51 Result(s)
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Chapter
Synthesis of cyclopsychotride by orthogonal ligation using unprotected peptide precursor
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Chapter
Cyclic peptides from unprotected precursors through ring-chain tautomerism
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Chapter
New Recombinant Bi- and Trispecific Antibody Derivatives
Bispecific antibodies (BsAb) are promising therapeutic tools in tomorrow’s medicine. When constructing BsAbs, the final molecular size should be large enough to avoid rapid renal clearing, but small enough to ...
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Chapter
Asparagine-Linked Glycosylational Modifications in Yeast
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Chapter
Arsenic induces oxidative DNA damage in mammalian cells
Although arsenic is a well-established human carcinogen, the underlying carcinogenic mechanism(s) is not known. Using the human-hamster hybrid (AL) cell mutagenic assay that is sensitive in detecting mutagens tha...
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Chapter
Cloning of Human Intestinal Taurine Transporter and Production of Polyclonal Antibody
Taurine (2-ethaneaminosulfonic acid, +NH3CH2CH2SO3) is an endogenous amino acid which functions as a modulator of transmembrane calcium transport, an osmoregulator and, putatively a free radical scavenger1. In ut...
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Chapter
The Discovery and Function of MTA1s in Eraα Cytoplasmic Sequestration
Cellular functions of estrogen receptor-α (ER) are mediated through mechanisms that are both dependent and independent of the nucleus. MTA1s, a recently identified naturally occurring isoform of metastasis ass...
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Chapter and Conference Paper
Joint Mechanics and Its Clinical Application
Human physical activity is influenced in a variety of ways by physiological conditions and psychomotor response. Joints are essential parts of the musculoskeletal system, connecting the skeletal structure and ...
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Chapter
Iron in mammals: pathophysiological mechanisms of overload and deficiency in relation to disease
The uptake of iron into the body is tightly regulated in humans and in other mammals. Mutations in key proteins that transport, sense, metabolize, and facilitate the utilization of iron cause perturbations in ...
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Chapter and Conference Paper
Using Efficient RBF Network to Identify Interface Residues Based on PSSM Profiles and Biochemical Properties
Protein-protein interactions play a very important role in many biological processes, for example, information transfer along signaling pathways, and enzyme catalysis. Recently, scientists tried to predict the...
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Chapter
T-DNA Insertion Mutants as a Resource for Rice Functional Genomics
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Chapter
Reconstruction and Structural Analysis of Metabolic and Regulatory Networks
Networks of interacting cellular components carry out the essential functions in living cells. Therefore, understanding the evolution and design principles of such complex networks is a central issue of system...
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Chapter
Engineering Blood-Contact Biomaterials by “H-Bond Grafting” Surface Modification
This review consists of two major parts: recollection of advances in therapeutic cardiovascular biomaterialsand a summary of “H-bond grafting” methodology for biocompatible/biofunctional surfacemodification of...
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Chapter
Histone Acetylation And Methylation
Post-synthetic modification of histone proteins in chromatin architecture plays a central role in the epigenetic regulation of transcription. Histone acetylation and methylation are the two major modifications...
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Chapter and Conference Paper
Differential-Expression Proteomics for the Study of Sulfur Metabolism in the Chemolithoautotrophic Acidithiobacillus ferrooxidans
Acidithiobacillus ferrooxidans obtains its energy from the oxidation of ferrous iron, elemental sulfur, or partially oxidized sulfur compounds. The ability of this microorganism to solubilize m...
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Chapter and Conference Paper
Ammonia-Induced Structural Changes of the Oxygen-Evolving Complex in Photosystem II Diminished at 277 K as Revealed by Light-Induced FTIR Difference Spectroscopy
We have applied light-induced FTIR difference spectroscopy to study NH3-induced structural changes of the oxygen-evolving complex in photosystem II. We found that NH3-induced spectral changes in the flash-induced...
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Chapter and Conference Paper
Characterization of a T-DNA Inserted STN8 Kinase Mutant of Oryza sativa L.
In Arabidopsis Two Stt7-Like Proteins Exist, Stn7 And Stn8. Loss Of Stn8 Kinase Blocks Photosystem Ii (Psii) Core Protein Phosphorylation Whereas Stn7 Is Required For Lhc Ii Phosphorylation. In This Work, A T-Dna...
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Chapter and Conference Paper
Allelopathic Inhibition by Scenedesmus obliquus of Photosynthesis and Growth of Microcystis aeruginosa
Microcystis aeruginosa is a species of unicellular cyanobacterium which synthesizes toxic microcystin. This work reports that the photosynthesis and growth of M. aeruginosa is inhibited by Scenedes...
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Chapter
AMPK Regulation of Cardiac Metabolism in Heart Disease
AMP-activated protein kinase (AMPK) plays an important role in regulating cardiac metabolism, and once stimulated, AMPK turns on ATP-generating mechanisms believed to be essential in maintaining a normal heart...
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Chapter and Conference Paper
Effect of Taurine on Antioxidant Enzyme System in B16F10 Melanoma Cells
There is now increasing evidence that free radicals and reactive oxygen species (ROS) are involved in a variety of pathological events. Reactive oxygen species are produced during normal cellular function and ...
