-
Chapter and Conference Paper
Development and Performance Evaluation of High Strength and High Temperature Resistant Plugging System for Repairing Casing Damage
Cement slurry used for plugging in casing damage has long been faced with problems such as low strength, weak corrosion resistance, and low one-time successful rate. It is urgent to develop new plugging materi...
-
Article
Clinical features, prognostic stratification, and treatment of advanced-stage non-nasal type extranodal natural killer/T-cell lymphoma: a multi-institutional real-world study
The present study aimed to investigate the clinical features, prognosis, and treatment of advanced-stage non-nasal type extranodal natural killer/T-cell lymphoma (ENKTCL). This real-world study retrospectively...
-
Article
The benefit of omeprazole exposure on all-cause mortality and length of ICU/hospital stay might vary with age in critically ill pediatric patients: A cohort study
To investigate the association between proton pump inhibitors (PPIs) administration during hospitalization and mortality and length of stay in critically ill pediatric patients.
-
Article
Open AccessProteomic characterization of epithelial ovarian cancer delineates molecular signatures and therapeutic targets in distinct histological subtypes
Clear cell carcinoma (CCC), endometrioid carcinoma (EC), and serous carcinoma (SC) are the major histological subtypes of epithelial ovarian cancer (EOC), whose differences in carcinogenesis are still unclear....
-
Article
PSA study of the effect of extreme snowfall on a floating nuclear power plant: case study in the Bohai Sea
This study presents a probabilistic safety analysis (PSA) method for the external event of extreme snowfall on a floating nuclear power plant (FNPP) deployed in the Bohai Sea. We utilized the Weibull and Gumbe...
-
Article
Open AccessCommon pathogenic bacteria-induced reprogramming of the host proteinogenic amino acids metabolism
Apart from cancer, metabolic reprogramming is also prevalent in other diseases, such as bacterial infections. Bacterial infections can affect a variety of cells, tissues, organs, and bodies, leading to a serie...
-
Article
Integrative analysis reveals that SLC38A1 promotes hepatocellular carcinoma development via PI3K/AKT/mTOR signaling via glutamine mediated energy metabolism
Although hepatocellular carcinoma (HCC) is rather frequent, little is known about the molecular pathways underlying its development, progression, and prognosis. In the current study, we comprehensively analyze...
-
Article
Open AccessComposition of pathogenic microorganism in chronic osteomyelitis based on metagenomic sequencing and its application value in etiological diagnosis
Traditionally, conventional microbiological culture methods have been used to detect pathogenic microorganisms in chronic osteomyelitis. However, these methods have been found to have a low detection rate, com...
-
Article
Open AccessGut microbiota impacts bone via Bacteroides vulgatus-valeric acid-related pathways
Although the gut microbiota has been reported to influence osteoporosis risk, the individual species involved, and underlying mechanisms, remain largely unknown. We performed integrative analyses in a Chinese ...
-
Article
Winogradskyella immobilis sp. nov., an Alginate-Hydrolyzing Bacterium Isolated from the Brown Algae Saccharina japonica
A novel bacterium, designated E313T, was isolated from brown algae Saccharina japonica in Weihai, China. The strain is a Gram-stain-negative, non-flagellated, non-gliding, aerobic, rod-shaped bacterium that grows...
-
Article
Open AccessCD24+LCN2+ liver progenitor cells in ductular reaction contributed to macrophage inflammatory responses in chronic liver injury
CD24+CK19+/CD24+SOX9+ resident liver cells are activated and expanded after chronic liver injury in a ductular reaction. However, the sources and functions of these cells in liver damage remain disputed.
-
Article
Targeting Vascular Smooth Muscle Cell Senescence: A Novel Strategy for Vascular Diseases
Vascular diseases are a major threat to human health, characterized by high rates of morbidity, mortality, and disability. VSMC senescence contributes to dramatic changes in vascular morphology, structure, and...
-
Article
Enhancing the terrain adaptability of a multirobot cooperative transportation system via novel connectors and optimized cooperative strategies
Given limited terrain adaptability, most existing multirobot cooperative transportation systems (MRCTSs) mainly work on flat pavements, restricting their outdoor applications. The connectors’ finite deformatio...
-
Article
Open AccessValue of Echocardiography and Cardiac Magnetic resonance in assessing left ventricular function in breast and gastric cancer patients after Anthracycline Chemotherapy
Echocardiography (ECHO) and cardiac magnetic resonance imaging (MRI) are used to observe changes in the left ventricular structure in patients with breast and gastric cancer after 6 cycles of chemotherapy. Bas...
-
Article
Open AccessFAM3 family genes are associated with prognostic value of human cancer: a pan-cancer analysis
Family with sequence similarity three member (FAM3) plays a crucial role in the malignant development of various cancers of human. However, there remains doubtful what specific role of FAM3 family genes in pan...
-
Article
Open AccessEffect of lifestyle or metformin interventions before IVF/ICSI treatment on infertile women with overweight/obese and insulin resistance: a factorial design randomised controlled pilot trial
For infertile women with overweight/obesity and insulin resistance (IR), it is uncertain whether intervention before infertility treatment can improve live birth rate (LBR). We implemented a factorial-design s...
-
Article
Cordythiazole A, the first member of thiazole alkaloids from Chinese cordyceps, with α-glucosidase inhibitory activity
Chinese cordyceps, also known as Dong-Chong-**a-Cao, is widely recognized as a famous precious tonic herb, and used as traditional Chinese medicine for centuries. It is mainly used for regulating the immune sy...
-
Article
Open AccessA novel mutation in intron 1 of Wnt1 causes developmental loss of dopaminergic neurons in midbrain and ASD-like behaviors in rats
Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with a strong genetic liability. Despite extensive studies, however, the underlying pathogenic mechanism still remains elusive. In the ...
-
Article
Open AccessA longitudinal resource for population neuroscience of school-age children and adolescents in China
During the past decade, cognitive neuroscience has been calling for population diversity to address the challenge of validity and generalizability, ushering in a new era of population neuroscience. The develop...
-
Article
Modified constitutive behavior model of Mg-10Gd-3Y-0.4Zr alloy during high-temperature deformation process
To investigate the flow behavior of Mg-10Gd-3Y-0.4Zr magnesium alloy during high-temperature deformation, the thermal compression experiments were conducted in the temperature range of 573–773 K and strain rat...
