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  1. Article

    Open Access

    Proton-transfer-induced 3D/2D hybrid perovskites suppress ion migration and reduce luminance overshoot

    Perovskite light-emitting diodes (PeLEDs) based on three-dimensional (3D) polycrystalline perovskites suffer from ion migration, which causes overshoot of luminance over time during operation and reduces its o...

    Hobeom Kim, Joo Sung Kim, Jung-Min Heo, Mingyuan Pei in Nature Communications (2020)

  2. Article

    Open Access

    Epithelial-mesenchymal transition gene signature is associated with prognosis and tumor microenvironment in head and neck squamous cell carcinoma

    In this study we assessed the clinical significance of an epithelial-mesenchymal transition (EMT) gene signature and explored its association with the tumor microenvironment related to immunotherapy in patient...

    Ah Ra Jung, Chan-Hun Jung, Joo Kyung Noh, Young Chan Lee in Scientific Reports (2020)

  3. Article

    Open Access

    Near-field sub-diffraction photolithography with an elastomeric photomask

    Photolithography is the prevalent microfabrication technology. It needs to meet resolution and yield demands at a cost that makes it economically viable. However, conventional far-field photolithography has re...

    Sangyoon Paik, Gwangmook Kim, Sehwan Chang, Sooun Lee, Dana ** in Nature Communications (2020)

  4. Article

    Open Access

    Bioinformatic analysis of peripheral blood RNA-sequencing sensitively detects the cause of late graft loss following overt hyperglycemia in pig-to-nonhuman primate islet xenotransplantation

    Clinical islet transplantation has recently been a promising treatment option for intractable type 1 diabetes patients. Although early graft loss has been well studied and controlled, the mechanisms of late gr...

    Hyun-Je Kim, Ji Hwan Moon, Hyunwoo Chung, Jun-Seop Shin, Bongi Kim in Scientific Reports (2019)

  5. Article

    Open Access

    Risk factors of postoperative major adverse cardiac events after radical cystectomy: implication of diastolic dysfunction

    Radical cystectomy, which is a standard treatment of muscle invasive and high-grade non-invasive bladder tumour, is accompanied with high rates of postoperative complications including major adverse cardiac ev...

    In-Jung Jun, Junghwa Kim, Hyun-Gyu Kim, Gi-Ho Koh, Jai-Hyun Hwang in Scientific Reports (2019)

  6. Article

    Open Access

    Optical characteristics of refractive-index-matching diffusion layer in organic light-emitting diodes

    We developed a diffusion layer with a refractive index-matching layer added to a transparent nanoscale polymer-based structure to obtain its effective scattering effects. The diffusion layer had higher haze wh...

    Cheol Hwee Park, Jae Geun Kim, Sun-Gyu Jung, Dong Jun Lee in Scientific Reports (2019)

  7. Article

    Open Access

    Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential

    Macrophages are responsible for innate and adaptive immune response activation necessary for eliminating infections. Optimal activation of macrophages to phagocytize Mycobacterium tuberculosis is critical in anti...

    Hye-Soo Park, Yong Woo Back, Ki-Won Shin, Hyun Shik Bae, Kang-In Lee in Scientific Reports (2019)

  8. Article

    Open Access

    Author Correction: Effect of BI-1 on insulin resistance through regulation of CYP2E1

    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.

    Geum-Hwa Lee, Kyoung-** Oh, Hyung-Ryong Kim, Hye-Sook Han in Scientific Reports (2018)

  9. Article

    Open Access

    Discovery of glycocholic acid and taurochenodeoxycholic acid as phenotypic biomarkers in cholangiocarcinoma

    Although several biomarkers can be used to distinguish cholangiocarcinoma (CCA) from healthy controls, differentiating the disease from benign biliary disease (BBD) or pancreatic cancer (PC) is a challenge. CC...

    Won-Suk Song, Hae-Min Park, Jung Min Ha, Sung Gyu Shin, Han-Gyu Park in Scientific Reports (2018)

  10. Article

    Open Access

    Amelioration of Experimental autoimmune encephalomyelitis and DSS induced colitis by NTG-A-009 through the inhibition of Th1 and Th17 cells differentiation

    CD4+ T cells are the central for the mammalian adaptive immune system. Naïve CD4+ T cells mainly differentiate in to pro-inflammatory Th1, Th2 and Th17 cells upon antigenic stimulation. IFN-γ secreting Th1 cells ...

    Suman Acharya, Maheshwor Timilshina, Liyuan Jiang, Sabita Neupane in Scientific Reports (2018)

  11. Article

    Open Access

    Difference in virulence and composition of a cariogenic biofilm according to substratum direction

    The aim of this study was to investigate the difference in composition and virulence of Streptococcus mutans biofilms according to substratum direction. S. mutans biofilms (46-h-old) were formed on three differen...

    Minh-Huy Dang, Ji-Eun Jung, Hyeon-Mi Choi, Jae-Gyu Jeon in Scientific Reports (2018)

  12. Article

    Open Access

    SOX2 activation predicts prognosis in patients with head and neck squamous cell carcinoma

    SOX2 copy number and mRNA expression were analysed to examine the clinical significance of SOX2 activation in HNSCC. Gene expression signatures reflecting SOX2 activation were identified in an HNSCC cohort. Pa...

    Ji Hyun Chung, Hae Rim Jung, Ah Ra Jung, Young Chan Lee in Scientific Reports (2018)

  13. Article

    Open Access

    Assembly of “3D” plasmonic clusters by “2D” AFM nanomanipulation of highly uniform and smooth gold nanospheres

    Atomic force microscopy (AFM) nanomanipulation has been viewed as a deterministic method for the assembly of plasmonic metamolecules because it enables unprecedented engineering of clusters with exquisite cont...

    Kyung ** Park, Ji-Hyeok Huh, Dae-Woong Jung, **-Sung Park in Scientific Reports (2017)

  14. Article

    Open Access

    Chemical Structure of the Lipid A component of Pseudomonas sp. strain PAMC 28618 from Thawing Permafrost in Relation to Pathogenicity

    Climate change causes permafrost thawing, and we are confronted with the unpredictable risk of newly discovered permafrost microbes that have disease-causing capabilities. Here, we first characterized the deta...

    Han-Gyu Park, Ganesan Sathiyanarayanan, Cheol-Hwan Hwang, Da-Hee Ann in Scientific Reports (2017)

  15. Article

    Open Access

    Structural implications of Ca2+-dependent actin-bundling function of human EFhd2/Swiprosin-1

    EFhd2/Swiprosin-1 is a cytoskeletal Ca2+-binding protein implicated in Ca2+-dependent cell spreading and migration in epithelial cells. EFhd2 domain architecture includes an N-terminal disordered region, a PxxP m...

    Kyoung Ryoung Park, Min-Sung Kwon, Jun Yop An, Jung-Gyu Lee in Scientific Reports (2016)

  16. Article

    Open Access

    Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth

    Mycobacterium avium complex induces macrophage apoptosis. However, the M. avium components that inhibit or trigger apoptosis and their regulating mechanisms remain unclear. We recently identified the immunodomina...

    Kang-In Lee, Jake Whang, Han-Gyu Choi, Yeo-** Son, Haet Sal Jeon in Scientific Reports (2016)

  17. Article

    Open Access

    Silver Nanowire-IZO-Conducting Polymer Hybrids for Flexible and Transparent Conductive Electrodes for Organic Light-Emitting Diodes

    Solution-processed silver nanowire (AgNW) has been considered as a promising material for next-generation flexible transparent conductive electrodes. However, despite the advantages of AgNWs, some of their int...

    Ho Jun Yun, Se Jung Kim, Ju Hyun Hwang, Yong Sub Shim, Sun-Gyu Jung in Scientific Reports (2016)

  18. Article

    Open Access

    Effect of BI-1 on insulin resistance through regulation of CYP2E1

    Diet-induced obesity is a major contributing factor to the progression of hepatic insulin resistance. Increased free fatty acids in liver enhances endoplasmic reticulum (ER) stress and production of reactive o...

    Geum-Hwa Lee, Kyoung-** Oh, Hyung-Ryong Kim, Hye-Sook Han in Scientific Reports (2016)

  19. Article

    Open Access

    Large-area, continuous and high electrical performances of bilayer to few layers MoS2 fabricated by RF sputtering via post-deposition annealing method

    We report a simple and mass-scalable approach for thin MoS2 films via RF sputtering combined with the post-deposition annealing process. We have prepared as-sputtered film using a MoS2 target in the sputtering sy...

    Sajjad Hussain, Jai Singh, Dhanasekaran Vikraman, Arun Kumar Singh in Scientific Reports (2016)

  20. Article

    Open Access

    Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

    During replication, hepatitis C virus (HCV) utilizes macromolecules produced by its host cell. This process requires host cellular metabolic reprogramming to favor elevated levels of aerobic glycolysis. Theref...

    Gwon-Soo Jung, Jae-Han Jeon, Yeon-Kyung Choi, Se Young Jang in Scientific Reports (2016)

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