3,924 Result(s)
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English
**-cheng Huang
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Article
Neonatal neurological disorders involving the brainstem: neurosonographic approaches through the squamous suture and the foramen magnum
Brainstem damage which often indicates a critical condition is usually underestimated by trans-anterior-fontanel neurosonography (NS) owing to the far-field limitations. Instead, NS alternately scanning throug...
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Article
Open AccessEstimating Driving Performance Based on EEG Spectrum Analysis
The growing number of traffic accidents in recent years has become a serious concern to society. Accidents caused by driver's drowsiness behind the steering wheel have a high fatality rate because of the marke...
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Article
Modular organization of SARS coronavirus nucleocapsid protein
The SARS-CoV nucleocapsid (N) protein is a major antigen in severe acute respiratory syndrome. It binds to the viral RNA genome and forms the ribonucleoprotein core. The SARS-CoV N protein has also been sugges...
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Article
Opposite effect of ERK1/2 and JNK on p53-independent p21WAF1/CIP1 activation involved in the arsenic trioxide-induced human epidermoid carcinoma A431 cellular cytotoxicity
While arsenic trioxide (As2O3) is an infamous carcinogen, it is also an effective chemotherapeutic agent for acute promyelocytic leukemia and some solid tumors. In human epidermoid carcinoma A431 cells, we found ...
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Article
Gene expression analysis of human hepatocellular carcinoma by using full-length cDNA library
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Hepatitis B virus (HBV) or hepatitis C virus (HCV) infection has been shown to cause hepatic carcinogenesis. A total 58,251 of cDNA clones ...
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Article
Tumor necrosis factor- \(\alpha\) induces caspase-independent cell death in human neutrophils via reactive oxidants and associated with calpain activity
Apoptosis mediated by caspase activation is important in the neutrophil homeostasis and resolution of tissue inflammation. Paradoxically, our previous study demonstrated that broad-spectrum caspase inhibition ...
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Article
Open AccessIntraprostatic injection of botulinum toxin type- A relieves bladder outlet obstruction in human and induces prostate apoptosis in dogs
With the increasing interest with botulinum toxin – A (BTX-A) application in the lower urinary tract, we investigated the BTX-A effects on the canine prostate and also in men with bladder outlet obstruction (B...
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Article
Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility
The reproductive hormone, estrogen, contributes to the development of breast cancer by binding to the estrogen receptor (ER) in the nucleus, triggering cell growth and tumor promotion. In addition to its role ...
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Article
Liver Hepcidin and Stainable Iron Expression in Biliary Atresia
Hepcidin is a proposed mammalian host defense peptide that was identified on the basis of its antimicrobial activity, but it was later shown to be a crucial regulator of iron homeostasis and a mediator of the ...
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Article
A mouse prostate cancer model induced by Hedgehog overexpression
Hedgehog is a regulatory protein during embryonic development and its abnormal activation in adult tissues has been implicated in tumorigenesis within sites where epithelial–mesenchymal interactions take place...
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Article
Ca2+ sparks and Ca2+ glows in superior cervical ganglion neurons
Ca2+ release from the endoplasmic reticulum (ER) is an integral component of neuronal Ca2+ signaling. The present study is to investigate properties of local Ca2+ release events in superior cervical ganglion (SCG...
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Article
Increasing incidence of diagnosed type 2 diabetes in Taiwan: analysis of data from a national cohort
Epidemiological evidence shows an increasing prevalence of type 2 diabetes in Taiwan. The aim of this study was to assess the yearly incidence for this country during 1992–1996.
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Article
The Three Networks Framework to Deal with Public Health Emergencies in Guangxi, China
To improve the detection and control of infectious diseases in Guangxi, China.
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Article
Open AccessEstimations of the S-wave velocity structures in Chia-Yi City, Taiwan, using the array records of microtremors
Shear-wave velocities (VS) have been widely used for the site characterization of earthquake ground motion. We report here our investigation of the S-wave velocity structures of Chia-Yi City, Taiwan using the arr...
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Article
Beneficial effects of LK-4, an analog of dextromethorphan on lipopolysaccharide-induced sepsis in rats
Dextromethorphan (DM), an anti-tussive agent, has been claimed to have anti-inflammatory and immunomodulatory effects in vitro. In our preliminary screening test, LK-4, an analog of DM, can afford more protection...
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Article
Open AccessSemantic Context Detection Using Audio Event Fusion
Semantic-level content analysis is a crucial issue in achieving efficient content retrieval and management. We propose a hierarchical approach that models audio events over a time series in order to accomplish...
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Article
De novo 617G–A nucleotide mutation in the ACVR1 gene in a Taiwanese patient with fibrodysplasia ossificans progressiva
Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disease with autosomal dominant transmission characterized by the presence of malformations of the big toes and of postnatal progressive heterot...
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Article
Open AccessRINGdb: An integrated database for G protein-coupled receptors and regulators of G protein signaling
Many marketed therapeutic agents have been developed to modulate the function of G protein-coupled receptors (GPCRs). The regulators of G-protein signaling (RGS proteins) are also being examined as potential d...
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Chapter and Conference Paper
Function-Level Multitasking Interface Design in an Embedded Operating System with Reconfigurable Hardware
Reconfigurable architecture provides a high performance computing paradigm. We can implement the compute-intensive functions into reconfigurable devices to optimize the application performance. In current reco...
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Chapter and Conference Paper
A Mental Workload Predicator Model for the Design of Pre Alarm Systems
This study investigated the operator’s mental workload of the fourth Nuclear Power Plant in Taiwan. An experiment including the primary and secondary tasks was designed to simulate the reactor shutdown procedu...
