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Article
Data sampling and kernel manifold discriminant alignment for mixed-project heterogeneous defect prediction
Heterogeneous defect prediction (HDP) refers to identifying more likely defect-proneness of software modules in a target project using heterogeneous metric data from other source projects, which solves the het...
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Article
Salt-inducible kinase 1-CREB-regulated transcription coactivator 1 signalling in the paraventricular nucleus of the hypothalamus plays a role in depression by regulating the hypothalamic–pituitary–adrenal axis
Elucidating the molecular mechanism underlying the hyperactivity of the hypothalamic–pituitary–adrenal axis during chronic stress is critical for understanding depression and treating depression. The secretion...
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Article
Open AccessSpatially resolved gene regulatory and disease-related vulnerability map of the adult Macaque cortex
Single cell approaches have increased our knowledge about the cell type composition of the non-human primate (NHP), but a detailed characterization of area-specific regulatory features remains outstanding. We ...
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Article
Open AccessHarmonics-assisted optical phase amplifier
The change in the relative phase between two light fields serves as a basic principle for the measurement of the physical quantity that guides this change. It would therefore be highly advantageous if the rela...
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Article
Open AccessMicroglial debris is cleared by astrocytes via C4b-facilitated phagocytosis and degraded via RUBICON-dependent noncanonical autophagy in mice
Microglia are important immune cells in the central nervous system (CNS) that undergo turnover throughout the lifespan. If microglial debris is not removed in a timely manner, accumulated debris may influence ...
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Article
BAP31 affects macrophage polarization through regulating helper T cells activation
Previously, we reported that B cell receptor associated protein 31 (BAP31) is a positive regulator on T-cells activation. Helper T cells [cluster of differentiation 4+ (CD4+) T cells] can regulate macrophage acti...
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Article
Thiacalix[4]arene-based complex with Co(II) ions as electrode modifier for simultaneous electrochemical determination of Cd(II), Pb(II), and Cu(II)
A complex [Co4(TCTA)2(H2O)8]∙10H2O (Co-TCTA) based on thiacalix[4]arene derivative has been synthesized for the first time using the solvothermal method. The glassy carbon electrode (GCE) modified with Co-TCTA (C...
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Article
Spectrally multiplexed and bright entangled photon pairs in a lithium niobate microresonator
On-chip bright quantum sources with multiplexing ability are extremely high in demand for integrated quantum networks with unprecedented scalability and complexity. Here, we demonstrate a bright and broadband ...
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Article
Open AccessPLCL1 regulates fibroblast-like synoviocytes inflammation via NLRP3 inflammasomes in rheumatoid arthritis
Phospholipase C-like 1 (PLCL1), a protein that lacks catalytic activity, has similar structures to the PLC family. The aim of this research was to find the function and underlying mechanisms of PLCL1 in fibrob...
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Article
Open AccessmiR-188-3p-targeted regulation of ATG7 affects cell autophagy in patients with nonobstructive azoospermia
Nonobstructive azoospermia (NOA) is one of the most difficult forms of male infertility to treat, and its pathogenesis is still unclear. miRNAs can regulate autophagy by affecting their target gene expression....
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Article
Open AccessEffects of resistance training on body composition and physical function in elderly patients with osteosarcopenic obesity: a systematic review and meta-analysis
Osteosarcopenic obesity (OSO) is a complex disease commonly seen in the elderly. We found that resistance training may improve bone mineral density, skeletal muscle mass, and body fat percentage in patients wi...
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Article
Engineering of electrolyte ion channels in MXene/holey graphene electrodes for superior supercapacitive performances
MXene has given great promises to supercapacitor electrode material due to its high conductivity and redox properties. However, the self-agglomeration of the MXene lamella will reduce its contact area with the...
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Article
Orelabrutinib-bruton tyrosine kinase inhibitor-based regimens in the treatment of central nervous system lymphoma: a retrospective study
Background. Central nervous system lymphoma (CNSL) is an aggressive lymphoma. Orelabrutinib, an oral Bruton tyrosine kinase inhibitor, is a new treatment strategy for CNSL. This study aims to evaluate the efficac...
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Article
Open AccessAuthor Correction: Development and clinical deployment of a smartphone-based visual field deep learning system for glaucoma detection
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Article
Establishment of a PCR Method for the Identification of Mink-Derived Components in Common Edible Meats
In this study, we established a DNA extraction method of meats and a PCR method for the detection of mink-derived components in common edible meats. The DNA of meats was extracted by a developed mink-derived c...
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Article
Open AccessIncreased MCL-1 synthesis promotes irradiation-induced nasopharyngeal carcinoma radioresistance via regulation of the ROS/AKT loop
Worldwide, nasopharyngeal carcinoma (NPC) is a rare head and neck cancer; however, it is a common malignancy in southern China. Radiotherapy is the most important treatment strategy for NPC. However, although ...
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Article
Simultaneous electrochemical detection of gallic acid and uric acid with p-tert-butylcalix[4]arene-based coordination polymer/mesoporous carbon composite
Design and synthesis of an efficient electrocatalyst for simultaneous determination of gallic acid (GA) and uric acid (UA) is vital in the biological field. Herein, we synthesized a new p-tert-butylcalix[4]arene-...
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Article
Open AccessRole of the S100 protein family in rheumatoid arthritis
Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by synovial hyperplasia, inflammatory cell infiltration, and proliferation of inflammatory tissue (angiogranuloma). The destruction o...
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Chapter and Conference Paper
Research on Radar Anti-jamming Performance Evaluation System in Complex Electromagnetic Environment
There are problems of large limitations and different standards in the evaluation of interference resistance performance of radar and other information equipment in complex electromagnetic environments. We con...
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Protocol
A CRISPR-Based Method for Constructing Conditional Mutations of Essential Genes in Cyanobacteria
Cyanobacteria, a group of diverse bacteria capable of oxygenic photosynthesis, are excellent models for investigating many important cellular processes, such as photosynthesis, nitrogen fixation, and prokaryot...
