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Open AccessOverexpression of neurogenin1 induces neurite outgrowth in F11 neuroblastoma cells
Neurogenin1 (Ngn1) is a basic helix-loop-helix (bHLH) transcription factor expressed in neuronal precursors in the develo** nervous system. The function of Ngn1 in neurogenesis has been shown in various aspe...
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Article
Open AccessThe regulatory mechanism of phosphatidylinositol 3-kinase by insulin in 3T3 L1 fibroblasts: phosphorylation-independent activation of phosphatidylinositol 3-kinase
Phosphatidylinositol (PI) 3-kinase plays an important role in transducing the signals of various growth factor receptors. However, the regulatory mechanism of PI3-kinase activity by these growth factor recepto...
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Article
Open AccessRapid increase of cytosolic content of acetyl-CoA carboxylase isoforms in H9c2 cells by short-term treatment with insulin and okadaic acid
Mammalian acetyl-CoA carboxylase (ACC) is present in two isoforms, α and β, both of which catalyze formation of malonyl-CoA by fixing CO2 into acetyl-CoA. ACC-α is highly expressed in lipogenic tissues whereas...
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Article
Open AccessHeterogeneous HBV mutants coexist in Korean hepatitis B patients
Although many hepatitis B virus (HBV) mutants have been found in all open reading frames since the precore defective mutant was initially reported, systematic investigations of diverse HBV mutant populations i...
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Article
Open AccessEffects of cadmium on glucose transport in rat adipocytes and human erythrocytes: stimulation of GLUT1 catalytic activity
The effects of cadmium on facilitative glucose transporter function In rat adipocytes were studied. A short (30 min) incubation with cadmium resulted in stimulation of 3-O-methyl-D-glucose (3OMG ) equilibrium ...