21 Result(s)

Article

FHL1C induces apoptosis in notch1-dependent T-ALL cells through an interaction with RBP-J

Aberrantly activated Notch signaling has been found in more than 50% of patients with T-cell acute lymphoblastic leukemia (T-ALL). Current strategies that employ γ-secretase inhibitors (GSIs) to target Notch a...

Wei Fu, Kai Wang, Jun-Long Zhao, Heng-Chao Yu, San-Zhong Li, Yan Lin… in BMC Cancer (2014)