614 Result(s)
within
**a Zhai
Medicine & Public Health
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Article
Open AccessKIF22 promotes multiple myeloma progression by regulating the CDC25C/CDK1/cyclinB1 pathway
Multiple myeloma (MM) is an incurable hematological malignancy characterized by clonal proliferation of malignant plasma B cells in bone marrow, and its pathogenesis remains unknown. The aim of this study was ...
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Open AccessIdentification of immunogenic cell death-related damage-related molecular patterns (DAMPs) to predict outcomes in patients with head and neck squamous cell carcinoma
Head and neck cancer is the sixth most common type of cancer worldwide, wherein the immune responses are closely associated with disease occurrence, development, and prognosis. Investigation of the role of imm...
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Open AccessPredicting preoperative muscle invasion status for bladder cancer using computed tomography-based radiomics nomogram
The aim of the study is to assess the efficacy of the established computed tomography (CT)-based radiomics nomogram combined with radiomics and clinical features for predicting muscle invasion status in bladde...
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Open AccessMerkel cell carcinoma overlap** Bowen’s disease: two cases report and literature review
Merkel cell carcinoma (MCC) is a rare neuroendocrine tumor of the skin, which mainly occurs in the sun exposed sites of white patients over 65 years, with a higher recurrence and metastasis rate. Clinically, M...
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Open AccessA new TROP2-targeting antibody-drug conjugate shows potent antitumor efficacy in breast and lung cancers
Trophoblast cell surface antigen 2 (Trop2) is considered to be an attractive therapeutic target in cancer treatments. We previously generated a new humanized anti-Trop2 antibody named hIMB1636, and designated ...
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Open AccessUnusual cause of muscle weakness, type II respiratory failure and pulmonary hypertension: a case report of ryanodine receptor type 1(RYR1)-related myopathy
Patients with congenital myopathies may experience respiratory involvement, resulting in restrictive ventilatory dysfunction and respiratory failure. Pulmonary hypertension (PH) associated with this condition ...
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Open AccessAbnormal performance of peroral endoscopic myotomy (POEM): a case misdiagnosed as achalasia of cardia
Pseudoachalasia is a rare disease that behaves similarly to achalasia (AC), making it sometimes difficult to differentiate.
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Open AccessGenetically predicted dietary macronutrient intakes and atrial fibrillation risk: a Mendelian randomization study
Previous observational investigations have indicated a potential association between relative dietary macronutrient intakes and atrial fibrillation and flutter (AF) risk. In this study, we employed Mendelian R...
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Open AccessComparison of the effect of ultrasounic-harmonic scalpel and electrocautery in the treatment of axillary lymph nodes during radical surgery for breast cancer
To compare the efficacy of ultrasounic-harmonic scalpel and electrocautery in the treatment of axillary lymph nodes during radical surgery for breast cancer.
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Article
Open AccessThe value of machine learning based on CT radiomics in the preoperative identification of peripheral nerve invasion in colorectal cancer: a two-center study
We aimed to explore the application value of various machine learning (ML) algorithms based on multicenter CT radiomics in identifying peripheral nerve invasion (PNI) of colorectal cancer (CRC).
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Open AccessChallenges and opportunities of deep learning for wearable-based objective sleep assessment
In recent years the intersection of wearable technologies and machine learning (ML) based deep learning (DL) approaches have highlighted their potential in sleep research. Yet, a recent study published in NPJ ...
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Open AccessUnveiling the therapeutic potential of Dl-3-n-butylphthalide in NTG-induced migraine mouse: activating the Nrf2 pathway to alleviate oxidative stress and neuroinflammation
Migraine stands as a prevalent primary headache disorder, with prior research highlighting the significant involvement of oxidative stress and inflammatory pathways in its pathogenesis and chronicity. Existing...
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Open AccessExploration of vitamin D metabolic activity-related biological effects and corresponding therapeutic targets in prostate cancer
Previous studies have unequivocally demonstrated that the vitamin D (VD) metabolism pathway significantly influences prognosis and sensitivity to hormone therapy in prostate cancer (PCa). However, the precise ...
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Open AccessThe influence of physical activity on internet addiction among Chinese college students: the mediating role of self-esteem and the moderating role of gender
The significance of self-esteem in the relationship between physical activity and Internet addiction among college students cannot be over, as it lays a solid foundation for the prevention and control of Inter...
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Open AccessCompetency scale of quality and safety for greenhand nurses: instrument development and psychometric test
Guaranteeing nursing service safety and quality is a prioritized issue in the healthcare setting worldwide. However, there still lacks a valid scale to measure the quality and safety competencies of newly grad...
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Open AccessCan low-dose intravenous immunoglobulin be an alternative to high-dose intravenous immunoglobulin in the treatment of children with newly diagnosed immune thrombocytopenia: a systematic review and meta-analysis
Intravenous immunoglobulin (IVIg) is a first-line treatment for children with newly diagnosed immune thrombocytopenia (ITP). Higher doses of IVIg are associated with a more insupportable financial burden to pe...
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Open AccessHeart-brain axis: low blood pressure during off-pump CABG surgery is associated with postoperative heart failure
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Open AccessCorrection to: Loneliness among older Chinese individuals: the status quo and relationships with activity-related factors
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Open AccessExpression level of neutrophil extracellular traps in peripheral blood of patients with chronic heart failure complicated with venous thrombosis and its clinical significance
Previous studies have reported that neutrophil extracellular traps (NETs) have been identified to be involved in thrombosis, but the clinical value in chronic heart failure (CHF) patients with venous thrombosi...
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Open AccessExploring functional dysconnectivity in schizophrenia: alterations in eigenvector centrality map** and insights into related genes from transcriptional profiles
Schizophrenia is a mental health disorder characterized by functional dysconnectivity. Eigenvector centrality map** (ECM) has been employed to investigate alterations in functional connectivity in schizophre...
