56 Result(s)

Article

Inhibition of p38 mitogen-activated protein kinases may attenuate scar proliferation after cleft lip surgery in rabbits via Smads signaling pathway

Cleft lip repair surgery always results in visible scarring. It has been proved that scar formation can be reduced by inhibiting the p38 mitogen-activated protein kinases (p38MAPKs) signaling pathway. However,...

Qian Ding, ** Yue, Ling-fa Xue, Yao-xiang Xu… in European Journal of Medical Research (2022)

Article

Which patients are prone to suffer liver metastasis? A review of risk factors of metachronous liver metastasis of colorectal cancer

In recent years, with the increasing incidence of colorectal cancer (CRC) and its high fatality rate, CRC has seized the attention of the world. And liver metastasis, as the main cause of death of CRC, has bec...

Mengdi Hao, Kun Wang, Yuhan Ding, Huimin Li… in European Journal of Medical Research (2022)

Article

Factors associated with left ventricular diastolic dysfunction in patients with septic shock

To investigate risk factors associated with left ventricular diastolic dysfunction (LVDD) of patients with septic shock.

Wei-Dong Ge, Feng-Zhi Li, Bang-Chuan Hu… in European Journal of Medical Research (2022)

Article

Exosome-mediated effects and applications in inflammatory diseases of the digestive system

Exosomes are membranous vesicles containing RNA and proteins that are specifically secreted in vivo. Exosomes have many functions, such as material transport and signal transduction between cells. Many studies...

**anli Wu, **aolin Xu, Yiwei **ang, Dongdong Fan… in European Journal of Medical Research (2022)

Article

LPCAT1 acts as an independent prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma

Lysophosphatidylcholine acyltransferase 1 (LPCAT1) is overexpressed in multiple human tumors. However, the role of LPCAT1 in hepatocellular carcinoma (HCC) has not been understood. We aim to explore the relati...

Lan Li, **ao Wang, Yanni Ding, Nini Hui, Bingjie Su… in European Journal of Medical Research (2022)

Article

Global trends and frontiers in research on coronary microvascular dysfunction: a bibliometric analysis from 2002 to 2022

Coronary microvascular dysfunction (CMD) is a leading cause of ischemic heart disease. Over the past few decades, considerable progress has been made with respect to research on CMD. The present study summariz...

**g Gao, Tiantian Meng, Min Li, Ruolin Du… in European Journal of Medical Research (2022)

Article

ASO Author Reflections: Are Older Patients with Proximal Femoral Bone Metastases Fit for Endoprosthetic Replacement?

Peng Liu MD, PhD, Zhuan Wang MD, Shiyuan Zhang MD… in Annals of Surgical Oncology (2022)

Article

Early predicting 30-day mortality in sepsis in MIMIC-III by an artificial neural networks model

Early identifying sepsis patients who had higher risk of poor prognosis was extremely important. The aim of this study was to develop an artificial neural networks (ANN) model for early predicting clinical out...

Yingjie Su, Cuirong Guo, Shifang Zhou, Changluo Li… in European Journal of Medical Research (2022)

Article

The ratio of monocytes to lymphocytes multiplying platelet predicts incidence of pulmonary infection-related acute kidney injury

Inflammation is a crucial factor in the pathogenesis and development of acute kidney injury (AKI). Macrophages, as an important innate immune cell, regulate immune response and play a pathophysiological role i...

Bo Shen, Zhou** Zou, Yang Li, ** Jia… in European Journal of Medical Research (2022)

Article

A c-MET-Targeted Topical Fluorescent Probe cMBP-ICG Improves Oral Squamous Cell Carcinoma Detection in Humans

The postoperative survival of oral squamous cell carcinoma (SCC) relies on precise detection and complete resection of original tumors. The mucosal extension of the tumor is evaluated visually during surgery, ...

**gbo Wang MD, Siyi Li MD, Kun Wang PhD, Ling Zhu MD… in Annals of Surgical Oncology (2023)

Article

The value of serum IL-4 to predict the survival of MDS patients

Immune indicators are routinely used for the detection of myelodysplastic syndrome (MDS), but these are not utilized as a reference indicator to assess prognosis in MDS-related prognostic evaluation systems, s...

Zhaoyun Liu, **ntong Xu, Likun Zheng, Kai Ding… in European Journal of Medical Research (2023)

Article

A prediction model for permanent pacemaker implantation after transcatheter aortic valve replacement

This study aims to develop a post-procedural risk prediction model for permanent pacemaker implantation (PPMI) in patients treated with transcatheter aortic valve replacement (TAVR).

Yiming Qi, **aolei Lin, Wenzhi Pan, **aochun Zhang… in European Journal of Medical Research (2023)

Article

A hypoxia- and lactate metabolism-related gene signature to predict prognosis of sepsis: discovery and validation in independent cohorts

High throughput gene expression profiling is a valuable tool in providing insight into the molecular mechanism of human diseases. Hypoxia- and lactate metabolism-related genes (HLMRGs) are fundamentally dysreg...

Yaojun Peng, Qiyan Wu, **nhuan Ding, Lingxiong Wang… in European Journal of Medical Research (2023)

Article

Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma

Melanoma is the deadliest form of skin tumor, and G protein-coupled receptors (GPCRs) play crucial roles in its carcinogenesis. Furthermore, the tumor microenvironment (TME) affects the overall survival (OS) a...

Kangjie Shen, Qiangcheng Wang, Lu Wang, Yang Yang… in European Journal of Medical Research (2023)

Article

Development and validation of a competitive risk model in patients with rectal cancer: based on SEER database

Rectal cancer is one of the most common malignancies. To predict the specific mortality risk of rectal cancer patients, we constructed a predictive nomogram based on a competing risk model.

Ruobing Hu, **uling Li, **aomin Zhou, Songze Ding in European Journal of Medical Research (2023)

Article

Clinical significance of interleukin-6, total bilirubin, CD3 + CD4 + T cells counts in the acute exacerbation of connective tissue disease-associated interstitial lung disease: a cross-sectional study

Interstitial lung disease (ILD) is a severe complication of connective tissue disease (CTD) that can significantly impact patients' prognosis and quality of life. However, the current diagnostic arena lacks re...

Chengxing Ma, Kaifang Meng, Shenyun Shi… in European Journal of Medical Research (2023)

Article

Lymphangiogenesis in gastric cancer: function and mechanism

Increased lymphangiogenesis and lymph node (LN) metastasis are thought to be important steps in cancer metastasis, and are associated with patient's poor prognosis. There is increasing evidence that the lympha...

Pengpeng Liu, **’an Ding, Chenyu Sun, Shuya Chen… in European Journal of Medical Research (2023)

Article

ASO Video Abstract: Neoadjuvant Chemo-Immunotherapy Increases Tumor Immune Lymphocytes Infiltration in Resectable NSCLC

Tianxiang Chen MD, Zhengqi Cao MD, Yingjia Sun MD… in Annals of Surgical Oncology (2023)

Article

A review on recent advances on nobiletin in central and peripheral nervous system diseases

In recent years, the role of nobiletin in neuronal disorders has received extensive attention. However, the study of nobiletin in the peripheral nervous system is limited. Nobiletin, as a compound with high fa...

Yueshan Pang, Juan **ong, You Wu, Weijun Ding in European Journal of Medical Research (2023)

Article

Mechanisms and biomarkers of immune-related adverse events in gastric cancer

Immune-checkpoint inhibitors (ICIs), different from traditional cancer treatment models, have shown unprecedented anti-tumor effects in the past decade, greatly improving the prognosis of many malignant tumors...

**’an Ding, Pengpeng Liu, Lingjiao Meng, Qun Zhao in European Journal of Medical Research (2023)