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Article
Application of next generation sequencing in the screening of monogenic diseases in China, 2021: a consensus among Chinese newborn screening experts
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Article
Open AccessAlterations of gut microbiota diversity, composition and metabonomics in testosterone-induced benign prostatic hyperplasia rats
Studies had shown many diseases affect the stability of human microbiota, but how this relates to benign prostatic hyperplasia (BPH) has not been well understood. Hence, this study aimed to investigate the reg...
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Article
Nonexudative morphologic changes of neovascularization on optical coherence tomography angiography as predictive factors for exudative recurrence in age-related macular degeneration
To evaluate morphologic changes of choroidal neovascularization (CNV) on optical coherence tomography angiography (OCTA) during the nonexudative period and to correlate the features and timing of recurrence in...
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Article
Open AccessRelationship between time of emergency department admission and adherence to the Surviving Sepsis Campaign bundle in patients with septic shock
Nighttime hospital admission is often associated with increased mortality risk in various diseases. This study investigated compliance rates with the Surviving Sepsis Campaign (SSC) 3-h bundle for daytime and ...
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Article
Open AccessRadiomics-based prediction of multiple gene alteration incorporating mutual genetic information in glioblastoma and grade 4 astrocytoma, IDH-mutant
In glioma, molecular alterations are closely associated with disease prognosis. This study aimed to develop a radiomics-based multiple gene prediction model incorporating mutual information of each genetic alt...
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Article
Open AccessCatheter ablation of atrial fibrillation in Korea: results from the Korean Heart Rhythm Society Ablation Registry for Atrial Fibrillation (KARA)
This study aims to investigate the current status of AF (atrial fibrillation) catheter ablation in Korea.
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Article
Validating respiratory index of auto-titrating positive airway pressure device with polysomnography
Positive airway pressure (PAP) devices have been widely used as the first line of treatment in obstructive sleep apnea (OSA). Most advanced PAP devices support the estimation of respiratory index (RI) using th...
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Article
Correction to: Diffusion and perfusion MRI may predict EGFR amplification and the TERT promoter mutation status of IDH-wildtype lower-grade gliomas
The original version of this article, published on 12 August 2020, unfortunately contained a mistake.
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Chapter
Dorsal Column Map**
to approach may cause dorsal column injury. Injury to the dorsal columns can result in dysfunction manifesting numbness, dysesthesias, proprioception changes, and sensory is a technique to identify the le...
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Article
Diffusion and perfusion MRI may predict EGFR amplification and the TERT promoter mutation status of IDH-wildtype lower-grade gliomas
Epidermal growth factor receptor (EGFR) amplification and telomerase reverse transcriptase promoter (TERTp) mutation status of isocitrate dehydrogenase-wildtype (IDHwt) lower-grade gliomas (LGGs; grade II/III)...
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Article
Open AccessThe GBA p.G85E mutation in Korean patients with non-neuronopathic Gaucher disease: founder and neuroprotective effects
Gaucher disease (GD) is caused by a deficiency of β-glucocerebrosidase, encoded by GBA. Haplotype analyses previously demonstrated founder effects for particular GBA mutations in Ashkenazi Jewish and French-Canad...
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Article
Open AccessInhibition of Chk1 by miR-320c increases oxaliplatin responsiveness in triple-negative breast cancer
Checkpoint kinase 1 (Chk1) expression is enhanced in most cancers owing to oncogenic activation and constant replicative stress. Chk1 inactivation is a promising cancer therapy, as its inactivation leads to ge...
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Article
RETRACTED ARTICLE: A Novel Method for the Prevention and Treatment of Small-for-Size Syndrome in Liver Transplantation
Currently there is no consensus on the optimal management of small-for-size syndrome following liver transplantation. Here we describe a technique to alleviate portal hypertension and improve the hepatocyte re...
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Article
Magnetic resonance imaging–based 3-dimensional fractal dimension and lacunarity analyses may predict the meningioma grade
To assess whether 3-dimensional (3D) fractal dimension (FD) and lacunarity features from MRI can predict the meningioma grade.
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Article
Open AccessCorrection to: Effects of robot-assisted gait training in patients with Parkinson’s disease: study protocol for a randomized controlled trial
An amendment to this paper has been published and can be accessed via the original article.
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Article
Open AccessCharacterization of splenic MRC1hiMHCIIlo and MRC1loMHCIIhi cells from the monocyte/macrophage lineage of White Leghorn chickens
Monocytes/macrophages, which are found in a variety of organs, maintain tissue homeostasis at a steady state and act as the first line of defence during pathogen-induced inflammation in the host. Most monocyte...
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Article
Validation and optimization of a web-based nomogram for predicting survival of patients with newly diagnosed glioblastoma
To optimize and validate a current (NRG [a newly constituted National Clinical Trials Network group through National Surgical Adjuvant Breast and Bowel Project [NSABP], the Radiation Therapy Oncology Group [RT...
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Article
Intravitreal aflibercept for submacular hemorrhage secondary to neovascular age-related macular degeneration and polypoidal choroidal vasculopathy
To evaluate the efficacy of intravitreal aflibercept monotherapy for submacular hemorrhage secondary to neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).
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Article
Amide proton transfer imaging might predict survival and IDH mutation status in high-grade glioma
To assess the utility of amide proton transfer (APT) imaging as an imaging biomarker to predict prognosis and molecular marker status in high-grade glioma (HGG, WHO grade III/IV).
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Article
Preoperative transcatheter arterial chemoembolization for surgical resection of huge hepatocellular carcinoma (≥ 10 cm): a multicenter propensity matching analysis
Surgical resection for hepatocellular carcinoma (HCC) is potentially curative, but long-term survival remains unsatisfactory. There is currently no effective neoadjuvant or adjuvant therapy for HCC. We sought ...