are valuable energy resources, they also al...
-
Article
Noninvasive investigations of human glymphatic dynamics in a diseased model
To explore human glymphatic dynamics in a diseased model via a noninvasive technique.
-
Article
Implications for the supermassive black hole binaries from the NANOGrav 15-year data set
Several pulsar timing array (PTA) collaborations, including NANOGrav, EPTA, PPTA, and CPTA, have announced the evidence for a stochastic signal consistent with a stochastic gravitational wave background (SGWB)...
-
Article
Density functional theory studies on the structures and NO molecule adsorption and dissociation of RhmPdn (m + n = 13) clusters
Density functional theory (DFT) studies are performed on the geometric structures, stability, electronic properties of the RhmPdn (m + n = 13) clusters. All the configurations are 13-atomic icosahedral structures...
-
Article
Progress of Metal Nanomaterial Controllable Preparation by Photoreduction
Metal nanoparticles (NPs) are widely used in biomedicine, catalysis, environment, electronics, and other fields, which is closely related to its structural form. For this purpose, researchers have been looking...
-
Article
Treatment and survival of patients with small cell lung cancer and brain metastasis
To elucidate treatment patterns and their outcomes in patients with small cell lung cancer (SCLC) and brain metastasis (BM).
-
Article
Quality and consistency of clinical practice guideline recommendations for PET/CT and PET: a systematic appraisal
To systematically appraise the methodologies used for guidelines for positron emission tomography (PET) imaging and to compare the consistency of these recommendations.
-
Article
Open AccessImprovement of Learning and Memory by Elevating Brain D-Aspartate in a Mouse Model of Fragile X Syndrome
Fragile X syndrome (FXS) is an inherited human mental retardation that arises from expansion of a CGG repeat in the Fmr1 gene, causing loss of the fragile X mental retardation protein (FMRP). It is reported that ...
-
Article
Functional disruptions of the brain network in low back pain: a graph-theoretical study
The aim of this study was to investigate alterations in the topological organization of whole-brain functional networks in patients with chronic low back pain (CLBP) and characterize the relationship of these ...
-
Article
Hypertension Treatment in Frail Older Adults: A Systematic Review and Appraisal of Guidelines
Managing hypertension in frail older patients is challenging. Several institutions and organizations have published up-to-date hypertension guidelines suggesting frailty screening among older hypertensive pati...
-
Article
Review on the strategies for enhancing mechanical properties of bacterial cellulose
Bacterial cellulose (BC) is a pure biopolymer with abundant sources. BC has been used in wound dressings, artificial blood vessels, bone tissue engineering, and other applications because of its microporosity,...
-
Article
Open AccessA niche-mimicking polymer hydrogel-based approach to identify molecular targets for tackling human pancreatic cancer stem cells
Pancreatic adenocarcinoma (PAAD) is one of the most fatal human cancers, but effective therapies remain to be established. Cancer stem cells (CSCs) are highly resistant to anti-cancer drugs and a deeper unders...
-
Article
Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer
Thymidine kinase 1 (TK1) level is an independent survival prognostic factor for both premalignant and malignant cervical pathologies. Herein, this study sought to probe the impacts of TK1 on cervical cancer (C...
-
Article
Is it advisable to perform radiosurgery for EGFR-TKI-controlled brain metastases? A retrospective study of the role of radiosurgery in lung cancer treatment
Given the availability of TKIs with high central nervous system efficacy, the question arises as to whether upfront SRS provides additional clinical benefits. The goal of this study was to characterize the cli...
