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Chapter and Conference Paper
Maternal Vascular Adaptation to Improve Oxygen Supply
Fetal arterial oxygen saturation, which may be considered a reliable indicator of fetal oxygenation, is controlled by the maternal placental blood flow. This can be theoretically derived with any degree of pre...
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Chapter and Conference Paper
Fetal Breathing Movements in Normoxia and in Hypoxia
I am delighted to be asked to prepare this chapter on fetal breathing movements since it was a German obstetrician, von Ahlfeld (1888), who more than a century ago recorded what he deduced (correctly we now kn...
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Chapter and Conference Paper
Influence of Maternal Oxygen Inhalation on Uteroplacental and Fetal Perfusion Measured by Doppler Sonography in Patients with Preterm Labor
It was the aim of the present study to confirm and to pursue our previous nuclear medical investigations (Ruckhäberle et al. 1986) by using the Doppler ultrasound method to measure the uteroplacental, fetoplac...
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Chapter and Conference Paper
Oxygen Supply to the Fetus and Fetal Hypoxemia
The fetus receives its oxygen supply across the placenta, to which oxygen is delivered by maternal blood. The amount of oxygen delivered to the placental site is determined by the magnitude of blood flow and t...
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Chapter and Conference Paper
The Role of the Sympathetic Nervous System in Preventing Brain Damage During Perinatal Asphyxia
Perinatal asphyxia is one of the major causes of cerebral hemorrhage, which is the most common form of brain damage in the neonatal period (Pape and Wigglesworth 1979). Since a number of clinical studies have ...
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Chapter and Conference Paper
Breathing Movements in the Human Fetus in Normoxia and Hypoxia
It was back in 1888 and 1905 that Ahlfeld published his observations of abdominal wall movements in pregnant women, which he interpreted as being caused by breathing movements carried out by the fetus. He said...
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Chapter and Conference Paper
Regional Abnormalities of Cerebral Energy Metabolism Following Birth Asphyxia
The technique of 31P nuclear magnetic resonance spectroscopy (31P MRS) has a number of unique features that make it particularly suitable for the study of abnormalities of cellular metabolism in vivo. The informa...
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Chapter and Conference Paper
Brain Blood Flow and the Dynamics of Circulatory Centralization During Acute Asphyxia in Intact and Chemically Sympathectomized Fetal Sheep
Acute fetal asphyxia caused by a reduction in uterine blood flow both increases sympathetic activity and decreases blood flow to peripheral organs, including the skin (Jensen and Berger 1991). These changes ar...
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Chapter and Conference Paper
Cardiovascular Effects of Endotoxin and Asphyxia in Fetal Sheep Near Term
A prospective sonographic study on the incidence of cerebral hemorrhage in 2781 babies born in our unit between 1984 and 1986 revealed that maternal signs of infection during parturition (temperature >38°C) ar...
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Chapter and Conference Paper
Regional Brain Blood Flow and Oxygen Delivery in Guinea Pig Fetuses Near Term
To examine brain blood flow and oxygen delivery to 14 brain regions in fetal guinea pigs near term, six fetuses were catheterized under general anesthesia of the dam on days 61–63 of pregnancy. In the control ...
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Chapter and Conference Paper
Role of Erythropoietin in the Regulation of Red Cell Production in Children Before and After Birth
An increasing number of hormones and cytokines are currently being recognized to influence maturation and differentiation of erythroid progenitor cells. Although their relative roles and complex interactions a...