48 Result(s)
within
English
Science, Humanities and Social Sciences, multidisciplinary
**-peng Pei
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessEnd-to-end vascular anastomosis using a novel magnetic compression device in rabbits: a preliminary study
Magnetic compression anastomosis (MCA) has been appreciated as an innovative alternative to manual suturing in vascular reconstruction. However, magnetic devices have limitations in their applications. The pre...
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Article
Open AccessRelative posture between head and finger determines perceived tactile direction of motion
The hand explores the environment for obtaining tactile information that can be fruitfully integrated with other functions, such as vision, audition, and movement. In theory, somatosensory signals gathered by ...
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Article
Open AccessInitial radiographic tracheal ratio in predicting clinical outcomes in croup in children
Croup is the leading infectious disease resulting in pediatric upper airway obstruction. Our purpose is to analyze diverse features of neck radiographs could be seen as an objective tool to predict outcomes in...
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Open AccessPlasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment
Levels of amyloid-β (Aβ) and tau peptides in brain have been associated with Alzheimer disease (AD). The current study investigated the abilities of plasma Aβ42 and total-tau (t-tau) levels in predicting cogni...
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Open AccessThe p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer
The biological role of miR-500a-5p has not yet been reported in the context of colorectal cancer (CRC). Here, we show that miR-500a-5p expression is decreased in CRC tissues compared with adjacent normal tissu...
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Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Accurate repair of DNA double-stranded breaks by homologous recombination preserves genome integrity and inhibits tumorigenesis. Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that activates innate i...
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Open AccessSpatial-temporal dynamics of carbon emissions and carbon sinks in economically developed areas of China: a case study of Guangdong Province
This study analysed spatial-temporal dynamics of carbon emissions and carbon sinks in Guangdong Province, South China. The methodology was based on land use/land cover data interpreted from continuous high-res...
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Open AccessDietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
Grass carp (223.85–757.33 g) were fed diets supplemented with magnesium (73.54–1054.53 mg/kg) for 60 days to explore the impacts of magnesium deficiency on the growth and intestinal structural integrity of the...
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Article
Open AccessChemopreventive effects of Ku-** tea against AOM-induced precancerous colorectal lesions in rats and metabolomic analysis
Ku-** tea (KJT) is a health beverage prepared from the leaves of the plant Acer tataricum subsp. ginnala that has been consumed in some regions of China for thousands of years. KJT contains high levels of anti-i...
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Open AccessAlleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression
Fluoxetine, one of the selective serotonin reuptake inhibitor (SSRI) antidepressants, has been thought to be effective for treating post-stroke depression (PSD). Recent work has shown that fluoxetine may exert...
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Article
Open AccessCDK5-mediated phosphorylation of XBP1s contributes to its nuclear translocation and activation in MPP+-induced Parkinson’s disease model
Parkinson’s disease (PD) is an irreversible and progressive neurodegenerative disorder characterized by the selective loss of dopaminergic neurons of the substantia nigra pars compacta. Growing evidence indica...
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Open AccessThree dimensional printing of calcium sulfate and mesoporous bioactive glass scaffolds for improving bone regeneration in vitro and in vivo
In the clinic, bone defects resulting from infections, trauma, surgical resection and genetic malformations remain a significant challenge. In the field of bone tissue engineering, three-dimensional (3D) scaff...
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Article
Open AccessRenal Denervation Improves the Baroreflex and GABA System in Chronic Kidney Disease-induced Hypertension
Hypertensive rats with chronic kidney disease (CKD) exhibit enhanced gamma-aminobutyric acid (GABA)B receptor function and regulation within the nucleus tractus solitarii (NTS). For CKD with hypertension, renal d...
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Article
Open AccessEvolutionary trajectories of snake genes and genomes revealed by comparative analyses of five-pacer viper
Snakes have numerous features distinctive from other tetrapods and a rich history of genome evolution that is still obscure. Here, we report the high-quality genome of the five-pacer viper, Deinagkistrodon acutus
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Open AccessDiscovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways
Inhibition of angiogenesis is considered as one of the desirable pathways for the treatment of tumor growth and metastasis. Herein we demonstrated that a series of pyridinyl-thiazolyl carboxamide derivatives w...
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Article
Open AccessCombination of deep eutectic solvent and ionic liquid to improve biocatalytic reduction of 2-octanone with Acetobacter pasteurianus GIM1.158 cell
The efficient anti-Prelog asymmetric reduction of 2-octanone with Acetobacter pasteurianus GIM1.158 cells was successfully performed in a biphasic system consisting of deep eutectic solvent (DES) and water-immisc...
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Article
Open AccessResveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension
Recent studies have reported that the activation of AMP-activated protein kinase (AMPK) suppressed oxidative stress. The aim of this study was to examine whether the activation of AMPK in the brain decreased R...
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Open AccessIntegrative topological analysis of mass spectrometry data reveals molecular features with clinical relevance in esophageal squamous cell carcinoma
Combining MS-based proteomic data with network and topological features of such network would identify more clinically relevant molecules and meaningfully expand the repertoire of proteins derived from MS anal...
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Open AccessMid-infrared laser emission from Cr:ZnS channel waveguide fabricated by femtosecond laser helical writing
The operation of a mid-infrared laser at 2244 nm in a Cr:ZnS polycrystalline channel waveguide fabricated using direct femtosecond laser writing with a helical movement technique is demonstrated. A maximum pow...
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Open AccessCognitive dysfunction and health-related quality of life among older Chinese
We aimed to assess the association of cognitive dysfunction with health-related quality of life (HRQOL) among older adults in China. We analyzed community-based cross-sectional data of 5,557 Chinese individual...
