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  1. Article

    Open Access

    TRAF6 promotes spinal microglial M1 polarization to aggravate neuropathic pain by activating the c-JUN/NF-kB signaling pathway

    The neuropathic pain with complex networks of neuroinflammatory activation severely limits clinical therapeutic research. TNF receptor-associated factor 6 (TRAF6) is associated with multiple inflammatory disea...

    Yu Zhao, Tiegang Li, Lichun Zhang, Jun Yang, Feng Zhao in Cell Biology and Toxicology (2024)

  2. Article

    Open Access

    Safety of embryo cryopreservation: insights from mid-term placental transcriptional changes

    In recent years, with benefits from the continuous improvement of clinical technology and the advantage of fertility preservation, the application of embryo cryopreservation has been growing rapidly worldwide....

    Qin-Yu Luo, Si-Wei Zhang, Hai-Yan Wu, Jia-Ying Mo in Reproductive Biology and Endocrinology (2024)

  3. Article

    Open Access

    Associations between the choroid plexus and tau in Alzheimer’s disease using an active learning segmentation pipeline

    The cerebrospinal fluid (CSF), primarily generated by the choroid plexus (ChP), is the major carrier of the glymphatic system. The alternations of CSF production and the ChP can be associated with the Alzheime...

    Jiaxin Li, Yueqin Hu, Yunzhi Xu, Xue Feng, Craig H. Meyer in Fluids and Barriers of the CNS (2024)

  4. Article

    Open Access

    Hybrid teaching after COVID-19: advantages, challenges and optimization strategies

    In the post-pandemic era of higher education, hybrid teaching has emerged as a prevalent approach and is anticipated to persist as a defining trend in the future teaching reforms worldwide. However, despite it...

    **aoran Wang, Jiangheng Liu, Shuwei Jia, Chunmei Hou in BMC Medical Education (2024)

  5. Article

    Open Access

    Temporal relationship between hepatic steatosis and fasting blood glucose elevation: a longitudinal analysis from China and UK

    The link between nonalcoholic fatty liver disease and type 2 diabetes has not been fully established. We investigated the temporal relationship between nonalcoholic fatty liver disease (NAFLD) and type 2 diabe...

    Yujie Liu, **an Liang, Yifan Hu, Ning Zhang, **ngren Zhu, Yuemei Feng in BMC Public Health (2024)

  6. Article

    Open Access

    The impact of Paclitaxel-based hyperthermic intraperitoneal chemotherapy in advanced high-grade serous ovarian cancer patients - interim analysis of safety and immediate efficacy of a randomized control trial (C-HOC trial)

    This study evaluates the potential superiority of combining paclitaxel-based hyperthermic intraperitoneal chemotherapy (HIPEC) with sequential intravenous neoadjuvant chemotherapy over intravenous neoadjuvant ...

    Qun Wang, Hua Liu, Yuhong Shen, Lifei Shen, Jian Li in Journal of Ovarian Research (2024)

  7. Article

    Open Access

    Unveiling the translational dynamics of lychee (Litchi chinesis Sonn.) in response to cold stress

    Cold stress poses a significant threat to the quality and productivity of lychee (Litchi chinensis Sonn.). While previous research has extensively explored the genomic and transcriptomic responses to cold stress ...

    Mingming Chen, Shuangfeng Dai, Daming Chen, Haomin Chen, Naijie Feng in BMC Genomics (2024)

  8. Article

    Open Access

    Hierarchical adaptive evolution framework for privacy-preserving data publishing

    The growing need for data publication and the escalating concerns regarding data privacy have led to a surge in interest in Privacy-Preserving Data Publishing (PPDP) across research, industry, and government s...

    Mingshan You, Yong-Feng Ge, Kate Wang, Hua Wang, **li Cao in World Wide Web (2024)

  9. Article

    Open Access

    Deep metagenomic sequencing unveils novel SAR202 lineages and their vertical adaptation in the ocean

    SAR202 bacteria in the Chloroflexota phylum are abundant and widely distributed in the ocean. Their genome coding capacities indicate their potential roles in degrading complex and recalcitrant organic compoun...

    Changfei He, Daniel Fucich, Ana Sosa, Hualong Wang, **jun Kan in Communications Biology (2024)

  10. Article

    Open Access

    Development and internal validation of a model for predicting cefoperazone/sulbactam-associated coagulation disorders in Chinese inpatients

    The use of cefoperazone/sulbactam (CPZ/SAM) could commonly cause vitamin K-dependent coagulation disorders and even hemorrhage sometimes. However, there is a lack of prediction tools estimating the risk for th...

    An Fu, Feng Ge, Yanwei Wang, Haili Guo, Man Zhu, Shu Li in BMC Pharmacology and Toxicology (2024)

  11. Article

    Open Access

    eHSP90α in front-line therapy in EGFR exon 19 deletion and 21 Leu858Arg mutations in advanced lung adenocarcinoma

    Extracellular heat shock protein 90 AA1(eHSP90α) is intricately linked to tumor progression and prognosis. This study aimed to investigate the difference in the value of eHSP90α in post-treatment response asse...

    Yingzhen Bian, Haizhou Liu, **glei Huang, Zhaorong Feng, Yanyan Lin in BMC Cancer (2024)

  12. Article

    Open Access

    The type III effector NopL interacts with GmREM1a and GmNFR5 to promote symbiosis in soybean

    The establishment of symbiotic interactions between leguminous plants and rhizobia requires complex cellular programming activated by Rhizobium Nod factors (NFs) as well as type III effector (T3E)-mediated sym...

    Chao Ma, **hui Wang, Yongkang Gao, Xulun Dong, Haojie Feng in Nature Communications (2024)

  13. Article

    Open Access

    Correction: Apatinib combined with temozolomide in diffuse midline glioma: a novel and effective therapy

    Yu-An Li, Chuan Zhao, **g-**g Ge, Cheng Li, Feng-Jun Xue, Shao-Pei Qi in BMC Cancer (2024)

  14. Article

    Open Access

    Erratum to: Oil-soluble polymer brushes-functionalized nanoMOFs for highly efficient friction and wear reduction

    Jianxi Liu, Yong Qian, Dongsheng Li, Wei Wu, Mengchen Zhang, Jie Yan, Bin Li in Friction (2024)

  15. Article

    Open Access

    Construction and validation of a nomogram for blood transfusion after open reduction and internal fixation (ORIF) of proximal humeral fractures in the elderly: a cross-sectional study

    Few studies have focused on the risk factors leading to postoperative blood transfusion after open reduction and internal fixation (ORIF) of proximal humeral fractures (PHFs) in the elderly. Therefore, we desi...

    Lu-ying Chen, Ji-qi Wang, You-ming Zhao, Yong-zeng Feng in BMC Musculoskeletal Disorders (2024)

  16. Article

    Open Access

    Author Correction: Divergent landscapes of A-to-I editing in postmortem and living human brain

    Miguel Rodriguez de los Santos, Brian H. Kopell in Nature Communications (2024)

  17. Article

    Open Access

    Associations between 25 hydroxyvitamin D concentration and spontaneous abortion

    Spontaneous abortion is a common complication of pregnancy that can lead to adverse physical and psychological outcomes for women. Vitamin D is reported to be associated with reproductive functions, whereas it...

    Hong** Zhang, **ngru Ding, **anqing Hu, Yi-**n Cai, Haiying Chen in BMC Public Health (2024)

  18. Article

    Open Access

    Evaluation of the FPMC respiratory panel for detection of respiratory tract pathogens in nasopharyngeal swab and sputum specimens

    The performance of the new Respiratory Pathogen panel (fluorescent probe melting curve, FPMC) for the qualitative detection of 12 organisms (chlamydia pneumoniae, mycoplasma pneumoniae, adenovirus, influenza A...

    Li Xue, Jianhong Zhu, Ke Lei, Zeshi Liu, Yiwei Tang, Bo Zhong, Ning Gao in Virology Journal (2024)

  19. Article

    Open Access

    Immunohistochemistry staining of Eag1 and p16/Ki-67 can help improve the management of patients with cervical intraepithelial Neoplasia after cold knife conversion

    Immunohistochemistry (IHC) is widely used in the management of patients with cervical intraepithelial neoplasia (CIN) but still has many limitations in clinical practice. We analyzed the correlation of new bio...

    Shikang Qiu, Qiannan Wang, Huihui Jiang, Limin Feng in Diagnostic Pathology (2024)

  20. Article

    Open Access

    Biomechanical evaluation of different medial column fixation patterns for valgus pilon fractures

    The purpose of this study was to perform a biomechanical analysis to compare different medial column fixation patterns for valgus pilon fractures in a case-based model.

    Bing-Hao Wang, Bin-Bin Zhang, Zi-Ling Gong, Jiong Mei in BMC Musculoskeletal Disorders (2024)

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